Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
O60674 Janus kinase 2 Kinase 644 0.385 0.885 0.65 0.300 None 0.979 516 12 2005 2020
Entrez Id: 4352
Gene Symbol: MPL
MPL
P40238 MPL proto-oncogene, thrombopoietin receptor Receptor 222 0.510 0.692 4.1E-09 0.500 None 0.979 95 5 1995 2020
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11
Q06124 protein tyrosine phosphatase non-receptor type 11 702 0.385 0.923 1.00 0.100 None 0.909 11 3 2005 2018
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.030 None 1.000 3 2 2012 2016
Entrez Id: 54790
Gene Symbol: TET2
TET2
Q6N021 tet methylcytosine dioxygenase 2 362 0.458 0.808 4.3E-54 0.100 None 0.958 24 1 2009 2019
Entrez Id: 3815
Gene Symbol: KIT
KIT
P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 715 0.366 0.808 0.98 0.480 None 1.000 10 1 1994 2015
Entrez Id: 9021
Gene Symbol: SOCS3
SOCS3
O14543 suppressor of cytokine signaling 3 Enzyme modulator 375 0.434 0.808 0.75 0.080 None 1.000 8 1 2008 2019
Entrez Id: 3418
Gene Symbol: IDH2
IDH2
P48735 isocitrate dehydrogenase (NADP(+)) 2 380 0.434 0.808 0.88 0.070 None 1.000 7 1 2010 2019
Entrez Id: 1441
Gene Symbol: CSF3R
CSF3R
Q99062 colony stimulating factor 3 receptor Signaling 120 0.550 0.692 1.5E-10 0.060 None 1.000 6 1 2009 2020
Entrez Id: 7015
Gene Symbol: TERT
TERT
O14746 telomerase reverse transcriptase Enzyme 703 0.374 0.846 0.99 0.050 None 1.000 5 1 2014 2018
Entrez Id: 3718
Gene Symbol: JAK3
JAK3
P52333 Janus kinase 3 Kinase 194 0.505 0.731 5.9E-06 0.400 None 1.000 4 1 2010 2014
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
P01111 NRAS proto-oncogene, GTPase Enzyme modulator 611 0.390 0.808 0.49 0.020 None 1.000 2 1 1992 2009
Entrez Id: 7037
Gene Symbol: TFRC
TFRC
P02786 transferrin receptor Enzyme 359 0.437 0.885 7.0E-05 0.020 None 1.000 2 1 2009 2010
Entrez Id: 2122
Gene Symbol: MECOM
MECOM
Q03112 MDS1 and EVI1 complex locus 191 0.513 0.731 1.00 0.020 None 1.000 2 1 1997 2018
Entrez Id: 27352
Gene Symbol: SGSM3
SGSM3
Q96HU1 small G protein signaling modulator 3 Enzyme 259 0.469 0.808 3.4E-15 0.010 None 1.000 1 1 2019 2019
Entrez Id: 19
Gene Symbol: ABCA1
ABCA1
O95477 ATP binding cassette subfamily A member 1 Transporter 291 0.467 0.846 1.5E-13 0.010 None 1.000 1 1 2012 2012
Entrez Id: 10767
Gene Symbol: HBS1L
HBS1L
Q9Y450 HBS1 like translational GTPase Enzyme 49 0.705 0.462 1.9E-07 0.010 None 1.000 1 1 2018 2018
Entrez Id: 3077
Gene Symbol: HFE
HFE
Q30201 homeostatic iron regulator 415 0.436 0.846 2.6E-08 0.010 None 1.000 1 1 2009 2009
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
O00206 toll like receptor 4 1174 0.321 0.962 4.6E-09 0.010 None 1.000 1 1 2018 2018
Entrez Id: 7490
Gene Symbol: WT1
WT1
P19544 WT1 transcription factor Nucleic acid binding 446 0.422 0.808 1.00 0.010 None 1.000 1 1 2015 2015
Entrez Id: 25
Gene Symbol: ABL1
ABL1
P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 395 0.432 0.923 1.00 0.100 None 0.975 159 0 1993 2020
Entrez Id: 811
Gene Symbol: CALR
CALR
P27797 calreticulin Calcium-binding protein 487 0.413 0.923 0.89 0.100 None 0.980 102 0 2014 2020
Entrez Id: 613
Gene Symbol: BCR
BCR
P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 392 0.431 0.885 0.99 0.100 None 0.942 69 0 1992 2019
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
P11362 fibroblast growth factor receptor 1 Kinase 816 0.362 0.885 1.00 0.100 None 1.000 34 0 1998 2018
Entrez Id: 6646
Gene Symbol: SOAT1
SOAT1
P35610 sterol O-acyltransferase 1 Enzyme 389 0.424 0.846 7.4E-10 0.100 None 1.000 33 0 2006 2020