Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2878
Gene Symbol: GPX3
GPX3
P22352 glutathione peroxidase 3 Enzyme 156 0.522 0.769 5.1E-02 0.010 None 1.000 1 4 2009 2009
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.090 None 1.000 9 3 1995 2018
Entrez Id: 7515
Gene Symbol: XRCC1
XRCC1
P18887 X-ray repair cross complementing 1 410 0.421 0.923 6.3E-09 0.080 None 0.750 8 3 2009 2016
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
P01111 NRAS proto-oncogene, GTPase Enzyme modulator 611 0.390 0.808 0.49 0.030 None 1.000 3 3 2014 2018
Entrez Id: 472
Gene Symbol: ATM
ATM
Q13315 ATM serine/threonine kinase Kinase 684 0.374 0.885 5.6E-47 0.030 None 0.667 3 3 2012 2015
Entrez Id: 1591
Gene Symbol: CYP24A1
CYP24A1
Q07973 cytochrome P450 family 24 subfamily A member 1 Enzyme 171 0.518 0.692 3.2E-23 0.020 None 1.000 2 3 2012 2012
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.100 None 1.000 20 2 2008 2019
Entrez Id: 5979
Gene Symbol: RET
RET
P07949 ret proto-oncogene Kinase 607 0.392 0.885 1.00 0.100 None 0.846 13 2 2003 2018
Entrez Id: 2304
Gene Symbol: FOXE1
FOXE1
O00358 forkhead box E1 Transcription factor 102 0.573 0.731 0.79 0.100 None 1.000 10 2 2013 2018
Entrez Id: 7173
Gene Symbol: TPO
TPO
P07202 thyroid peroxidase Enzyme 306 0.455 0.846 1.8E-21 0.050 None 1.000 5 2 1995 2013
Entrez Id: 729582
Gene Symbol: DIRC3
DIRC3
disrupted in renal carcinoma 3 16 0.780 0.308 3.4E-07 0.130 None 1.000 3 2 2013 2017
Entrez Id: 1594
Gene Symbol: CYP27B1
CYP27B1
O15528 cytochrome P450 family 27 subfamily B member 1 Enzyme 229 0.502 0.769 1.9E-07 0.020 None 1.000 2 2 2012 2012
Entrez Id: 3084
Gene Symbol: NRG1
NRG1
Q02297 neuregulin 1 Signaling 304 0.464 0.885 1.00 0.110 None 1.000 2 2 2013 2017
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.020 None 1.000 2 2 1996 2013
Entrez Id: 120227
Gene Symbol: CYP2R1
CYP2R1
Q6VVX0 cytochrome P450 family 2 subfamily R member 1 139 0.563 0.731 3.8E-10 0.010 None 1.000 1 2 2012 2012
Entrez Id: 2309
Gene Symbol: FOXO3
FOXO3
O43524 forkhead box O3 381 0.431 0.808 0.99 0.010 None 1.000 1 2 2018 2018
Entrez Id: 6392
Gene Symbol: SDHD
SDHD
O14521 succinate dehydrogenase complex subunit D Transporter 348 0.472 0.885 0.34 0.010 None 1.000 1 2 2017 2017
Entrez Id: 7253
Gene Symbol: TSHR
TSHR
P16473 thyroid stimulating hormone receptor G-protein coupled receptor 250 0.486 0.808 3.0E-15 0.100 None 0.944 18 1 1992 2018
Entrez Id: 7517
Gene Symbol: XRCC3
XRCC3
O43542 X-ray repair cross complementing 3 184 0.505 0.769 1.9E-10 0.050 None 1.000 5 1 2005 2016
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1119 0.319 0.885 1.00 0.030 None 1.000 3 1 2008 2019
Entrez Id: 7516
Gene Symbol: XRCC2
XRCC2
O43543 X-ray repair cross complementing 2 187 0.512 0.731 4.0E-07 0.030 None 1.000 3 1 2011 2014
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1083 0.322 0.885 1.00 0.030 None 1.000 3 1 2008 2019
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.020 None 1.000 2 1 2011 2012
Entrez Id: 3486
Gene Symbol: IGFBP3
IGFBP3
P17936 insulin like growth factor binding protein 3 Enzyme modulator 350 0.439 0.808 0.91 0.020 None 0.500 2 1 2012 2014
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
metastasis associated lung adenocarcinoma transcript 1 336 0.435 0.846 0.010 None 1.000 1 1 2020 2020