Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 183
Gene Symbol: AGT
AGT
P01019 angiotensinogen Enzyme modulator 765 0.367 0.923 5.0E-08 0.100 None 1.000 33 0 2009 2020
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.300 None 1.000 23 0 2002 2020
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
P17931 galectin 3 Signaling 557 0.392 0.846 2.3E-05 0.100 None 1.000 16 0 2015 2020
Entrez Id: 1490
Gene Symbol: CCN2
CCN2
P29279 cellular communication network factor 2 Signaling 518 0.399 0.846 5.0E-04 0.090 None 1.000 9 0 2009 2019
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.270 None 1.000 8 0 2005 2019
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
P84022 SMAD family member 3 Transcription factor 470 0.415 0.923 0.80 0.070 None 1.000 7 0 2014 2019
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
microRNA 21 726 0.363 0.846 0.070 None 1.000 7 0 2015 2018
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
P05121 serpin family E member 1 Enzyme modulator 770 0.359 0.885 4.4E-02 0.240 None 1.000 6 0 2002 2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1193 0.320 0.923 1.00 0.060 None 1.000 6 0 2017 2019
Entrez Id: 6761
Gene Symbol: ST2
ST2
suppression of tumorigenicity 2 96 0.576 0.692 0.060 None 1.000 6 0 2018 2020
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme Enzyme 1082 0.328 0.923 1.0E-37 0.050 None 1.000 5 0 2013 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.050 None 1.000 5 0 2009 2019
Entrez Id: 60
Gene Symbol: ACTB
ACTB
P60709 actin beta Cellular structure 1110 0.325 0.923 0.99 0.050 None 1.000 5 0 2010 2019
Entrez Id: 4087
Gene Symbol: SMAD2
SMAD2
Q15796 SMAD family member 2 Transcription factor 289 0.456 0.808 1.00 0.050 None 1.000 5 0 2006 2020
Entrez Id: 5972
Gene Symbol: REN
REN
P00797 renin Enzyme 721 0.370 0.923 2.4E-07 0.040 None 0.750 4 0 2004 2018
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
P08253 matrix metallopeptidase 2 Enzyme 1021 0.333 0.923 0.84 0.040 None 1.000 4 0 2018 2019
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3
Q96P20 NLR family pyrin domain containing 3 805 0.361 0.962 8.1E-04 0.040 None 1.000 4 0 2018 2019
Entrez Id: 2335
Gene Symbol: FN1
FN1
P02751 fibronectin 1 Signaling 724 0.365 0.962 1.4E-03 0.230 None 1.000 4 0 2013 2020
Entrez Id: 8074
Gene Symbol: FGF23
FGF23
Q9GZV9 fibroblast growth factor 23 Signaling 305 0.460 0.731 3.1E-02 0.040 None 1.000 4 0 2016 2019
Entrez Id: 285
Gene Symbol: ANGPT2
ANGPT2
O15123 angiopoietin 2 Signaling 457 0.410 0.846 0.83 0.040 None 1.000 4 0 2013 2020
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
P05305 endothelin 1 Signaling 679 0.380 0.846 0.46 0.230 None 1.000 4 0 2001 2017
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.040 None 1.000 4 0 2016 2019
Entrez Id: 738
Gene Symbol: VPS51
VPS51
Q9UID3 VPS51 subunit of GARP complex 292 0.452 0.846 1.1E-08 0.040 None 1.000 4 0 2013 2020
Entrez Id: 54822
Gene Symbol: TRPM7
TRPM7
Q96QT4 transient receptor potential cation channel subfamily M member 7 Ion channel 151 0.531 0.731 5.2E-16 0.040 None 1.000 4 0 2017 2020
Entrez Id: 177
Gene Symbol: AGER
AGER
Q15109 advanced glycosylation end-product specific receptor Receptor 450 0.420 0.885 6.4E-16 0.210 None 1.000 3 0 2011 2016