Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
P08183 ATP binding cassette subfamily B member 1 Transporter 933 0.344 0.885 1.3E-05 0.010 None 1.000 1 0 1996 1996
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.080 None 1.000 8 0 1994 2017
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
Q13485 SMAD family member 4 Transcription factor 575 0.401 0.808 1.00 0.030 None 1.000 3 0 2014 2018
Entrez Id: 8626
Gene Symbol: TP63
TP63
Q9H3D4 tumor protein p63 Transcription factor 816 0.362 0.769 1.00 0.030 None 1.000 3 0 2002 2016
Entrez Id: 2078
Gene Symbol: ERG
ERG
P11308 ETS transcription factor ERG Transcription factor 298 0.453 0.808 0.96 0.020 None 1.000 2 0 2009 2017
Entrez Id: 4609
Gene Symbol: MYC
MYC
P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 821 0.344 0.923 1.00 0.020 None 1.000 2 0 2001 2018
Entrez Id: 1045
Gene Symbol: CDX2
CDX2
Q99626 caudal type homeobox 2 Transcription factor 278 0.458 0.769 0.53 0.010 None 1.000 1 0 2005 2005
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 1044 0.327 0.923 0.98 0.010 None 1.000 1 0 2015 2015
Entrez Id: 3175
Gene Symbol: ONECUT1
ONECUT1
Q9UBC0 one cut homeobox 1 Transcription factor 36 0.686 0.346 0.52 0.010 None < 0.001 1 0 2014 2014
Entrez Id: 3663
Gene Symbol: IRF5
IRF5
Q13568 interferon regulatory factor 5 Transcription factor 226 0.489 0.731 9.0E-03 0.010 None 1.000 1 0 2011 2011
Entrez Id: 6304
Gene Symbol: SATB1
SATB1
Q01826 SATB homeobox 1 Transcription factor 147 0.525 0.769 0.99 0.010 None 1.000 1 0 2013 2013
Entrez Id: 7088
Gene Symbol: TLE1
TLE1
Q04724 TLE family member 1, transcriptional corepressor Transcription factor 106 0.560 0.654 1.00 0.010 None 1.000 1 0 2017 2017
Entrez Id: 7767
Gene Symbol: ZNF224
ZNF224
Q9NZL3 zinc finger protein 224 Transcription factor 23 0.711 0.385 3.1E-03 0.010 None 1.000 1 0 2016 2016
Entrez Id: 864
Gene Symbol: RUNX3
RUNX3
Q13761 RUNX family transcription factor 3 Transcription factor 281 0.459 0.731 0.84 0.010 None 1.000 1 0 2012 2012
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.040 None 1.000 4 0 1995 2000
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
P01135 transforming growth factor alpha Signaling 376 0.432 0.885 0.72 0.020 None 1.000 2 0 1999 2018
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
P10145 C-X-C motif chemokine ligand 8 Signaling 1254 0.310 0.962 2.7E-04 0.010 None 1.000 1 0 2017 2017
Entrez Id: 4838
Gene Symbol: NODAL
NODAL
Q96S42 nodal growth differentiation factor Signaling 89 0.588 0.731 0.97 0.010 None 1.000 1 0 2019 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.010 None 1.000 1 0 1995 1995
Entrez Id: 3547
Gene Symbol: IGSF1
IGSF1
Q8N6C5 immunoglobulin superfamily member 1 Receptor 66 0.608 0.500 1.00 0.010 None 1.000 1 0 2013 2013
Entrez Id: 3159
Gene Symbol: HMGA1
HMGA1
P17096 high mobility group AT-hook 1 Nucleic acid binding 206 0.494 0.769 0.83 0.020 None 1.000 2 0 2015 2016
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
P51587 BRCA2 DNA repair associated Nucleic acid binding 656 0.379 0.846 2.4E-25 0.020 None 1.000 2 0 2008 2018
Entrez Id: 1869
Gene Symbol: E2F1
E2F1
Q01094 E2F transcription factor 1 Nucleic acid binding 324 0.441 0.846 0.99 0.010 None 1.000 1 0 2008 2008
Entrez Id: 27250
Gene Symbol: PDCD4
PDCD4
Q53EL6 programmed cell death 4 Nucleic acid binding 198 0.494 0.769 3.4E-07 0.010 None 1.000 1 0 2007 2007
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
P52701 mutS homolog 6 Nucleic acid binding 296 0.462 0.731 3.7E-05 0.010 None 1.000 1 0 2003 2003