Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
P08183 ATP binding cassette subfamily B member 1 Transporter 933 0.344 0.885 1.3E-05 0.010 None 1.000 1 0 1990 1990
Entrez Id: 3952
Gene Symbol: LEP
LEP
P41159 leptin 931 0.349 0.846 0.46 0.020 None 1.000 2 0 2001 2018
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.300 None 1.000 2 0 2011 2017
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
P10451 secreted phosphoprotein 1 824 0.353 0.885 2.1E-06 0.300 None 1.000 1 0 2006 2006
Entrez Id: 4609
Gene Symbol: MYC
MYC
P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 821 0.344 0.923 1.00 0.010 None 1.000 1 0 2015 2015
Entrez Id: 836
Gene Symbol: CASP3
CASP3
P42574 caspase 3 Enzyme 819 0.351 0.923 0.10 0.010 None 1.000 1 0 2015 2015
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10
H3 histone pseudogene 10 769 0.350 0.846 0.010 None 1.000 1 0 2004 2004
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
O60603 toll like receptor 2 749 0.361 0.923 1.0E-06 0.010 None 1.000 1 0 2019 2019
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
P38398 BRCA1 DNA repair associated Enzyme 747 0.367 0.923 9.2E-29 0.010 None 1.000 1 0 2019 2019
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
microRNA 21 726 0.363 0.846 0.010 None 1.000 1 0 2009 2009
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1
P09429 high mobility group box 1 Nucleic acid binding 724 0.368 0.923 0.82 0.010 None 1.000 1 0 2019 2019
Entrez Id: 7015
Gene Symbol: TERT
TERT
O14746 telomerase reverse transcriptase Enzyme 703 0.374 0.846 0.99 0.010 None 1.000 1 0 2017 2017
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
P01112 HRas proto-oncogene, GTPase Enzyme modulator 698 0.378 0.885 8.0E-02 0.310 None 1.000 2 0 1988 2017
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
P46531 notch receptor 1 693 0.369 0.885 1.00 0.010 None 1.000 1 0 2011 2011
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
Q96EB6 sirtuin 1 Epigenetic regulator 675 0.378 0.885 8.7E-02 0.300 None 1.000 1 0 2012 2012
Entrez Id: 3105
Gene Symbol: HLA-A
HLA-A
P04439 major histocompatibility complex, class I, A 672 0.370 0.846 1.3E-03 0.010 None 1.000 1 0 1994 1994
Entrez Id: 3082
Gene Symbol: HGF
HGF
P14210 hepatocyte growth factor Enzyme 671 0.374 0.885 1.00 0.010 None 1.000 1 0 2005 2005
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
P04179 superoxide dismutase 2 Enzyme 668 0.379 0.923 0.15 0.300 None 1.000 1 0 2011 2011
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
P09211 glutathione S-transferase pi 1 610 0.383 0.923 1.4E-02 0.010 None 1.000 1 0 2019 2019
Entrez Id: 3481
Gene Symbol: IGF2
IGF2
P01344 insulin like growth factor 2 604 0.390 0.885 4.4E-02 0.020 None 1.000 2 0 1991 1993
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1
Q13635 patched 1 604 0.398 0.885 1.00 0.300 None 1.000 1 0 1998 1998
Entrez Id: 6285
Gene Symbol: S100B
S100B
P04271 S100 calcium binding protein B Calcium-binding protein 599 0.383 0.923 4.4E-02 0.300 None 1.000 1 0 2017 2017
Entrez Id: 5340
Gene Symbol: PLG
PLG
P00747 plasminogen Enzyme 586 0.389 0.923 1.0E-02 0.010 None 1.000 1 0 2011 2011
Entrez Id: 5111
Gene Symbol: PCNA
PCNA
P12004 proliferating cell nuclear antigen Nucleic acid binding 581 0.382 0.846 0.98 0.300 None 1.000 1 0 2011 2011
Entrez Id: 1351
Gene Symbol: COX8A
COX8A
P10176 cytochrome c oxidase subunit 8A Enzyme 526 0.400 0.846 0.12 0.010 None 1.000 1 0 2019 2019