Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.010 None 1.000 1 0 2015 2015
Entrez Id: 4609
Gene Symbol: MYC
MYC
P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 821 0.344 0.923 1.00 0.010 None 1.000 1 0 2015 2015
Entrez Id: 836
Gene Symbol: CASP3
CASP3
P42574 caspase 3 Enzyme 819 0.351 0.923 0.10 0.010 None 1.000 1 0 2015 2015
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.310 None 0.500 2 0 2011 2016
Entrez Id: 1559
Gene Symbol: CYP2C9
CYP2C9
P11712 cytochrome P450 family 2 subfamily C member 9 201 0.506 0.885 1.3E-10 0.310 None 1.000 2 0 2006 2016
Entrez Id: 2735
Gene Symbol: GLI1
GLI1
P08151 GLI family zinc finger 1 369 0.431 0.846 7.7E-14 0.010 None 1.000 1 0 2016 2016
Entrez Id: 1557
Gene Symbol: CYP2C19
CYP2C19
P33261 cytochrome P450 family 2 subfamily C member 19 274 0.467 0.846 6.5E-20 0.010 None 1.000 1 0 2016 2016
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.330 None 1.000 5 0 2004 2017
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.030 None 1.000 3 0 2004 2017
Entrez Id: 1019
Gene Symbol: CDK4
CDK4
P11802 cyclin dependent kinase 4 Kinase 433 0.412 0.808 6.3E-02 0.310 None 1.000 2 0 2011 2017
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
P01112 HRas proto-oncogene, GTPase Enzyme modulator 698 0.378 0.885 8.0E-02 0.310 None 1.000 2 0 1988 2017
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.300 None 1.000 2 0 2011 2017
Entrez Id: 2152
Gene Symbol: F3
F3
P13726 coagulation factor III, tissue factor Receptor 456 0.415 0.846 1.9E-02 0.020 None 1.000 2 0 2017 2017
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
P37173 transforming growth factor beta receptor 2 Kinase 502 0.413 0.846 0.13 0.300 None 1.000 1 0 2017 2017
Entrez Id: 8826
Gene Symbol: IQGAP1
IQGAP1
P46940 IQ motif containing GTPase activating protein 1 Enzyme modulator 109 0.560 0.692 1.00 0.300 None 1.000 1 0 2017 2017
Entrez Id: 634
Gene Symbol: CEACAM1
CEACAM1
P13688 CEA cell adhesion molecule 1 167 0.525 0.731 7.9E-04 0.010 None 1.000 1 0 2017 2017
Entrez Id: 7015
Gene Symbol: TERT
TERT
O14746 telomerase reverse transcriptase Enzyme 703 0.374 0.846 0.99 0.010 None 1.000 1 0 2017 2017
Entrez Id: 6657
Gene Symbol: SOX2
SOX2
P48431 SRY-box transcription factor 2 Transcription factor 503 0.405 0.808 0.71 0.300 None 1.000 1 0 2017 2017
Entrez Id: 6285
Gene Symbol: S100B
S100B
P04271 S100 calcium binding protein B Calcium-binding protein 599 0.383 0.923 4.4E-02 0.300 None 1.000 1 0 2017 2017
Entrez Id: 7035
Gene Symbol: TFPI
TFPI
P10646 tissue factor pathway inhibitor Enzyme modulator 230 0.486 0.808 0.25 0.010 None 1.000 1 0 2017 2017
Entrez Id: 406903
Gene Symbol: MIR10B
MIR10B
microRNA 10b 167 0.509 0.808 0.010 None 1.000 1 0 2017 2017
Entrez Id: 10419
Gene Symbol: PRMT5
PRMT5
O14744 protein arginine methyltransferase 5 Epigenetic regulator 131 0.539 0.769 1.00 0.010 None 1.000 1 0 2017 2017
Entrez Id: 406953
Gene Symbol: MIR18A
MIR18A
microRNA 18a 154 0.520 0.846 0.010 None 1.000 1 0 2017 2017
Entrez Id: 10788
Gene Symbol: IQGAP2
IQGAP2
Q13576 IQ motif containing GTPase activating protein 2 Enzyme modulator 46 0.674 0.269 8.5E-27 0.300 None 1.000 1 0 2017 2017
Entrez Id: 23510
Gene Symbol: KCTD2
KCTD2
Q14681 potassium channel tetramerization domain containing 2 4 0.931 0.115 0.20 0.010 None 1.000 1 0 2017 2017