Source: CURATED ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		P35222 catenin beta 1 130 0.303 0.885 1.00 0.320 None 1.000 1 0 2014 2017
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 182 0.305 0.923 0.26 0.350 None 1.000 1 0 2009 2019
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11 		Q06124 protein tyrosine phosphatase non-receptor type 11 51 0.385 0.923 1.00 0.300 None 1.000 1 0 2017 2017
Entrez Id: 4297
Gene Symbol: KMT2A
KMT2A 		Q03164 lysine methyltransferase 2A 46 0.410 0.885 1.00 0.300 None 1.000 1 0 2017 2017
Entrez Id: 4204
Gene Symbol: MECP2
MECP2 		P51608 methyl-CpG binding protein 2 Epigenetic regulator 90 0.414 0.846 0.89 0.400 None 0.993 2 0 2000 2020
Entrez Id: 29072
Gene Symbol: SETD2
SETD2 		Q9BYW2 SET domain containing 2, histone lysine methyltransferase Epigenetic regulator 28 0.424 0.846 1.00 0.300 None 1.000 1 0 2017 2017
Entrez Id: 27086
Gene Symbol: FOXP1
FOXP1 		Q9H334 forkhead box P1 18 0.460 0.808 1.00 0.350 None 1.000 1 0 2015 2017
Entrez Id: 6925
Gene Symbol: TCF4
TCF4 		P15884 transcription factor 4 Transcription factor 47 0.464 0.846 1.00 0.350 None 1.000 1 0 2011 2019
Entrez Id: 6323
Gene Symbol: SCN1A
SCN1A 		P35498 sodium voltage-gated channel alpha subunit 1 Ion channel 42 0.477 0.808 1.00 0.330 None 1.000 1 0 2016 2019
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2 		Q9NQB0 transcription factor 7 like 2 29 0.485 0.846 1.00 0.310 None 0.500 1 0 2015 2017
Entrez Id: 5079
Gene Symbol: PAX5
PAX5 		Q02548 paired box 5 8 0.487 0.654 1.00 0.300 None 1.000 1 0 2017 2017
Entrez Id: 6616
Gene Symbol: SNAP25
SNAP25 		P60880 synaptosome associated protein 25 Transporter 36 0.489 0.808 0.99 0.300 None 1.000 1 0 2018 2018
Entrez Id: 5058
Gene Symbol: PAK1
PAK1 		Q13153 p21 (RAC1) activated kinase 1 Kinase 16 0.494 0.808 1.3E-03 0.300 moderate 1.000 1 0 2018 2018
Entrez Id: 57492
Gene Symbol: ARID1B
ARID1B 		Q8NFD5 AT-rich interaction domain 1B 15 0.503 0.846 1.00 0.320 None 0.750 2 0 2012 2019
Entrez Id: 26040
Gene Symbol: SETBP1
SETBP1 		Q9Y6X0 SET binding protein 1 30 0.503 0.808 1.00 0.300 None 1.000 1 0 2017 2017
Entrez Id: 8243
Gene Symbol: SMC1A
SMC1A 		Q14683 structural maintenance of chromosomes 1A 18 0.509 0.808 1.00 0.300 None 1.000 1 0 2018 2018
Entrez Id: 2904
Gene Symbol: GRIN2B
GRIN2B 		Q13224 glutamate ionotropic receptor NMDA type subunit 2B Ion channel 28 0.510 0.692 1.00 0.340 None 1.000 2 0 2012 2018
Entrez Id: 6334
Gene Symbol: SCN8A
SCN8A 		Q9UQD0 sodium voltage-gated channel alpha subunit 8 Ion channel 60 0.510 0.731 1.00 0.330 None 1.000 1 0 2015 2018
Entrez Id: 8493
Gene Symbol: PPM1D
PPM1D 		O15297 protein phosphatase, Mg2+/Mn2+ dependent 1D Enzyme 16 0.513 0.808 2.2E-11 0.310 None 1.000 1 0 2017 2017
Entrez Id: 4208
Gene Symbol: MEF2C
MEF2C 		Q06413 myocyte enhancer factor 2C Transcription factor 23 0.517 0.769 1.7E-02 0.340 None 1.000 1 0 2013 2018
Entrez Id: 6326
Gene Symbol: SCN2A
SCN2A 		Q99250 sodium voltage-gated channel alpha subunit 2 Ion channel 20 0.518 0.731 1.00 0.360 None 1.000 2 0 2017 2019
Entrez Id: 2290
Gene Symbol: FOXG1
FOXG1 		P55316 forkhead box G1 45 0.522 0.692 0.94 0.350 None 1.000 1 0 2014 2019
Entrez Id: 6792
Gene Symbol: CDKL5
CDKL5 		O76039 cyclin dependent kinase like 5 Kinase 40 0.522 0.692 1.00 0.400 None 0.962 1 0 2004 2020
Entrez Id: 2775
Gene Symbol: GNAO1
GNAO1 		P09471 G protein subunit alpha o1 Enzyme modulator 17 0.523 0.808 0.99 0.310 None 1.000 1 0 2016 2018
Entrez Id: 6812
Gene Symbol: STXBP1
STXBP1 		P61764 syntaxin binding protein 1 Transporter 20 0.532 0.692 1.00 0.370 None 1.000 2 0 2016 2019