Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		P40692 mutL homolog 1 Nucleic acid binding 526 0.399 0.808 3.4E-05 0.100 None 0.941 17 1 1996 2019
Entrez Id: 6392
Gene Symbol: SDHD
SDHD 		O14521 succinate dehydrogenase complex subunit D Transporter 348 0.472 0.885 0.34 0.100 None 0.941 17 1 2000 2019
Entrez Id: 5071
Gene Symbol: PRKN
PRKN 		O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 409 0.431 0.846 6.9E-07 0.100 None 0.938 16 2 2002 2018
Entrez Id: 659
Gene Symbol: BMPR2
BMPR2 		Q13873 bone morphogenetic protein receptor type 2 Kinase 146 0.538 0.654 1.00 0.100 None 1.000 16 0 2002 2014
Entrez Id: 324
Gene Symbol: APC
APC 		P25054 APC regulator of WNT signaling pathway 703 0.373 0.962 1.00 0.100 None 1.000 15 3 1994 2016
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		P43246 mutS homolog 2 Nucleic acid binding 490 0.406 0.808 0.90 0.100 None 1.000 15 0 1995 2019
Entrez Id: 5664
Gene Symbol: PSEN2
PSEN2 		P49810 presenilin 2 Enzyme 146 0.550 0.654 5.4E-04 0.100 None 1.000 15 0 1997 2017
Entrez Id: 6598
Gene Symbol: SMARCB1
SMARCB1 		Q12824 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 Nucleic acid binding 448 0.434 0.846 1.00 0.100 None 1.000 15 0 2005 2018
Entrez Id: 112476
Gene Symbol: PRRT2
PRRT2 		Q7Z6L0 proline rich transmembrane protein 2 353 0.448 0.808 0.58 0.100 None 1.000 14 0 1999 2016
Entrez Id: 7428
Gene Symbol: VHL
VHL 		P40337 von Hippel-Lindau tumor suppressor Enzyme 372 0.443 0.846 8.0E-02 0.100 None 1.000 14 0 1995 2018
Entrez Id: 3949
Gene Symbol: LDLR
LDLR 		P01130 low density lipoprotein receptor 336 0.449 0.885 9.8E-24 0.100 None 1.000 13 1 1974 2014
Entrez Id: 10133
Gene Symbol: OPTN
OPTN 		Q96CV9 optineurin 136 0.548 0.808 5.9E-18 0.100 None 1.000 12 1 2003 2019
Entrez Id: 846
Gene Symbol: CASR
CASR 		P41180 calcium sensing receptor G-protein coupled receptor 517 0.410 0.846 4.7E-02 0.100 None 1.000 12 0 1998 2017
Entrez Id: 2706
Gene Symbol: GJB2
GJB2 		P29033 gap junction protein beta 2 Cell-cell junction 392 0.441 0.846 6.6E-16 0.100 None 1.000 11 1 1998 2019
Entrez Id: 4023
Gene Symbol: LPL
LPL 		P06858 lipoprotein lipase Enzyme 290 0.474 0.808 1.3E-09 0.100 None 0.909 11 0 1985 2017
Entrez Id: 4360
Gene Symbol: MRC1
MRC1 		P22897 mannose receptor C-type 1 431 0.413 0.846 0.94 0.100 None 1.000 11 0 1996 2014
Entrez Id: 6390
Gene Symbol: SDHB
SDHB 		P21912 succinate dehydrogenase complex iron sulfur subunit B Enzyme 316 0.474 0.846 2.4E-04 0.100 None 0.900 10 0 2002 2018
Entrez Id: 7253
Gene Symbol: TSHR
TSHR 		P16473 thyroid stimulating hormone receptor G-protein coupled receptor 250 0.486 0.808 3.0E-15 0.100 None 1.000 10 3 1997 2017
Entrez Id: 7389
Gene Symbol: UROD
UROD 		P06132 uroporphyrinogen decarboxylase 166 0.521 0.769 1.3E-08 0.100 None 0.900 10 0 1985 2012
Entrez Id: 8878
Gene Symbol: SQSTM1
SQSTM1 		Q13501 sequestosome 1 470 0.428 0.885 8.6E-04 0.100 None 1.000 10 0 2002 2019
Entrez Id: 335
Gene Symbol: APOA1
APOA1 		P02647 apolipoprotein A1 416 0.429 0.885 5.5E-04 0.090 None 0.889 9 0 1986 2018
Entrez Id: 4000
Gene Symbol: LMNA
LMNA 		P02545 lamin A/C 824 0.384 0.885 1.00 0.090 None 1.000 9 1 2002 2018
Entrez Id: 64127
Gene Symbol: NOD2
NOD2 		Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 434 0.423 0.923 2.0E-30 0.090 None 1.000 9 2 2002 2018
Entrez Id: 6440
Gene Symbol: SFTPC
SFTPC 		P11686 surfactant protein C 132 0.556 0.692 7.5E-04 0.090 None 1.000 9 0 2001 2015
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1 		P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1018 0.333 0.923 1.1E-03 0.080 None 0.875 8 0 1996 2019