Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 695
Gene Symbol: BTK
BTK
Q06187 Bruton tyrosine kinase Kinase 290 0.464 0.808 1.00 0.100 None 0 0
Entrez Id: 4522
Gene Symbol: MTHFD1
MTHFD1
P11586 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Enzyme 121 0.554 0.769 4.5E-03 0.100 None 0 0
Entrez Id: 3673
Gene Symbol: ITGA2
ITGA2
P17301 integrin subunit alpha 2 166 0.522 0.731 6.3E-11 0.010 None 1.000 1 0 1993 1993
Entrez Id: 3627
Gene Symbol: CXCL10
CXCL10
P02778 C-X-C motif chemokine ligand 10 Signaling 631 0.378 0.885 0.37 0.010 None 1.000 1 0 2003 2003
Entrez Id: 5530
Gene Symbol: PPP3CA
PPP3CA
Q08209 protein phosphatase 3 catalytic subunit alpha 149 0.568 0.769 1.00 0.010 None 1.000 1 0 2004 2004
Entrez Id: 4210
Gene Symbol: MEFV
MEFV
O15553 MEFV innate immuity regulator, pyrin 410 0.440 0.885 1.0E-14 0.010 None 1.000 1 0 2006 2006
Entrez Id: 4142
Gene Symbol: MAS1
MAS1
P04201 MAS1 proto-oncogene, G protein-coupled receptor G-protein coupled receptor 142 0.533 0.769 8.3E-05 0.010 None 1.000 1 0 2008 2008
Entrez Id: 54210
Gene Symbol: TREM1
TREM1
Q9NP99 triggering receptor expressed on myeloid cells 1 172 0.515 0.808 6.3E-03 0.010 None 1.000 1 0 2009 2009
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
P01579 interferon gamma 1519 0.288 0.962 0.47 0.300 None 1.000 1 0 2009 2009
Entrez Id: 9051
Gene Symbol: PSTPIP1
PSTPIP1
O43586 proline-serine-threonine phosphatase interacting protein 1 Cellular structure 54 0.650 0.577 2.5E-06 0.030 None 1.000 3 0 2006 2015
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.020 None 1.000 2 0 2017 2017
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.010 None 1.000 1 0 2017 2017
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
P08253 matrix metallopeptidase 2 Enzyme 1021 0.333 0.923 0.84 0.010 None 1.000 1 0 2017 2017
Entrez Id: 10299
Gene Symbol: MARCHF6
MARCHF6
O60337 membrane associated ring-CH-type finger 6 Enzyme 22 0.722 0.385 1.00 0.010 None 1.000 1 0 2017 2017
Entrez Id: 5069
Gene Symbol: PAPPA
PAPPA
Q13219 pappalysin 1 125 0.558 0.692 0.16 0.010 None 1.000 1 0 2017 2017
Entrez Id: 2737
Gene Symbol: GLI3
GLI3
P10071 GLI family zinc finger 3 400 0.436 0.846 1.00 0.010 None 1.000 1 0 2017 2017
Entrez Id: 7132
Gene Symbol: TNFRSF1A
TNFRSF1A
P19438 TNF receptor superfamily member 1A 487 0.409 0.923 0.99 0.020 None 1.000 2 0 2017 2018
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.310 None 1.000 2 0 2009 2018
Entrez Id: 7133
Gene Symbol: TNFRSF1B
TNFRSF1B
P20333 TNF receptor superfamily member 1B 417 0.425 0.885 0.50 0.010 None 1.000 1 0 2018 2018
Entrez Id: 90865
Gene Symbol: IL33
IL33
O95760 interleukin 33 487 0.409 0.885 8.3E-10 0.010 None 1.000 1 0 2018 2018
Entrez Id: 3579
Gene Symbol: CXCR2
CXCR2
P25025 C-X-C motif chemokine receptor 2 G-protein coupled receptor 335 0.445 0.923 1.4E-02 0.010 None 1.000 1 0 2018 2018
Entrez Id: 25870
Gene Symbol: SUMF2
SUMF2
Q8NBJ7 sulfatase modifying factor 2 59 0.623 0.769 1.0E-08 0.010 None 1.000 1 0 2018 2018
Entrez Id: 1401
Gene Symbol: CRP
CRP
P02741 C-reactive protein 1483 0.299 0.962 3.7E-03 0.070 None 1.000 7 0 2017 2019
Entrez Id: 47
Gene Symbol: ACLY
ACLY
P53396 ATP citrate lyase Enzyme 109 0.563 0.692 8.4E-02 0.020 None 1.000 2 0 2019 2019
Entrez Id: 84680
Gene Symbol: ACCS
ACCS
Q96QU6 1-aminocyclopropane-1-carboxylate synthase homolog (inactive) Enzyme 161 0.522 0.731 9.0E-07 0.010 None 1.000 1 0 2019 2019