Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 999
Gene Symbol: CDH1
CDH1
P12830 cadherin 1 322 0.432 0.759 0.11 0.800 definitive 0.926 144 48 1964 2018
Entrez Id: 1495
Gene Symbol: CTNNA1
CTNNA1
P35221 catenin alpha 1 cell adhesion molecule; cytoskeletal protein 45 0.636 0.483 0.98 0.320 0.500 2 0 2013 2016
Entrez Id: 324
Gene Symbol: APC
APC
P25054 APC, WNT signaling pathway regulator 462 0.397 0.828 1.00 0.310 1.000 1 0 2011 2011
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
P04818 thymidylate synthetase transferase 256 0.457 0.759 0.76 0.300 4 0 2005 2009
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 oxidoreductase 832 0.338 0.897 1.00 0.300 4 0 1999 2012
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
P04179 superoxide dismutase 2 oxidoreductase 488 0.396 0.897 0.16 0.300 4 0 2000 2014
Entrez Id: 374
Gene Symbol: AREG
AREG
P15514 amphiregulin signaling molecule 135 0.525 0.690 0.46 0.300 3 0 2005 2006
Entrez Id: 387
Gene Symbol: RHOA
RHOA
P61586 ras homolog family member A enzyme modulator 96 0.565 0.586 0.86 0.300 3 0 2005 2014
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1035 0.312 0.931 0.13 0.300 3 0 2005 2012
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 650 0.352 0.862 1.8E-03 0.300 3 0 2005 2012
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor 892 0.325 0.862 0.50 0.300 3 0 2005 2012
Entrez Id: 8289
Gene Symbol: ARID1A
ARID1A
O14497 AT-rich interaction domain 1A 211 0.505 0.724 1.00 0.300 3 0 2012 2014
Entrez Id: 1806
Gene Symbol: DPYD
DPYD
Q12882 dihydropyrimidine dehydrogenase oxidoreductase 191 0.520 0.690 5.7E-22 0.300 3 0 2005 2008
Entrez Id: 7372
Gene Symbol: UMPS
UMPS
P11172 uridine monophosphate synthetase 83 0.598 0.483 1.1E-04 0.300 3 0 2006 2008
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
P37231 peroxisome proliferator activated receptor gamma nucleic acid binding; receptor; transcription factor 540 0.388 0.828 0.14 0.300 2 0 2005 2009
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 699 0.354 0.828 1.2E-09 0.300 2 0 2008 2012
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor signaling molecule 1640 0.263 0.966 0.80 0.300 2 0 1992 2005
Entrez Id: 1548
Gene Symbol: CYP2A6
CYP2A6
P11509 cytochrome P450 family 2 subfamily A member 6 116 0.546 0.690 6.5E-09 0.300 2 0 2002 2011
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase enzyme modulator 886 0.350 0.724 9.0E-04 0.300 2 0 2000 2001
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
P10145 C-X-C motif chemokine ligand 8 signaling molecule 758 0.342 0.862 0.300 2 0 2005 2005
Entrez Id: 759
Gene Symbol: CA1
CA1
P00915 carbonic anhydrase 1 35 0.672 0.379 6.6E-11 0.300 2 0 2005 2009
Entrez Id: 8000
Gene Symbol: PSCA
PSCA
O43653 prostate stem cell antigen 62 0.604 0.517 0.17 0.300 2 0 2008 2015
Entrez Id: 8314
Gene Symbol: BAP1
BAP1
Q92560 BRCA1 associated protein 1 hydrolase; protease 186 0.488 0.586 0.99 0.300 2 0 2015 2016
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.300 2 0 2012 2014
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
P09211 glutathione S-transferase pi 1 398 0.406 0.828 7.1E-02 0.300 2 0 2011 2011