Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1
Q13635 patched 1 604 0.398 0.885 1.00 0.190 None 1.000 9 0 2009 2018
Entrez Id: 51684
Gene Symbol: SUFU
SUFU
Q9UMX1 SUFU negative regulator of hedgehog signaling 272 0.493 0.769 1.00 0.110 None 1.000 1 0 2013 2013
Entrez Id: 8643
Gene Symbol: PTCH2
PTCH2
Q9Y6C5 patched 2 114 0.563 0.692 3.4E-16 0.100 None 0 0
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.070 None 0.857 7 0 2001 2018
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.040 None 1.000 4 0 2009 2018
Entrez Id: 107075310
Gene Symbol: MTCO2P12
MTCO2P12
MT-CO2 pseudogene 12 703 0.368 0.962 0.020 None 1.000 2 0 2015 2015
Entrez Id: 2735
Gene Symbol: GLI1
GLI1
P08151 GLI family zinc finger 1 369 0.431 0.846 7.7E-14 0.020 None 1.000 2 0 2009 2011
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.020 None 1.000 2 2 2017 2018
Entrez Id: 4513
Gene Symbol: COX2
COX2
P00403 cytochrome c oxidase subunit II Enzyme 875 0.352 0.962 0.020 None 1.000 2 0 2015 2015
Entrez Id: 7471
Gene Symbol: WNT1
WNT1
P04628 Wnt family member 1 Signaling 216 0.495 0.769 0.33 0.020 None 1.000 2 0 2011 2018
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.020 None 1.000 2 0 2015 2015
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 1044 0.327 0.923 0.98 0.020 None 1.000 2 0 2018 2019
Entrez Id: 5715
Gene Symbol: PSMD9
PSMD9
O00233 proteasome 26S subunit, non-ATPase 9 Enzyme modulator 344 0.435 0.846 4.9E-06 0.010 None 1.000 1 0 2009 2009
Entrez Id: 5925
Gene Symbol: RB1
RB1
P06400 RB transcriptional corepressor 1 Nucleic acid binding 339 0.444 0.885 1.00 0.010 None 1.000 1 0 2009 2009
Entrez Id: 5602
Gene Symbol: MAPK10
MAPK10
P53779 mitogen-activated protein kinase 10 Kinase 75 0.606 0.692 0.28 0.010 None 1.000 1 0 2019 2019
Entrez Id: 5266
Gene Symbol: PI3
PI3
P19957 peptidase inhibitor 3 Enzyme modulator 92 0.570 0.692 0.17 0.010 None 1.000 1 0 1996 1996
Entrez Id: 6121
Gene Symbol: RPE65
RPE65
Q16518 retinoid isomerohydrolase RPE65 Enzyme 431 0.417 0.808 6.5E-14 0.010 None 1.000 1 0 2019 2019
Entrez Id: 5111
Gene Symbol: PCNA
PCNA
P12004 proliferating cell nuclear antigen Nucleic acid binding 581 0.382 0.846 0.98 0.010 None 1.000 1 0 2017 2017
Entrez Id: 644914
Gene Symbol: H3P16
H3P16
H3 histone pseudogene 16 23 0.705 0.346 0.010 None 1.000 1 0 2009 2009
Entrez Id: 9338
Gene Symbol: TCEAL1
TCEAL1
Q15170 transcription elongation factor A like 1 Transcription factor 25 0.700 0.346 0.59 0.010 None 1.000 1 0 2009 2009
Entrez Id: 92140
Gene Symbol: MTDH
MTDH
Q86UE4 metadherin 200 0.491 0.769 0.33 0.010 None 1.000 1 0 2017 2017
Entrez Id: 8626
Gene Symbol: TP63
TP63
Q9H3D4 tumor protein p63 Transcription factor 816 0.362 0.769 1.00 0.010 None 1.000 1 0 2019 2019
Entrez Id: 860
Gene Symbol: RUNX2
RUNX2
Q13950 RUNX family transcription factor 2 Transcription factor 405 0.437 0.846 0.95 0.010 None 1.000 1 0 2017 2017
Entrez Id: 836
Gene Symbol: CASP3
CASP3
P42574 caspase 3 Enzyme 819 0.351 0.923 0.10 0.010 None 1.000 1 0 2018 2018
Entrez Id: 7976
Gene Symbol: FZD3
FZD3
Q9NPG1 frizzled class receptor 3 G-protein coupled receptor 39 0.659 0.577 4.4E-04 0.010 None 1.000 1 0 2019 2019