Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7920
Gene Symbol: ABHD16A
ABHD16A
O95870 abhydrolase domain containing 16A Enzyme 10 0.861 0.269 0.47 0.010 None 1.000 1 0 2010 2010
Entrez Id: 60
Gene Symbol: ACTB
ACTB
P60709 actin beta Cellular structure 1110 0.325 0.923 0.99 0.030 None 1.000 3 0 1997 2014
Entrez Id: 11093
Gene Symbol: ADAMTS13
ADAMTS13
Q76LX8 ADAM metallopeptidase with thrombospondin type 1 motif 13 Enzyme 229 0.496 0.769 5.1E-15 0.010 None 1.000 1 0 2019 2019
Entrez Id: 177
Gene Symbol: AGER
AGER
Q15109 advanced glycosylation end-product specific receptor Receptor 450 0.420 0.885 6.4E-16 0.010 None 1.000 1 0 2019 2019
Entrez Id: 213
Gene Symbol: ALB
ALB
P02768 albumin Transporter 1198 0.317 0.962 0.64 0.030 None 1.000 3 0 2013 2019
Entrez Id: 199
Gene Symbol: AIF1
AIF1
P55008 allograft inflammatory factor 1 Calcium-binding protein 166 0.521 0.808 1.9E-06 0.010 None 1.000 1 0 2013 2013
Entrez Id: 2
Gene Symbol: A2M
A2M
P01023 alpha-2-macroglobulin Enzyme modulator 147 0.529 0.769 4.5E-11 0.010 None < 0.001 1 0 1999 1999
Entrez Id: 314
Gene Symbol: AOC2
AOC2
O75106 amine oxidase copper containing 2 37 0.674 0.654 3.3E-15 0.010 None 1.000 1 0 2015 2015
Entrez Id: 8639
Gene Symbol: AOC3
AOC3
Q16853 amine oxidase copper containing 3 106 0.561 0.769 6.3E-11 0.010 None 1.000 1 0 2015 2015
Entrez Id: 351
Gene Symbol: APP
APP
P05067 amyloid beta precursor protein Enzyme modulator 485 0.422 0.846 4.7E-02 0.100 None 0.970 33 3 1995 2019
Entrez Id: 325
Gene Symbol: APCS
APCS
P02743 amyloid P component, serum 141 0.531 0.808 3.2E-02 0.020 None 1.000 2 0 2016 2018
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme Enzyme 1082 0.328 0.923 1.0E-37 0.010 None 1.000 1 0 2011 2011
Entrez Id: 183
Gene Symbol: AGT
AGT
P01019 angiotensinogen Enzyme modulator 765 0.367 0.923 5.0E-08 0.010 None 1.000 1 1 2019 2019
Entrez Id: 335
Gene Symbol: APOA1
APOA1
P02647 apolipoprotein A1 416 0.429 0.885 5.5E-04 0.010 None 1.000 1 0 2016 2016
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.100 None 0.897 78 2 1995 2019
Entrez Id: 240
Gene Symbol: ALOX5
ALOX5
P09917 arachidonate 5-lipoxygenase Enzyme 342 0.447 0.885 1.2E-06 0.010 None 1.000 1 0 2014 2014
Entrez Id: 7917
Gene Symbol: BAG6
BAG6
P46379 BAG cochaperone 6 Enzyme modulator 40 0.674 0.615 1.00 0.010 None 1.000 1 0 2010 2010
Entrez Id: 8553
Gene Symbol: BHLHE40
BHLHE40
O14503 basic helix-loop-helix family member e40 Transcription factor 113 0.544 0.731 0.99 0.010 None 1.000 1 0 2016 2016
Entrez Id: 23621
Gene Symbol: BACE1
BACE1
P56817 beta-secretase 1 Enzyme 120 0.559 0.769 0.88 0.040 None 1.000 4 0 2007 2019
Entrez Id: 590
Gene Symbol: BCHE
BCHE
P06276 butyrylcholinesterase 392 0.447 0.923 1.1E-13 0.010 None < 0.001 1 0 1998 1998
Entrez Id: 968
Gene Symbol: CD68
CD68
P34810 CD68 molecule Transporter 452 0.408 0.808 1.4E-06 0.010 None 1.000 1 0 1997 1997
Entrez Id: 7122
Gene Symbol: CLDN5
CLDN5
O00501 claudin 5 Cell-cell junction 104 0.559 0.769 0.90 0.010 None 1.000 1 0 2018 2018
Entrez Id: 1191
Gene Symbol: CLU
CLU
P10909 clusterin 412 0.426 0.885 7.8E-05 0.060 None 1.000 6 1 2016 2019
Entrez Id: 2147
Gene Symbol: F2
F2
P00734 coagulation factor II, thrombin Enzyme 490 0.415 0.885 1.1E-03 0.010 None < 0.001 1 0 2007 2007
Entrez Id: 2162
Gene Symbol: F13A1
F13A1
P00488 coagulation factor XIII A chain Enzyme 117 0.575 0.731 5.3E-08 0.010 None 1.000 1 0 2019 2019