Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4041
Gene Symbol: LRP5
LRP5
O75197 LDL receptor related protein 5 283 0.485 0.846 0.51 0.060 None 1.000 6 2 2005 2018
Entrez Id: 50964
Gene Symbol: SOST
SOST
Q9BQB4 sclerostin 270 0.474 0.808 0.87 0.040 None 1.000 4 0 2012 2019
Entrez Id: 22943
Gene Symbol: DKK1
DKK1
O94907 dickkopf WNT signaling pathway inhibitor 1 372 0.439 0.885 0.17 0.030 None 1.000 3 0 2007 2020
Entrez Id: 10979
Gene Symbol: FERMT2
FERMT2
Q96AC1 fermitin family member 2 80 0.588 0.577 1.00 0.010 None 1.000 1 0 2019 2019
Entrez Id: 1277
Gene Symbol: COL1A1
COL1A1
P02452 collagen type I alpha 1 chain 487 0.430 0.808 1.00 0.010 None 1.000 1 0 2019 2019
Entrez Id: 1398
Gene Symbol: CRK
CRK
P46108 CRK proto-oncogene, adaptor protein 544 0.394 0.923 0.96 0.010 None 1.000 1 0 2019 2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
P35222 catenin beta 1 1368 0.303 0.885 1.00 0.010 None 1.000 1 0 2018 2018
Entrez Id: 257194
Gene Symbol: NEGR1
NEGR1
Q7Z3B1 neuronal growth regulator 1 40 0.695 0.577 0.99 0.010 None 1.000 1 0 2012 2012
Entrez Id: 286
Gene Symbol: ANK1
ANK1
P16157 ankyrin 1 166 0.540 0.885 1.00 0.010 None 1.000 1 0 2011 2011
Entrez Id: 3952
Gene Symbol: LEP
LEP
P41159 leptin 931 0.349 0.846 0.46 0.010 None 1.000 1 0 2019 2019
Entrez Id: 411
Gene Symbol: ARSB
ARSB
P15848 arylsulfatase B 96 0.595 0.692 7.0E-09 0.010 None 1.000 1 0 2018 2018
Entrez Id: 643911
Gene Symbol: CRNDE
CRNDE
colorectal neoplasia differentially expressed 70 0.597 0.615 0.010 None 1.000 1 0 2020 2020
Entrez Id: 6586
Gene Symbol: SLIT3
SLIT3
O75094 slit guidance ligand 3 62 0.623 0.615 0.75 0.010 None 1.000 1 0 2018 2018
Entrez Id: 692236
Gene Symbol: SNORD116@
SNORD116@
small nucleolar RNA, C/D box 116 cluster 33 0.705 0.692 0.010 None 1.000 1 0 2016 2016
Entrez Id: 2200
Gene Symbol: FBN1
FBN1
P35555 fibrillin 1 Calcium-binding protein 552 0.417 0.846 1.00 0.650 None 1.000 10 26 1992 2019
Entrez Id: 1545
Gene Symbol: CYP1B1
CYP1B1
Q16678 cytochrome P450 family 1 subfamily B member 1 Enzyme 304 0.457 0.769 2.2E-05 0.010 None 1.000 1 0 2013 2013
Entrez Id: 57154
Gene Symbol: SMURF1
SMURF1
Q9HCE7 SMAD specific E3 ubiquitin protein ligase 1 Enzyme 70 0.595 0.615 0.61 0.010 None 1.000 1 0 2017 2017
Entrez Id: 64750
Gene Symbol: SMURF2
SMURF2
Q9HAU4 SMAD specific E3 ubiquitin protein ligase 2 Enzyme 59 0.623 0.615 0.87 0.010 None 1.000 1 0 2017 2017
Entrez Id: 7173
Gene Symbol: TPO
TPO
P07202 thyroid peroxidase Enzyme 306 0.455 0.846 1.8E-21 0.010 None 1.000 1 0 2017 2017
Entrez Id: 8720
Gene Symbol: MBTPS1
MBTPS1
Q14703 membrane bound transcription factor peptidase, site 1 Enzyme 148 0.532 0.692 7.6E-09 0.010 None 1.000 1 0 2019 2019
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
Q96EB6 sirtuin 1 Epigenetic regulator 675 0.378 0.885 8.7E-02 0.010 None < 0.001 1 0 2017 2017
Entrez Id: 1268
Gene Symbol: CNR1
CNR1
P21554 cannabinoid receptor 1 G-protein coupled receptor 393 0.446 0.808 0.51 0.010 None 1.000 1 0 2018 2018
Entrez Id: 1903
Gene Symbol: S1PR3
S1PR3
Q99500 sphingosine-1-phosphate receptor 3 G-protein coupled receptor 47 0.638 0.654 4.7E-02 0.010 None 1.000 1 0 2019 2019
Entrez Id: 2149
Gene Symbol: F2R
F2R
P25116 coagulation factor II thrombin receptor G-protein coupled receptor 347 0.444 0.846 8.5E-03 0.010 None 1.000 1 0 2015 2015
Entrez Id: 799
Gene Symbol: CALCR
CALCR
P30988 calcitonin receptor G-protein coupled receptor 282 0.464 0.846 3.1E-09 0.010 None 1.000 1 0 2019 2019