Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1806
Gene Symbol: DPYD
DPYD
Q12882 dihydropyrimidine dehydrogenase Enzyme 249 0.493 0.846 3.4E-22 0.300 None 1.000 1 0 2001 2001
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
P10451 secreted phosphoprotein 1 824 0.353 0.885 2.1E-06 0.300 None 1.000 1 0 2002 2002
Entrez Id: 468
Gene Symbol: ATF4
ATF4
P18848 activating transcription factor 4 178 0.507 0.769 1.6E-02 0.010 None 1.000 1 0 2005 2005
Entrez Id: 6654
Gene Symbol: SOS1
SOS1
Q07889 SOS Ras/Rac guanine nucleotide exchange factor 1 Enzyme modulator 261 0.485 0.808 1.00 0.010 None 1.000 1 0 2005 2005
Entrez Id: 5923
Gene Symbol: RASGRF1
RASGRF1
Q13972 Ras protein specific guanine nucleotide releasing factor 1 Enzyme modulator 124 0.537 0.769 1.00 0.010 None 1.000 1 0 2005 2005
Entrez Id: 4548
Gene Symbol: MTR
MTR
Q99707 5-methyltetrahydrofolate-homocysteine methyltransferase 245 0.482 0.808 2.4E-12 0.300 None 1.000 1 0 2005 2005
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.300 None 1.000 1 0 2005 2005
Entrez Id: 6948
Gene Symbol: TCN2
TCN2
P20062 transcobalamin 2 104 0.578 0.615 1.0E-06 0.300 None 1.000 1 0 2005 2005
Entrez Id: 6342
Gene Symbol: SCP2
SCP2
P22307 sterol carrier protein 2 50 0.644 0.500 8.7E-07 0.300 None 1.000 1 0 2006 2006
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1
P09429 high mobility group box 1 Nucleic acid binding 724 0.368 0.923 0.82 0.020 None 1.000 2 0 2005 2007
Entrez Id: 134526
Gene Symbol: ACOT12
ACOT12
Q8WYK0 acyl-CoA thioesterase 12 Enzyme 9 0.805 0.192 2.7E-14 0.030 None 1.000 3 0 2002 2010
Entrez Id: 1282
Gene Symbol: COL4A1
COL4A1
P02462 collagen type IV alpha 1 chain 277 0.484 0.731 1.00 0.300 None 1.000 1 0 2010 2010
Entrez Id: 353
Gene Symbol: APRT
APRT
P07741 adenine phosphoribosyltransferase 384 0.423 0.846 5.5E-13 0.010 None 1.000 1 0 2011 2011
Entrez Id: 50515
Gene Symbol: CHST11
CHST11
Q9NPF2 carbohydrate sulfotransferase 11 Enzyme 36 0.682 0.500 0.41 0.010 None 1.000 1 0 2011 2011
Entrez Id: 1436
Gene Symbol: CSF1R
CSF1R
P07333 colony stimulating factor 1 receptor Kinase 356 0.448 0.808 0.13 0.300 None 1.000 1 0 2011 2011
Entrez Id: 3037
Gene Symbol: HAS2
HAS2
Q92819 hyaluronan synthase 2 85 0.588 0.692 0.99 0.010 None 1.000 1 0 2011 2011
Entrez Id: 4236
Gene Symbol: MFAP1
MFAP1
P55081 microfibril associated protein 1 Extracellular structure 357 0.431 0.846 0.80 0.010 None 1.000 1 0 2011 2011
Entrez Id: 6278
Gene Symbol: S100A7
S100A7
P31151 S100 calcium binding protein A7 Calcium-binding protein 119 0.546 0.769 0.45 0.010 None 1.000 1 0 2011 2011
Entrez Id: 1672
Gene Symbol: DEFB1
DEFB1
P60022 defensin beta 1 177 0.509 0.808 0.41 0.010 None 1.000 1 0 2011 2011
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.030 None 0.667 3 0 2005 2013
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
Q16552 interleukin 17A 1074 0.324 0.923 4.3E-02 0.010 None 1.000 1 0 2013 2013
Entrez Id: 4277
Gene Symbol: MICB
MICB
Q29980 MHC class I polypeptide-related sequence B 95 0.576 0.731 4.1E-05 0.010 None 1.000 1 0 2015 2015
Entrez Id: 4439
Gene Symbol: MSH5
MSH5
O43196 mutS homolog 5 Nucleic acid binding 51 0.641 0.692 3.2E-11 0.010 None 1.000 1 0 2015 2015
Entrez Id: 56658
Gene Symbol: TRIM39
TRIM39
Q9HCM9 tripartite motif containing 39 9 0.792 0.462 0.99 0.010 None 1.000 1 0 2015 2015
Entrez Id: 79897
Gene Symbol: RPP21
RPP21
Q9H633 ribonuclease P/MRP subunit p21 Enzyme 5 0.839 0.269 4.9E-05 0.010 None 1.000 1 0 2015 2015