Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 207
Gene Symbol: AKT1
AKT1
P31749 AKT serine/threonine kinase 1 Kinase 1011 0.311 0.962 0.98 0.010 None 1.000 1 0 2018 2018
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
P01911 major histocompatibility complex, class II, DR beta 1 Immune response 839 0.333 0.923 1.1E-03 0.010 None 1.000 1 0 2006 2006
Entrez Id: 4609
Gene Symbol: MYC
MYC
P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 747 0.344 0.923 1.00 0.010 None 1.000 1 0 2010 2010
Entrez Id: 7421
Gene Symbol: VDR
VDR
P11473 vitamin D receptor Nuclear receptor 757 0.352 0.885 1.7E-05 0.010 None 1.000 1 0 2007 2007
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 698 0.358 0.885 2.9E-02 0.020 None 1.000 2 0 2007 2007
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
P11362 fibroblast growth factor receptor 1 Kinase 470 0.362 0.885 1.00 0.010 None 1.000 1 0 2005 2005
Entrez Id: 355
Gene Symbol: FAS
FAS
P25445 Fas cell surface death receptor 526 0.372 0.923 0.81 0.010 None 1.000 1 0 1998 1998
Entrez Id: 5595
Gene Symbol: MAPK3
MAPK3
P27361 mitogen-activated protein kinase 3 Kinase 577 0.379 0.885 3.7E-02 0.010 None 1.000 1 0 2018 2018
Entrez Id: 4000
Gene Symbol: LMNA
LMNA
P02545 lamin A/C 401 0.384 0.885 1.00 0.010 None 1.000 1 0 2007 2007
Entrez Id: 7291
Gene Symbol: TWIST1
TWIST1
Q15672 twist family bHLH transcription factor 1 Transcription factor 436 0.397 0.846 0.34 0.010 None 1.000 1 0 2019 2019
Entrez Id: 5573
Gene Symbol: PRKAR1A
PRKAR1A
P10644 protein kinase cAMP-dependent type I regulatory subunit alpha 384 0.401 0.846 1.00 0.010 None 1.000 1 0 2010 2010
Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
T cell receptor beta variable 20/OR9-2 (non-functional) 456 0.403 0.923 0.010 None 1.000 1 0 2005 2005
Entrez Id: 2147
Gene Symbol: F2
F2
P00734 coagulation factor II, thrombin Enzyme 393 0.415 0.885 1.1E-03 0.010 None 1.000 1 0 2017 2017
Entrez Id: 2152
Gene Symbol: F3
F3
P13726 coagulation factor III, tissue factor Receptor 418 0.415 0.846 1.9E-02 0.010 None 1.000 1 0 2008 2008
Entrez Id: 4684
Gene Symbol: NCAM1
NCAM1
P13591 neural cell adhesion molecule 1 416 0.415 0.885 1.00 0.010 None 1.000 1 0 2019 2019
Entrez Id: 353
Gene Symbol: APRT
APRT
P07741 adenine phosphoribosyltransferase 370 0.423 0.846 5.5E-13 0.010 None 1.000 1 0 2013 2013
Entrez Id: 8878
Gene Symbol: SQSTM1
SQSTM1
Q13501 sequestosome 1 339 0.428 0.885 8.6E-04 0.010 None 1.000 1 0 2018 2018
Entrez Id: 4236
Gene Symbol: MFAP1
MFAP1
P55081 microfibril associated protein 1 Extracellular structure 357 0.431 0.846 0.80 0.010 None 1.000 1 0 2013 2013
Entrez Id: 5578
Gene Symbol: PRKCA
PRKCA
P17252 protein kinase C alpha Kinase 323 0.440 0.846 0.37 0.010 None 1.000 1 0 2010 2010
Entrez Id: 3684
Gene Symbol: ITGAM
ITGAM
P11215 integrin subunit alpha M 323 0.443 0.808 3.3E-11 0.010 None 1.000 1 0 2010 2010
Entrez Id: 112476
Gene Symbol: PRRT2
PRRT2
Q7Z6L0 proline rich transmembrane protein 2 297 0.448 0.808 0.58 0.010 None 1.000 1 0 2010 2010
Entrez Id: 2185
Gene Symbol: PTK2B
PTK2B
Q14289 protein tyrosine kinase 2 beta Kinase 298 0.448 0.808 0.94 0.010 None 1.000 1 0 2018 2018
Entrez Id: 7161
Gene Symbol: TP73
TP73
O15350 tumor protein p73 Transcription factor 275 0.449 0.808 1.00 0.010 None 1.000 1 0 2017 2017
Entrez Id: 5579
Gene Symbol: PRKCB
PRKCB
P05771 protein kinase C beta Kinase 288 0.453 0.885 1.00 0.010 None 1.000 1 0 2010 2010
Entrez Id: 10657
Gene Symbol: KHDRBS1
KHDRBS1
Q07666 KH RNA binding domain containing, signal transduction associated 1 Nucleic acid binding 288 0.457 0.846 0.99 0.010 None 1.000 1 0 2018 2018