Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.010 None 1.000 1 0 2012 2012
Entrez Id: 3458
Gene Symbol: IFNG
IFNG 		P01579 interferon gamma 1519 0.288 0.962 0.47 0.300 None 0 0
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.020 None 1.000 2 0 2010 2019
Entrez Id: 207
Gene Symbol: AKT1
AKT1 		P31749 AKT serine/threonine kinase 1 Kinase 1250 0.311 0.962 0.98 0.010 None 1.000 1 0 2011 2011
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.030 None 1.000 3 0 2011 2016
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1 		P28482 mitogen-activated protein kinase 1 Kinase 1059 0.330 0.923 1.00 0.020 None 1.000 2 0 2011 2018
Entrez Id: 2475
Gene Symbol: MTOR
MTOR 		P42345 mechanistic target of rapamycin kinase Kinase 960 0.343 0.885 1.00 0.060 None 1.000 6 0 2009 2019
Entrez Id: 595
Gene Symbol: CCND1
CCND1 		P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.020 None 1.000 2 0 2011 2011
Entrez Id: 2048
Gene Symbol: EPHB2
EPHB2 		P29323 EPH receptor B2 Kinase 649 0.374 0.846 1.00 0.020 None 1.000 2 0 2011 2018
Entrez Id: 3342
Gene Symbol: HTC2
HTC2 		hypertrichosis 2 (generalized, congenital) 511 0.392 0.808 0.010 None 1.000 1 0 2004 2004
Entrez Id: 5894
Gene Symbol: RAF1
RAF1 		P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 470 0.418 0.885 0.85 0.020 None 1.000 2 0 2011 2011
Entrez Id: 351
Gene Symbol: APP
APP 		P05067 amyloid beta precursor protein Enzyme modulator 485 0.422 0.846 4.7E-02 0.010 None 1.000 1 0 2009 2009
Entrez Id: 4982
Gene Symbol: TNFRSF11B
TNFRSF11B 		O00300 TNF receptor superfamily member 11b 443 0.422 0.808 0.16 0.010 None 1.000 1 0 2013 2013
Entrez Id: 5715
Gene Symbol: PSMD9
PSMD9 		O00233 proteasome 26S subunit, non-ATPase 9 Enzyme modulator 344 0.435 0.846 4.9E-06 0.010 None 1.000 1 0 2011 2011
Entrez Id: 51014
Gene Symbol: TMED7
TMED7 		Q86XR7 Q9Y3B3 transmembrane p24 trafficking protein 7 Transporter 336 0.436 0.808 0.48 0.010 None 1.000 1 0 2011 2011
Entrez Id: 3429
Gene Symbol: IFI27
IFI27 		P40305 interferon alpha inducible protein 27 332 0.437 0.769 1.1E-02 0.010 None 1.000 1 0 2011 2011
Entrez Id: 100302736
Gene Symbol: TMED7-TICAM2
TMED7-TICAM2 		Q86XR7 Q9Y3B3 TMED7-TICAM2 readthrough 329 0.438 0.769 2.6E-03 0.010 None 1.000 1 0 2011 2011
Entrez Id: 353376
Gene Symbol: TICAM2
TICAM2 		Q86XR7 Q9Y3B3 toll like receptor adaptor molecule 2 332 0.438 0.769 2.6E-03 0.010 None 1.000 1 0 2011 2011
Entrez Id: 7249
Gene Symbol: TSC2
TSC2 		P49815 TSC complex subunit 2 Enzyme modulator 410 0.439 0.808 1.00 0.800 None 0.992 121 253 1995 2019
Entrez Id: 7248
Gene Symbol: TSC1
TSC1 		Q92574 TSC complex subunit 1 391 0.440 0.808 1.00 0.100 None 1.000 30 1 1995 2019
Entrez Id: 10671
Gene Symbol: DCTN6
DCTN6 		O00399 dynactin subunit 6 Cellular structure 315 0.442 0.769 5.6E-02 0.010 None 1.000 1 0 2011 2011
Entrez Id: 10534
Gene Symbol: ZNRD2
ZNRD2 		O60232 zinc ribbon domain containing 2 311 0.443 0.769 1.8E-07 0.010 None 1.000 1 0 2011 2011
Entrez Id: 115482696
Gene Symbol: H3P23
H3P23 		H3 histone pseudogene 23 310 0.443 0.769 0.010 None 1.000 1 0 2011 2011
Entrez Id: 6037
Gene Symbol: RNASE3
RNASE3 		P12724 ribonuclease A family member 3 207 0.490 0.808 0.020 None 1.000 2 0 2011 2011
Entrez Id: 5310
Gene Symbol: PKD1
PKD1 		P98161 polycystin 1, transient receptor potential channel interacting 217 0.493 0.769 1.00 0.030 None 1.000 3 17 2000 2015