Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
P29474 nitric oxide synthase 3 706 0.378 0.885 6.7E-07 0.040 None 1.000 4 1 1999 2017
Entrez Id: 324
Gene Symbol: APC
APC
P25054 APC regulator of WNT signaling pathway 703 0.373 0.962 1.00 0.030 None 1.000 3 1 2001 2019
Entrez Id: 1440
Gene Symbol: CSF3
CSF3
P09919 colony stimulating factor 3 687 0.377 0.885 0.38 0.010 None 1.000 1 0 2017 2017
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
P05305 endothelin 1 Signaling 679 0.380 0.846 0.46 0.010 None 1.000 1 0 2017 2017
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1
P09601 heme oxygenase 1 666 0.381 0.923 9.7E-03 0.020 None 1.000 2 0 2008 2012
Entrez Id: 2056
Gene Symbol: EPO
EPO
P01588 erythropoietin 646 0.381 0.885 1.1E-02 0.040 None 1.000 4 0 2017 2019
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
O60674 Janus kinase 2 Kinase 644 0.385 0.885 0.65 0.080 None 1.000 8 2 2008 2019
Entrez Id: 3596
Gene Symbol: IL13
IL13
P35225 interleukin 13 587 0.386 0.846 1.4E-02 0.010 None 1.000 1 0 2010 2010
Entrez Id: 5340
Gene Symbol: PLG
PLG
P00747 plasminogen Enzyme 586 0.389 0.923 1.0E-02 0.030 None 1.000 3 1 1998 2018
Entrez Id: 4153
Gene Symbol: MBL2
MBL2
P11226 mannose binding lectin 2 Receptor 563 0.390 0.846 2.7E-03 0.020 None 1.000 2 0 2018 2019
Entrez Id: 7291
Gene Symbol: TWIST1
TWIST1
Q15672 twist family bHLH transcription factor 1 Transcription factor 559 0.397 0.846 0.34 0.010 None 1.000 1 0 2019 2019
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1
P19838 nuclear factor kappa B subunit 1 Transcription factor 551 0.396 0.923 1.00 0.010 None 1.000 1 1 2013 2013
Entrez Id: 929
Gene Symbol: CD14
CD14
P08571 CD14 molecule 551 0.392 0.885 4.9E-05 0.010 None 1.000 1 0 2019 2019
Entrez Id: 5741
Gene Symbol: PTH
PTH
P01270 parathyroid hormone 528 0.397 0.846 1.2E-02 0.020 None < 0.001 2 0 2015 2017
Entrez Id: 1351
Gene Symbol: COX8A
COX8A
P10176 cytochrome c oxidase subunit 8A Enzyme 526 0.400 0.846 0.12 0.100 None 0.947 19 0 1996 2018
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 519 0.410 0.885 1.7E-05 0.030 None 1.000 3 0 2018 2019
Entrez Id: 238
Gene Symbol: ALK
ALK
Q9UM73 ALK receptor tyrosine kinase Kinase 519 0.396 0.846 3.2E-06 0.020 None 0.500 2 0 2014 2017
Entrez Id: 1234
Gene Symbol: CCR5
CCR5
P51681 C-C motif chemokine receptor 5 (gene/pseudogene) G-protein coupled receptor 508 0.398 0.885 4.3E-10 0.010 None 1.000 1 0 2009 2009
Entrez Id: 7450
Gene Symbol: VWF
VWF
P04275 von Willebrand factor Enzyme modulator 498 0.408 0.885 3.2E-25 0.200 None 1.000 19 1 1999 2019
Entrez Id: 5444
Gene Symbol: PON1
PON1
P27169 paraoxonase 1 496 0.409 0.885 9.8E-11 0.020 None 1.000 2 1 2009 2018
Entrez Id: 2147
Gene Symbol: F2
F2
P00734 coagulation factor II, thrombin Enzyme 490 0.415 0.885 1.1E-03 0.500 None 0.937 143 10 1997 2019
Entrez Id: 811
Gene Symbol: CALR
CALR
P27797 calreticulin Calcium-binding protein 487 0.413 0.923 0.89 0.030 None 1.000 3 0 2017 2019
Entrez Id: 351
Gene Symbol: APP
APP
P05067 amyloid beta precursor protein Enzyme modulator 485 0.422 0.846 4.7E-02 0.010 None 1.000 1 0 2017 2017
Entrez Id: 4314
Gene Symbol: MMP3
MMP3
P08254 matrix metallopeptidase 3 Enzyme 473 0.408 0.885 5.7E-15 0.010 None 1.000 1 1 2009 2009
Entrez Id: 3240
Gene Symbol: HP
HP
P00738 haptoglobin Enzyme 464 0.412 0.885 1.7E-05 0.010 None 1.000 1 0 2005 2005