Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 23435
Gene Symbol: TARDBP
TARDBP 		Q13148 TAR DNA binding protein 245 0.493 0.808 0.99 0.100 None 1.000 38 0 2007 2020
Entrez Id: 2521
Gene Symbol: FUS
FUS 		P35637 FUS RNA binding protein Nucleic acid binding 301 0.470 0.846 1.00 0.100 None 1.000 16 0 2010 2017
Entrez Id: 10133
Gene Symbol: OPTN
OPTN 		Q96CV9 optineurin 136 0.548 0.808 5.9E-18 0.090 None 1.000 9 0 2011 2019
Entrez Id: 3483
Gene Symbol: IGFALS
IGFALS 		P35858 insulin like growth factor binding protein acid labile subunit Receptor 203 0.511 0.846 5.4E-11 0.090 None 1.000 9 1 1997 2018
Entrez Id: 283
Gene Symbol: ANG
ANG 		P03950 angiogenin 185 0.511 0.769 0.29 0.070 None 1.000 7 0 2008 2019
Entrez Id: 7415
Gene Symbol: VCP
VCP 		P55072 valosin containing protein 376 0.469 0.923 1.00 0.070 None 1.000 7 0 2012 2015
Entrez Id: 348
Gene Symbol: APOE
APOE 		P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.050 None 1.000 5 0 1995 2011
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.210 None 1.000 4 0 2001 2008
Entrez Id: 23025
Gene Symbol: UNC13A
UNC13A 		Q9UPW8 unc-13 homolog A 41 0.705 0.423 1.00 0.130 None 1.000 4 1 2009 2019
Entrez Id: 9782
Gene Symbol: MATR3
MATR3 		P43243 matrin 3 92 0.631 0.538 1.00 0.030 None 1.000 3 0 2016 2018
Entrez Id: 1804
Gene Symbol: DPP6
DPP6 		P42658 dipeptidyl peptidase like 6 Enzyme 71 0.603 0.692 0.34 0.030 None 1.000 3 1 2009 2012
Entrez Id: 3077
Gene Symbol: HFE
HFE 		Q30201 homeostatic iron regulator 415 0.436 0.846 2.6E-08 0.030 None 1.000 3 2 2011 2014
Entrez Id: 2891
Gene Symbol: GRIA2
GRIA2 		P42262 glutamate ionotropic receptor AMPA type subunit 2 Ion channel 110 0.573 0.692 1.00 0.030 None 1.000 3 0 2006 2010
Entrez Id: 22920
Gene Symbol: KIFAP3
KIFAP3 		Q92845 kinesin associated protein 3 Cellular structure 19 0.760 0.346 1.6E-05 0.030 None 1.000 3 1 2009 2012
Entrez Id: 6648
Gene Symbol: SOD2
SOD2 		P04179 superoxide dismutase 2 Enzyme 668 0.379 0.923 0.15 0.210 None 1.000 3 0 1998 2005
Entrez Id: 2912
Gene Symbol: GRM2
GRM2 		Q14416 glutamate metabotropic receptor 2 G-protein coupled receptor 104 0.582 0.577 0.12 0.030 None 1.000 3 0 2006 2010
Entrez Id: 5445
Gene Symbol: PON2
PON2 		Q15165 paraoxonase 2 117 0.566 0.808 5.4E-05 0.020 None 1.000 2 1 2010 2012
Entrez Id: 29110
Gene Symbol: TBK1
TBK1 		Q9UHD2 TANK binding kinase 1 Kinase 207 0.513 0.846 7.5E-02 0.020 None 1.000 2 0 2017 2018
Entrez Id: 2066
Gene Symbol: ERBB4
ERBB4 		Q15303 erb-b2 receptor tyrosine kinase 4 Kinase 317 0.455 0.846 1.00 0.110 None 1.000 2 1 2014 2017
Entrez Id: 5216
Gene Symbol: PFN1
PFN1 		P07737 profilin 1 119 0.565 0.769 0.73 0.020 None 1.000 2 0 2013 2013
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.310 None 1.000 2 0 2002 2010
Entrez Id: 6638
Gene Symbol: SNRPN
SNRPN 		P63162 Q9Y675 small nuclear ribonucleoprotein polypeptide N Nucleic acid binding 183 0.538 0.731 4.3E-02 0.020 None 1.000 2 0 2012 2014
Entrez Id: 3297
Gene Symbol: HSF1
HSF1 		Q00613 heat shock transcription factor 1 Transcription factor 185 0.507 0.769 0.75 0.310 None 1.000 2 0 2013 2016
Entrez Id: 1509
Gene Symbol: CTSD
CTSD 		P07339 cathepsin D Enzyme 242 0.478 0.846 9.2E-04 0.310 None 1.000 2 0 2002 2019
Entrez Id: 1191
Gene Symbol: CLU
CLU 		P10909 clusterin 412 0.426 0.885 7.8E-05 0.310 None 1.000 2 0 1999 2002