Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
P42345 mechanistic target of rapamycin kinase Kinase 960 0.343 0.885 1.00 0.020 None 1.000 2 0 2014 2015
Entrez Id: 3952
Gene Symbol: LEP
LEP
P41159 leptin 931 0.349 0.846 0.46 0.010 None 1.000 1 0 2018 2018
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
P01112 HRas proto-oncogene, GTPase Enzyme modulator 698 0.378 0.885 8.0E-02 0.010 None 1.000 1 1 2016 2016
Entrez Id: 5111
Gene Symbol: PCNA
PCNA
P12004 proliferating cell nuclear antigen Nucleic acid binding 581 0.382 0.846 0.98 0.010 None 1.000 1 0 1995 1995
Entrez Id: 6750
Gene Symbol: SST
SST
P61278 somatostatin Signaling 535 0.399 0.885 0.34 0.010 None 1.000 1 0 2019 2019
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
P38936 cyclin dependent kinase inhibitor 1A 490 0.403 0.769 1.9E-03 0.100 None 0 0
Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
P46527 cyclin dependent kinase inhibitor 1B 454 0.409 0.769 0.62 0.100 None 0 0
Entrez Id: 1030
Gene Symbol: CDKN2B
CDKN2B
P42772 cyclin dependent kinase inhibitor 2B 440 0.417 0.769 7.3E-03 0.100 None 0 0
Entrez Id: 1803
Gene Symbol: DPP4
DPP4
P27487 dipeptidyl peptidase 4 Enzyme 451 0.420 0.808 7.3E-09 0.010 None 1.000 1 0 2015 2015
Entrez Id: 1387
Gene Symbol: CREBBP
CREBBP
Q92793 CREB binding protein 438 0.428 0.808 1.00 0.010 None < 0.001 1 0 2019 2019
Entrez Id: 2641
Gene Symbol: GCG
GCG
P01275 glucagon 441 0.431 0.885 3.5E-02 0.050 None 1.000 5 0 2005 2019
Entrez Id: 3643
Gene Symbol: INSR
INSR
P06213 insulin receptor Kinase 452 0.432 0.846 3.6E-05 0.130 None 1.000 3 0 2004 2015
Entrez Id: 4221
Gene Symbol: MEN1
MEN1
O00255 menin 1 364 0.444 0.808 1.00 0.120 None 1.000 2 0 2015 2016
Entrez Id: 3630
Gene Symbol: INS
INS
P01308 insulin 405 0.445 0.923 0.30 0.100 None 0 0
Entrez Id: 1028
Gene Symbol: CDKN1C
CDKN1C
P49918 cyclin dependent kinase inhibitor 1C 298 0.456 0.846 0.82 0.010 None 1.000 1 0 2005 2005
Entrez Id: 3172
Gene Symbol: HNF4A
HNF4A
P41235 hepatocyte nuclear factor 4 alpha Nuclear receptor 340 0.461 0.808 0.15 0.200 None 0.867 15 1 2007 2016
Entrez Id: 8085
Gene Symbol: KMT2D
KMT2D
O14686 lysine methyltransferase 2D 320 0.465 0.808 1.00 0.010 None 1.000 1 0 2018 2018
Entrez Id: 2740
Gene Symbol: GLP1R
GLP1R
P43220 glucagon like peptide 1 receptor G-protein coupled receptor 288 0.471 0.846 0.29 0.040 None 1.000 4 0 2017 2019
Entrez Id: 6833
Gene Symbol: ABCC8
ABCC8
Q09428 ATP binding cassette subfamily C member 8 Transporter 317 0.474 0.846 8.0E-24 0.200 None 0.952 21 1 1999 2020
Entrez Id: 6927
Gene Symbol: HNF1A
HNF1A
P20823 HNF1 homeobox A Nucleic acid binding 292 0.478 0.846 0.96 0.140 None 1.000 4 0 2013 2019
Entrez Id: 26291
Gene Symbol: FGF21
FGF21
Q9NSA1 fibroblast growth factor 21 Signaling 236 0.485 0.769 2.9E-02 0.010 None 1.000 1 0 2017 2017
Entrez Id: 7351
Gene Symbol: UCP2
UCP2
P55851 uncoupling protein 2 Transporter 235 0.493 0.808 1.5E-10 0.110 None 1.000 1 0 2008 2008
Entrez Id: 6566
Gene Symbol: SLC16A1
SLC16A1
P53985 solute carrier family 16 member 1 Transporter 195 0.499 0.846 7.4E-04 0.120 None 1.000 2 0 2009 2019
Entrez Id: 64324
Gene Symbol: NSD1
NSD1
Q96L73 nuclear receptor binding SET domain protein 1 Epigenetic regulator 247 0.505 0.769 1.00 0.120 None 1.000 2 1 2015 2019
Entrez Id: 1215
Gene Symbol: CMA1
CMA1
P23946 chymase 1 Enzyme 157 0.514 0.692 7.6E-09 0.010 None 1.000 1 0 2019 2019