Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
P01130 low density lipoprotein receptor 336 0.449 0.885 9.8E-24 0.200 None 1.000 11 0 1992 2016
Entrez Id: 335
Gene Symbol: APOA1
APOA1
P02647 apolipoprotein A1 416 0.429 0.885 5.5E-04 0.080 None 1.000 8 0 1986 2008
Entrez Id: 338
Gene Symbol: APOB
APOB
P04114 apolipoprotein B 339 0.453 0.808 1.9E-16 0.170 None 1.000 7 0 1988 2012
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.160 None 1.000 6 1 1997 2017
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
P29474 nitric oxide synthase 3 706 0.378 0.885 6.7E-07 0.050 None 1.000 5 1 2005 2017
Entrez Id: 19
Gene Symbol: ABCA1
ABCA1
O95477 ATP binding cassette subfamily A member 1 Transporter 291 0.467 0.846 1.5E-13 0.150 None 1.000 5 3 2002 2015
Entrez Id: 790
Gene Symbol: CAD
CAD
P27708 carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase Enzyme 249 0.482 0.846 1.00 0.050 None 0.800 5 0 2009 2019
Entrez Id: 4018
Gene Symbol: LPA
LPA
P08519 lipoprotein(a) Enzyme 340 0.444 0.769 6.6E-89 0.050 None 1.000 5 0 1994 2019
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.050 None 0.800 5 1 1997 2008
Entrez Id: 4023
Gene Symbol: LPL
LPL
P06858 lipoprotein lipase Enzyme 290 0.474 0.808 1.3E-09 0.040 None 1.000 4 0 1990 2006
Entrez Id: 1071
Gene Symbol: CETP
CETP
P11597 cholesteryl ester transfer protein 188 0.512 0.731 1.2E-23 0.040 None 1.000 4 1 2005 2016
Entrez Id: 6401
Gene Symbol: SELE
SELE
P16581 selectin E 327 0.447 0.808 7.9E-10 0.030 None 1.000 3 2 2000 2003
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
P13500 C-C motif chemokine ligand 2 Signaling 1157 0.321 0.962 0.61 0.030 None 1.000 3 1 2008 2015
Entrez Id: 7057
Gene Symbol: THBS1
THBS1
P07996 thrombospondin 1 480 0.407 0.885 1.00 0.030 None 1.000 3 1 2002 2004
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.030 None 1.000 3 1 2007 2017
Entrez Id: 186
Gene Symbol: AGTR2
AGTR2
P50052 angiotensin II receptor type 2 G-protein coupled receptor 229 0.496 0.808 8.2E-03 0.020 None 1.000 2 0 2005 2007
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
Q16552 interleukin 17A 1074 0.324 0.923 4.3E-02 0.020 None 1.000 2 0 2015 2015
Entrez Id: 26119
Gene Symbol: LDLRAP1
LDLRAP1
Q5SW96 low density lipoprotein receptor adaptor protein 1 Signaling 64 0.641 0.538 6.5E-06 0.120 None 1.000 2 0 2003 2005
Entrez Id: 345
Gene Symbol: APOC3
APOC3
P02656 apolipoprotein C3 153 0.531 0.731 1.0E-02 0.020 None 1.000 2 0 1986 1986
Entrez Id: 1535
Gene Symbol: CYBA
CYBA
P13498 cytochrome b-245 alpha chain 177 0.520 0.769 8.9E-06 0.020 None 1.000 2 0 2011 2014
Entrez Id: 368
Gene Symbol: ABCC6
ABCC6
O95255 ATP binding cassette subfamily C member 6 Transporter 181 0.540 0.654 5.6E-35 0.020 None 0.500 2 1 2002 2005
Entrez Id: 4205
Gene Symbol: MEF2A
MEF2A
Q02078 myocyte enhancer factor 2A Transcription factor 99 0.585 0.692 0.99 0.020 None 1.000 2 0 2013 2016
Entrez Id: 7804
Gene Symbol: LRP8
LRP8
Q14114 LDL receptor related protein 8 55 0.644 0.346 1.00 0.020 None 1.000 2 0 2007 2014
Entrez Id: 101054525
Gene Symbol: PGR-AS1
PGR-AS1
PGR antisense RNA 1 172 0.514 0.808 0.020 None 1.000 2 0 2005 2007
Entrez Id: 1586
Gene Symbol: CYP17A1
CYP17A1
P05093 cytochrome P450 family 17 subfamily A member 1 326 0.462 0.769 2.6E-04 0.020 None 1.000 2 0 2005 2015