Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
P01130 low density lipoprotein receptor 336 0.449 0.885 9.8E-24 0.200 None 1.000 11 0 1992 2016
Entrez Id: 338
Gene Symbol: APOB
APOB
P04114 apolipoprotein B 339 0.453 0.808 1.9E-16 0.170 None 1.000 7 0 1988 2012
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.160 None 1.000 6 1 1997 2017
Entrez Id: 19
Gene Symbol: ABCA1
ABCA1
O95477 ATP binding cassette subfamily A member 1 Transporter 291 0.467 0.846 1.5E-13 0.150 None 1.000 5 3 2002 2015
Entrez Id: 26119
Gene Symbol: LDLRAP1
LDLRAP1
Q5SW96 low density lipoprotein receptor adaptor protein 1 Signaling 64 0.641 0.538 6.5E-06 0.120 None 1.000 2 0 2003 2005
Entrez Id: 3990
Gene Symbol: LIPC
LIPC
P11150 lipase C, hepatic type Enzyme 120 0.585 0.654 3.3E-07 0.100 None 0 0
Entrez Id: 255738
Gene Symbol: PCSK9
PCSK9
Q8NBP7 proprotein convertase subtilisin/kexin type 9 Enzyme 257 0.482 0.808 2.7E-17 0.100 None 0 0
Entrez Id: 64241
Gene Symbol: ABCG8
ABCG8
Q9H221 ATP binding cassette subfamily G member 8 Transporter 116 0.573 0.538 2.4E-20 0.100 None 0 0
Entrez Id: 4000
Gene Symbol: LMNA
LMNA
P02545 lamin A/C 824 0.384 0.885 1.00 0.100 None 0 0
Entrez Id: 6403
Gene Symbol: SELP
SELP
P16109 selectin P 293 0.460 0.769 5.0E-32 0.100 None 0 1
Entrez Id: 64240
Gene Symbol: ABCG5
ABCG5
Q9H222 ATP binding cassette subfamily G member 5 Transporter 108 0.592 0.577 3.1E-21 0.100 None 0 0
Entrez Id: 10269
Gene Symbol: ZMPSTE24
ZMPSTE24
O75844 zinc metallopeptidase STE24 Enzyme 265 0.517 0.731 8.9E-16 0.100 None 0 0
Entrez Id: 335
Gene Symbol: APOA1
APOA1
P02647 apolipoprotein A1 416 0.429 0.885 5.5E-04 0.080 None 1.000 8 0 1986 2008
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
P29474 nitric oxide synthase 3 706 0.378 0.885 6.7E-07 0.050 None 1.000 5 1 2005 2017
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.050 None 0.800 5 1 1997 2008
Entrez Id: 4018
Gene Symbol: LPA
LPA
P08519 lipoprotein(a) Enzyme 340 0.444 0.769 6.6E-89 0.050 None 1.000 5 0 1994 2019
Entrez Id: 790
Gene Symbol: CAD
CAD
P27708 carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase Enzyme 249 0.482 0.846 1.00 0.050 None 0.800 5 0 2009 2019
Entrez Id: 4023
Gene Symbol: LPL
LPL
P06858 lipoprotein lipase Enzyme 290 0.474 0.808 1.3E-09 0.040 None 1.000 4 0 1990 2006
Entrez Id: 1071
Gene Symbol: CETP
CETP
P11597 cholesteryl ester transfer protein 188 0.512 0.731 1.2E-23 0.040 None 1.000 4 1 2005 2016
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
P13500 C-C motif chemokine ligand 2 Signaling 1157 0.321 0.962 0.61 0.030 None 1.000 3 1 2008 2015
Entrez Id: 7057
Gene Symbol: THBS1
THBS1
P07996 thrombospondin 1 480 0.407 0.885 1.00 0.030 None 1.000 3 1 2002 2004
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.030 None 1.000 3 1 2007 2017
Entrez Id: 6401
Gene Symbol: SELE
SELE
P16581 selectin E 327 0.447 0.808 7.9E-10 0.030 None 1.000 3 2 2000 2003
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
Q16552 interleukin 17A 1074 0.324 0.923 4.3E-02 0.020 None 1.000 2 0 2015 2015
Entrez Id: 368
Gene Symbol: ABCC6
ABCC6
O95255 ATP binding cassette subfamily C member 6 Transporter 181 0.540 0.654 5.6E-35 0.020 None 0.500 2 1 2002 2005