Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
P01137 transforming growth factor beta 1 Signaling 9 0.287 0.962 3.7E-02 0.200 None 0.833 3 5 1996 2018
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 18 0.337 0.885 3.2E-10 0.200 None 0.900 1 1 1991 2020
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 38 0.338 0.962 1.9E-03 0.200 None 0.980 3 1 1983 2019
Entrez Id: 2335
Gene Symbol: FN1
FN1
P02751 fibronectin 1 Signaling 9 0.365 0.962 1.4E-03 0.180 None 1.000 2 2 2006 2018
Entrez Id: 183
Gene Symbol: AGT
AGT
P01019 angiotensinogen Enzyme modulator 6 0.367 0.923 5.0E-08 0.200 None 0.933 1 1 1995 2019
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
P29474 nitric oxide synthase 3 12 0.378 0.885 6.7E-07 0.500 None 0.918 4 1 1996 2020
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
P05305 endothelin 1 Signaling 12 0.380 0.846 0.46 0.200 None 0.941 1 1 1999 2019
Entrez Id: 5340
Gene Symbol: PLG
PLG
P00747 plasminogen Enzyme 5 0.389 0.923 1.0E-02 0.200 None 1.000 1 1 1996 2019
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
P84022 SMAD family member 3 Transcription factor 53 0.415 0.923 0.80 0.130 None 1.000 3 3 2014 2018
Entrez Id: 1030
Gene Symbol: CDKN2B
CDKN2B
P42772 cyclin dependent kinase inhibitor 2B 5 0.417 0.769 7.3E-03 0.500 None 1.000 1 1 2008 2019
Entrez Id: 2321
Gene Symbol: FLT1
FLT1
P17948 fms related receptor tyrosine kinase 1 Kinase 3 0.419 0.846 1.00 0.150 None 0.875 2 3 2011 2019
Entrez Id: 1080
Gene Symbol: CFTR
CFTR
P13569 CF transmembrane conductance regulator Ion channel 9 0.424 0.885 2.2E-58 0.110 None 1.000 1 2 2002 2018
Entrez Id: 5175
Gene Symbol: PECAM1
PECAM1
P16284 platelet and endothelial cell adhesion molecule 1 Cell adhesion 3 0.426 0.846 0.490 None 1.000 1 1 2003 2018
Entrez Id: 28
Gene Symbol: ABO
ABO
P16442 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Enzyme 61 0.427 0.885 0.500 None 0.900 3 2 2010 2019
Entrez Id: 4018
Gene Symbol: LPA
LPA
P08519 lipoprotein(a) Enzyme 17 0.444 0.769 6.6E-89 0.500 None 0.958 7 8 1988 2019
Entrez Id: 4015
Gene Symbol: LOX
LOX
P28300 lysyl oxidase 1 0.447 0.846 0.99 0.110 None 1.000 1 1 2011 2017
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
P01130 low density lipoprotein receptor 7 0.449 0.885 9.8E-24 0.500 None 0.989 2 2 1986 2020
Entrez Id: 6597
Gene Symbol: SMARCA4
SMARCA4
P51532 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 Epigenetic regulator 11 0.450 0.885 1.00 0.140 None 0.875 3 3 2010 2018
Entrez Id: 7010
Gene Symbol: TEK
TEK
Q02763 TEK receptor tyrosine kinase Kinase 3 0.462 0.692 1.00 0.110 None 1.000 1 1 2007 2018
Entrez Id: 19
Gene Symbol: ABCA1
ABCA1
O95477 ATP binding cassette subfamily A member 1 Transporter 19 0.467 0.846 1.5E-13 0.200 None 0.982 1 1 2000 2019
Entrez Id: 3570
Gene Symbol: IL6R
IL6R
P08887 interleukin 6 receptor Signaling 32 0.471 0.846 3.2E-05 0.200 None 1.000 3 3 2009 2018
Entrez Id: 9839
Gene Symbol: ZEB2
ZEB2
O60315 zinc finger E-box binding homeobox 2 Transcription factor 9 0.471 0.808 1.00 0.100 None 1.000 1 1 2018 2018
Entrez Id: 4023
Gene Symbol: LPL
LPL
P06858 lipoprotein lipase Enzyme 14 0.474 0.808 1.3E-09 0.200 None 0.918 1 4 1993 2020
Entrez Id: 6927
Gene Symbol: HNF1A
HNF1A
P20823 HNF1 homeobox A Nucleic acid binding 20 0.478 0.846 0.96 0.180 None 1.000 4 2 1998 2018
Entrez Id: 6311
Gene Symbol: ATXN2
ATXN2
Q99700 ataxin 2 Nucleic acid binding 100 0.482 0.808 0.85 0.100 None 1.000 4 4 2013 2018