Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3 		Q96P20 NLR family pyrin domain containing 3 805 0.361 0.962 8.1E-04 0.500 None 0.989 91 10 2001 2020
Entrez Id: 4311
Gene Symbol: MME
MME 		P08473 membrane metalloendopeptidase Enzyme 470 0.407 0.808 1.5E-18 0.300 None 1.000 1 0 2003 2003
Entrez Id: 5336
Gene Symbol: PLCG2
PLCG2 		P16885 phospholipase C gamma 2 Enzyme 82 0.588 0.808 1.00 0.300 None 0 0
Entrez Id: 58484
Gene Symbol: NLRC4
NLRC4 		Q9NPP4 NLR family CARD domain containing 4 145 0.556 0.769 9.9E-12 0.300 None 0 0
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.100 None 0.966 58 0 2006 2020
Entrez Id: 3552
Gene Symbol: IL1A
IL1A 		P01583 interleukin 1 alpha 1002 0.333 0.962 1.6E-04 0.100 None 0.931 29 0 2006 2020
Entrez Id: 4210
Gene Symbol: MEFV
MEFV 		O15553 MEFV innate immuity regulator, pyrin 410 0.440 0.885 1.0E-14 0.090 None 1.000 9 0 2004 2020
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.080 None 1.000 8 0 2004 2019
Entrez Id: 834
Gene Symbol: CASP1
CASP1 		P29466 caspase 1 Enzyme 444 0.413 0.885 3.5E-05 0.070 None 1.000 7 1 2009 2015
Entrez Id: 3606
Gene Symbol: IL18
IL18 		Q14116 interleukin 18 750 0.365 0.923 3.1E-02 0.050 None 1.000 5 0 2010 2018
Entrez Id: 1822
Gene Symbol: ATN1
ATN1 		P54259 atrophin 1 499 0.409 0.885 1.00 0.040 None 1.000 4 0 2012 2020
Entrez Id: 828
Gene Symbol: CAPS
CAPS 		Q13938 calcyphosine 50 0.638 0.731 1.7E-05 0.030 None 1.000 3 0 2014 2018
Entrez Id: 10603
Gene Symbol: SH2B2
SH2B2 		O14492 SH2B adaptor protein 2 59 0.623 0.731 1.5E-05 0.030 None 1.000 3 0 2006 2017
Entrez Id: 3569
Gene Symbol: IL6
IL6 		P05231 interleukin 6 2367 0.248 0.962 0.32 0.030 None 0.667 3 0 2011 2018
Entrez Id: 354
Gene Symbol: KLK3
KLK3 		P07288 kallikrein related peptidase 3 Enzyme 358 0.443 0.885 4.4E-06 0.030 None 1.000 3 0 2006 2017
Entrez Id: 4615
Gene Symbol: MYD88
MYD88 		Q99836 MYD88 innate immune signal transduction adaptor Enzyme modulator 480 0.414 0.923 0.12 0.020 None 1.000 2 1 2010 2019
Entrez Id: 4598
Gene Symbol: MVK
MVK 		Q03426 mevalonate kinase Kinase 139 0.576 0.731 0.17 0.020 None 1.000 2 0 2007 2019
Entrez Id: 3586
Gene Symbol: IL10
IL10 		P22301 interleukin 10 1679 0.281 0.923 5.9E-03 0.010 None 1.000 1 0 2014 2014
Entrez Id: 6288
Gene Symbol: SAA1
SAA1 		P0DJI8 serum amyloid A1 Transporter 188 0.513 0.808 1.5E-02 0.010 None 1.000 1 0 2008 2008
Entrez Id: 6289
Gene Symbol: SAA2
SAA2 		P0DJI9 serum amyloid A2 Transporter 103 0.568 0.731 2.7E-06 0.010 None 1.000 1 0 2008 2008
Entrez Id: 64127
Gene Symbol: NOD2
NOD2 		Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 434 0.423 0.923 2.0E-30 0.010 None 1.000 1 0 2009 2009
Entrez Id: 7099
Gene Symbol: TLR4
TLR4 		O00206 toll like receptor 4 1174 0.321 0.962 4.6E-09 0.010 None 1.000 1 0 2018 2018
Entrez Id: 27445
Gene Symbol: PCLO
PCLO 		Q9Y6V0 piccolo presynaptic cytomatrix protein 59 0.656 0.577 1.00 0.010 None 1.000 1 0 2009 2009
Entrez Id: 7132
Gene Symbol: TNFRSF1A
TNFRSF1A 		P19438 TNF receptor superfamily member 1A 487 0.409 0.923 0.99 0.010 None 1.000 1 0 2019 2019
Entrez Id: 22900
Gene Symbol: CARD8
CARD8 		Q9Y2G2 caspase recruitment domain family member 8 78 0.590 0.731 1.8E-06 0.010 None 1.000 1 0 2014 2014