Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.300 None 1.000 1 0 2017 2017
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.300 None 1.000 1 0 2017 2017
Entrez Id: 4609
Gene Symbol: MYC
MYC
P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 821 0.344 0.923 1.00 0.300 None 1.000 1 0 2000 2000
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
O60603 toll like receptor 2 749 0.361 0.923 1.0E-06 0.300 None 1.000 1 0 2017 2017
Entrez Id: 2146
Gene Symbol: EZH2
EZH2
Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 653 0.376 0.885 1.00 0.300 None 1.000 1 0 2010 2010
Entrez Id: 2056
Gene Symbol: EPO
EPO
P01588 erythropoietin 646 0.381 0.885 1.1E-02 0.300 None 1.000 2 0 2003 2005
Entrez Id: 1030
Gene Symbol: CDKN2B
CDKN2B
P42772 cyclin dependent kinase inhibitor 2B 440 0.417 0.769 7.3E-03 0.300 None 1.000 1 0 2007 2007
Entrez Id: 861
Gene Symbol: RUNX1
RUNX1
Q01196 RUNX family transcription factor 1 Transcription factor 412 0.425 0.808 0.65 0.300 None 1.000 1 0 2017 2017
Entrez Id: 1387
Gene Symbol: CREBBP
CREBBP
Q92793 CREB binding protein 438 0.428 0.808 1.00 0.200 None 1.000 2 0 2000 2012
Entrez Id: 1958
Gene Symbol: EGR1
EGR1
P18146 early growth response 1 Nucleic acid binding 378 0.433 0.923 0.35 0.200 None 1.000 8 0 2004 2009
Entrez Id: 3077
Gene Symbol: HFE
HFE
Q30201 homeostatic iron regulator 415 0.436 0.846 2.6E-08 0.300 None 1.000 1 0 2006 2006
Entrez Id: 648
Gene Symbol: BMI1
BMI1
P35226 BMI1 proto-oncogene, polycomb ring finger 309 0.448 0.808 0.94 0.300 None 1.000 1 0 2014 2014
Entrez Id: 546
Gene Symbol: ATRX
ATRX
P46100 ATRX chromatin remodeler 412 0.452 0.808 1.00 0.300 None 1.000 1 0 2009 2009
Entrez Id: 8314
Gene Symbol: BAP1
BAP1
Q92560 BRCA1 associated protein 1 Enzyme 299 0.454 0.731 0.99 0.200 None 0 0
Entrez Id: 5428
Gene Symbol: POLG
POLG
P54098 DNA polymerase gamma, catalytic subunit Enzyme 462 0.457 0.846 2.1E-09 0.200 None 1.000 1 0 2009 2009
Entrez Id: 54790
Gene Symbol: TET2
TET2
Q6N021 tet methylcytosine dioxygenase 2 362 0.458 0.808 4.3E-54 0.300 None 1.000 2 0 2009 2017
Entrez Id: 3065
Gene Symbol: HDAC1
HDAC1
Q13547 histone deacetylase 1 Epigenetic regulator 277 0.460 0.846 0.61 0.300 None 1.000 1 0 2017 2017
Entrez Id: 4869
Gene Symbol: NPM1
NPM1
P06748 nucleophosmin 1 Chaperone 283 0.464 0.846 1.00 0.200 None 1.000 1 0 2005 2005
Entrez Id: 1612
Gene Symbol: DAPK1
DAPK1
P53355 death associated protein kinase 1 Kinase 249 0.472 0.808 1.00 0.300 None 1.000 1 0 2010 2010
Entrez Id: 8877
Gene Symbol: SPHK1
SPHK1
Q9NYA1 sphingosine kinase 1 Kinase 236 0.480 0.808 3.0E-07 0.300 None 1.000 1 0 2008 2008
Entrez Id: 171023
Gene Symbol: ASXL1
ASXL1
Q8IXJ9 ASXL transcriptional regulator 1 296 0.482 0.808 1.3E-14 0.500 None 1.000 2 0 2014 2017
Entrez Id: 2623
Gene Symbol: GATA1
GATA1
P15976 GATA binding protein 1 264 0.483 0.808 0.95 0.500 None 1.000 2 0 1998 2017
Entrez Id: 8837
Gene Symbol: CFLAR
CFLAR
O15519 CASP8 and FADD like apoptosis regulator Enzyme 215 0.485 0.846 1.00 0.300 None 1.000 1 0 2005 2005
Entrez Id: 2624
Gene Symbol: GATA2
GATA2
P23769 GATA binding protein 2 229 0.496 0.654 0.98 0.300 None 1.000 3 0 2011 2017
Entrez Id: 10533
Gene Symbol: ATG7
ATG7
O95352 autophagy related 7 Enzyme 179 0.505 0.769 7.4E-12 0.200 None 0 0