Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.200 None 1.000 2 0 2008 2014
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
P05019 insulin like growth factor 1 1206 0.318 0.885 0.27 0.200 None 1.000 1 0 2014 2014
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1193 0.320 0.923 1.00 0.200 None 1.000 1 0 2008 2008
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
O00206 toll like receptor 4 1174 0.321 0.962 4.6E-09 0.200 None 1.000 2 0 2013 2014
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
P13500 C-C motif chemokine ligand 2 Signaling 1157 0.321 0.962 0.61 0.200 None 1.000 1 0 2015 2015
Entrez Id: 60
Gene Symbol: ACTB
ACTB
P60709 actin beta Cellular structure 1110 0.325 0.923 0.99 0.200 None 1.000 1 0 2014 2014
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.200 None 1.000 1 0 2011 2011
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
P08183 ATP binding cassette subfamily B member 1 Transporter 933 0.344 0.885 1.3E-05 0.200 None 1.000 1 0 2012 2012
Entrez Id: 3952
Gene Symbol: LEP
LEP
P41159 leptin 931 0.349 0.846 0.46 0.200 None 1.000 2 0 2011 2015
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
Q16236 nuclear factor, erythroid 2 like 2 Enzyme 823 0.357 0.885 3.6E-03 0.200 None 1.000 1 0 2013 2013
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3
Q96P20 NLR family pyrin domain containing 3 805 0.361 0.962 8.1E-04 0.200 None 1.000 2 0 2017 2017
Entrez Id: 3606
Gene Symbol: IL18
IL18
Q14116 interleukin 18 750 0.365 0.923 3.1E-02 0.200 None 1.000 1 0 2013 2013
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
Q15848 adiponectin, C1Q and collagen domain containing 679 0.376 0.885 4.6E-09 0.200 None 1.000 2 0 2011 2011
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
Q96EB6 sirtuin 1 Epigenetic regulator 675 0.378 0.885 8.7E-02 0.200 None 1.000 1 0 2007 2007
Entrez Id: 2146
Gene Symbol: EZH2
EZH2
Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 653 0.376 0.885 1.00 0.200 None 1.000 1 0 2013 2013
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
O60674 Janus kinase 2 Kinase 644 0.385 0.885 0.65 0.200 None 1.000 1 0 2008 2008
Entrez Id: 3480
Gene Symbol: IGF1R
IGF1R
P08069 insulin like growth factor 1 receptor Kinase 556 0.399 0.885 0.97 0.200 None 1.000 1 0 2014 2014
Entrez Id: 5599
Gene Symbol: MAPK8
MAPK8
P45983 mitogen-activated protein kinase 8 Kinase 520 0.397 0.885 1.00 0.200 None 1.000 1 0 2014 2014
Entrez Id: 6352
Gene Symbol: CCL5
CCL5
P13501 C-C motif chemokine ligand 5 Signaling 514 0.403 0.885 1.8E-03 0.200 None 1.000 1 0 2017 2017
Entrez Id: 1277
Gene Symbol: COL1A1
COL1A1
P02452 collagen type I alpha 1 chain 487 0.430 0.808 1.00 0.200 None 1.000 1 0 2007 2007
Entrez Id: 3240
Gene Symbol: HP
HP
P00738 haptoglobin Enzyme 464 0.412 0.885 1.7E-05 0.200 None 1.000 1 0 2011 2011
Entrez Id: 3643
Gene Symbol: INSR
INSR
P06213 insulin receptor Kinase 452 0.432 0.846 3.6E-05 0.200 None 1.000 2 0 2017 2017
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
P48357 leptin receptor Signaling 416 0.433 0.808 0.99 0.200 None 1.000 1 0 2011 2011
Entrez Id: 2539
Gene Symbol: G6PD
G6PD
P11413 glucose-6-phosphate dehydrogenase Enzyme 410 0.424 0.846 0.97 0.200 None 1.000 1 0 2010 2010
Entrez Id: 2308
Gene Symbol: FOXO1
FOXO1
Q12778 forkhead box O1 380 0.433 0.846 1.00 0.200 None 1.000 1 0 2018 2018