Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
P51587 BRCA2, DNA repair associated nucleic acid binding 358 0.426 0.793 5.5E-24 0.400 0.923 13 1 2002 2018
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Q86YC2 partner and localizer of BRCA2 122 0.569 0.552 7.3E-20 0.390 0.889 9 0 2009 2016
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 891 0.321 0.828 0.38 0.390 1.000 9 0 1997 2016
Entrez Id: 23022
Gene Symbol: PALLD
PALLD
Q8WX93 palladin, cytoskeletal associated protein transmembrane receptor regulatory/adaptor protein 48 0.652 0.379 6.4E-06 0.330 1.000 3 0 2007 2009
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
P38398 BRCA1, DNA repair associated ligase 411 0.410 0.862 1.8E-28 0.320 1.000 2 0 2009 2016
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
Q13485 SMAD family member 4 transcription factor 426 0.430 0.759 1.00 0.310 1.000 1 0 1997 1997
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.300 0 0
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase enzyme modulator 886 0.350 0.724 9.0E-04 0.300 0 0
Entrez Id: 472
Gene Symbol: ATM
ATM
Q13315 ATM serine/threonine kinase kinase; nucleic acid binding; transferase 486 0.401 0.862 6.0E-46 0.040 1.000 4 0 2013 2016
Entrez Id: 27143
Gene Symbol: PALD1
PALD1
Q9ULE6 phosphatase domain containing, paladin 1 23 0.707 0.207 9.1E-14 0.030 1.000 3 0 2007 2009
Entrez Id: 1017
Gene Symbol: CDK2
CDK2
P24941 cyclin dependent kinase 2 kinase; transferase 195 0.478 0.690 0.89 0.020 1.000 2 0 1997 2014
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 enzyme modulator 589 0.365 0.828 0.90 0.010 1.000 1 0 2013 2013
Entrez Id: 6794
Gene Symbol: STK11
STK11
Q15831 serine/threonine kinase 11 231 0.467 0.655 0.99 0.010 1.000 1 0 2004 2004
Entrez Id: 6690
Gene Symbol: SPINK1
SPINK1
P00995 serine peptidase inhibitor, Kazal type 1 125 0.536 0.621 0.33 0.010 1.000 1 1 2004 2004
Entrez Id: 6041
Gene Symbol: RNASEL
RNASEL
Q05823 ribonuclease L 55 0.607 0.552 2.1E-10 0.010 1.000 1 2 2006 2006
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
P43246 mutS homolog 2 nucleic acid binding 320 0.437 0.690 0.91 0.010 1.000 1 0 2013 2013
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
P40692 mutL homolog 1 nucleic acid binding 356 0.424 0.759 5.1E-05 0.010 1.000 1 0 2013 2013
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
P38936 cyclin dependent kinase inhibitor 1A 369 0.415 0.724 2.1E-03 0.010 1.000 1 0 1997 1997
Entrez Id: 1080
Gene Symbol: CFTR
CFTR
P13569 cystic fibrosis transmembrane conductance regulator transporter 307 0.453 0.793 1.1E-57 0.010 1.000 1 0 2004 2004
Entrez Id: 2189
Gene Symbol: FANCG
FANCG
O15287 FA complementation group G 60 0.648 0.483 2.1E-13 0.010 1.000 1 0 2004 2004
Entrez Id: 2176
Gene Symbol: FANCC
FANCC
Q00597 FA complementation group C 120 0.569 0.655 2.6E-13 0.010 1.000 1 0 2004 2004