Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.400 None 1.000 35 0 1995 2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.400 None 0.963 27 0 1995 2019
Entrez Id: 3827
Gene Symbol: KNG1
KNG1
P01042 kininogen 1 Enzyme modulator 279 0.481 0.885 3.2E-10 0.300 None 1.000 17 0 1988 2011
Entrez Id: 7442
Gene Symbol: TRPV1
TRPV1
Q8NER1 transient receptor potential cation channel subfamily V member 1 Ion channel 404 0.446 0.885 1.0E-16 0.400 None 1.000 16 0 2002 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.400 None 1.000 13 0 1995 2019
Entrez Id: 6863
Gene Symbol: TAC1
TAC1
P20366 tachykinin precursor 1 478 0.424 0.923 0.75 0.330 None 1.000 12 0 1996 2018
Entrez Id: 627
Gene Symbol: BDNF
BDNF
P23560 brain derived neurotrophic factor Signaling 992 0.345 0.923 0.66 0.100 None 1.000 11 2 2017 2019
Entrez Id: 8989
Gene Symbol: TRPA1
TRPA1
O75762 transient receptor potential cation channel subfamily A member 1 Ion channel 160 0.546 0.846 7.2E-35 0.370 None 1.000 10 0 2007 2020
Entrez Id: 4803
Gene Symbol: NGF
NGF
P01138 nerve growth factor Signaling 616 0.391 0.885 0.82 0.390 None 1.000 10 0 2010 2019
Entrez Id: 59341
Gene Symbol: TRPV4
TRPV4
Q9HBA0 transient receptor potential cation channel subfamily V member 4 Ion channel 422 0.457 0.808 2.2E-16 0.380 None 1.000 9 0 2007 2019
Entrez Id: 3586
Gene Symbol: IL10
IL10
P22301 interleukin 10 1679 0.281 0.923 5.9E-03 0.360 None 0.875 8 0 1995 2018
Entrez Id: 2670
Gene Symbol: GFAP
GFAP
P14136 glial fibrillary acidic protein 447 0.421 0.885 1.5E-06 0.370 None 1.000 8 0 2016 2019
Entrez Id: 2904
Gene Symbol: GRIN2B
GRIN2B
Q13224 glutamate ionotropic receptor NMDA type subunit 2B Ion channel 249 0.510 0.692 1.00 0.360 None 1.000 7 0 2009 2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1193 0.320 0.923 1.00 0.070 None 1.000 7 0 2017 2019
Entrez Id: 3700
Gene Symbol: ITIH4
ITIH4
Q14624 inter-alpha-trypsin inhibitor heavy chain 4 Enzyme modulator 129 0.559 0.769 6.4E-13 0.070 None 1.000 7 0 2015 2018
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
P18510 interleukin 1 receptor antagonist 701 0.373 0.923 3.1E-02 0.320 None 1.000 6 0 1996 2019
Entrez Id: 199
Gene Symbol: AIF1
AIF1
P55008 allograft inflammatory factor 1 Calcium-binding protein 166 0.521 0.808 1.9E-06 0.350 None 1.000 6 0 2016 2020
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1
P09429 high mobility group box 1 Nucleic acid binding 724 0.368 0.923 0.82 0.340 None 1.000 5 0 2016 2018
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.330 None 1.000 5 0 2007 2019
Entrez Id: 5579
Gene Symbol: PRKCB
PRKCB
P05771 protein kinase C beta Kinase 317 0.453 0.885 1.00 0.050 None 1.000 5 0 2017 2019
Entrez Id: 6387
Gene Symbol: CXCL12
CXCL12
P48061 C-X-C motif chemokine ligand 12 626 0.379 0.846 0.12 0.050 None 1.000 5 0 2017 2019
Entrez Id: 5578
Gene Symbol: PRKCA
PRKCA
P17252 protein kinase C alpha Kinase 368 0.440 0.846 0.37 0.050 None 1.000 5 0 2017 2019
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
P13500 C-C motif chemokine ligand 2 Signaling 1157 0.321 0.962 0.61 0.340 None 1.000 5 0 2007 2019
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
P28482 mitogen-activated protein kinase 1 Kinase 1059 0.330 0.923 1.00 0.330 None 1.000 5 0 2003 2019
Entrez Id: 112476
Gene Symbol: PRRT2
PRRT2
Q7Z6L0 proline rich transmembrane protein 2 353 0.448 0.808 0.58 0.050 None 1.000 5 0 2017 2019