Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		P04626 erb-b2 receptor tyrosine kinase 2 Kinase 942 0.328 0.923 6.0E-03 0.100 None 0.967 181 2 1989 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2245 0.236 0.962 0.53 0.100 None 0.939 180 6 1991 2020
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 1308 0.295 0.885 0.37 0.100 None 0.948 135 5 1988 2020
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 888 0.319 0.846 1.00 0.100 None 0.944 125 5 2003 2020
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 805 0.320 0.923 7.9E-04 0.100 None 0.945 91 3 1991 2020
Entrez Id: 4830
Gene Symbol: NME1
NME1 		P15531 NME/NM23 nucleoside diphosphate kinase 1 Kinase 317 0.443 0.808 3.2E-03 0.100 None 0.928 83 0 1989 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 1737 0.266 0.923 2.4E-05 0.100 None 0.975 80 2 1994 2019
Entrez Id: 354
Gene Symbol: KLK3
KLK3 		P07288 kallikrein related peptidase 3 Enzyme 350 0.443 0.885 4.4E-06 0.100 None 0.986 72 0 1994 2020
Entrez Id: 2346
Gene Symbol: FOLH1
FOLH1 		Q04609 folate hydrolase 1 Enzyme 304 0.453 0.885 6.2E-09 0.100 None 0.985 68 0 1999 2020
Entrez Id: 960
Gene Symbol: CD44
CD44 		P16070 CD44 molecule (Indian blood group) 664 0.363 0.962 2.4E-07 0.100 None 0.985 68 0 1993 2019
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		P03372 estrogen receptor 1 Nuclear receptor 972 0.324 0.962 1.00 0.100 None 0.984 64 0 1992 2020
Entrez Id: 7852
Gene Symbol: CXCR4
CXCR4 		P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 681 0.362 0.923 1.8E-02 0.100 None 1.000 63 0 2003 2020
Entrez Id: 29126
Gene Symbol: CD274
CD274 		Q9NZQ7 CD274 molecule Receptor 990 0.324 0.923 1.9E-02 0.100 None 0.951 61 0 2014 2019
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1 		Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 1029 0.322 0.923 4.5E-04 0.100 None 0.981 54 0 2017 2020
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		P35222 catenin beta 1 1156 0.303 0.885 1.00 0.100 None 0.940 50 0 2001 2020
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		P14780 matrix metallopeptidase 9 Enzyme 1160 0.305 0.923 1.9E-17 0.100 None 0.979 48 1 1996 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1277 0.292 0.923 1.00 0.100 None 0.957 47 0 2003 2019
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1214 0.300 0.885 0.39 0.100 None 0.957 46 0 1993 2019
Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5 		P06731 CEA cell adhesion molecule 5 423 0.420 0.846 4.2E-10 0.100 None 0.909 44 0 1992 2019
Entrez Id: 367
Gene Symbol: AR
AR 		P10275 androgen receptor Nuclear receptor 762 0.351 0.846 0.99 0.100 None 1.000 40 2 1997 2019
Entrez Id: 3732
Gene Symbol: CD82
CD82 		P27701 CD82 molecule 157 0.507 0.731 1.3E-08 0.100 None 0.975 40 0 1996 2019
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A 		Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 953 0.327 0.923 0.98 0.100 None 1.000 39 1 2004 2020
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 983 0.305 0.923 0.26 0.100 None 0.974 39 0 1998 2019
Entrez Id: 4313
Gene Symbol: MMP2
MMP2 		P08253 matrix metallopeptidase 2 Enzyme 826 0.333 0.923 0.84 0.100 None 1.000 34 0 2001 2020
Entrez Id: 10855
Gene Symbol: HPSE
HPSE 		Q9Y251 heparanase Enzyme 378 0.425 0.808 2.3E-14 0.100 None 1.000 32 0 1999 2020