Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
P05305 endothelin 1 Signaling 679 0.380 0.846 0.46 0.100 None 1.000 14 0 2010 2019
Entrez Id: 857
Gene Symbol: CAV1
CAV1
Q03135 caveolin 1 Enzyme modulator 633 0.388 0.885 8.3E-03 0.500 moderate 0.909 11 0 2012 2019
Entrez Id: 5053
Gene Symbol: PAH
PAH
P00439 phenylalanine hydroxylase 219 0.516 0.769 6.4E-23 0.090 None 1.000 9 0 2012 2019
Entrez Id: 8654
Gene Symbol: PDE5A
PDE5A
O76074 phosphodiesterase 5A 187 0.513 0.731 1.1E-04 0.090 None 1.000 9 0 2007 2020
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 1044 0.327 0.923 0.98 0.080 None 1.000 8 0 2008 2019
Entrez Id: 3777
Gene Symbol: KCNK3
KCNK3
O14649 potassium two pore domain channel subfamily K member 3 Ion channel 93 0.584 0.654 0.90 0.460 strong 0.857 7 0 2016 2019
Entrez Id: 6590
Gene Symbol: SLPI
SLPI
P03973 secretory leukocyte peptidase inhibitor Enzyme modulator 310 0.449 0.846 9.0E-04 0.070 None 0.857 7 0 2003 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.060 None 1.000 6 0 2007 2020
Entrez Id: 3958
Gene Symbol: LGALS3
LGALS3
P17931 galectin 3 Signaling 557 0.392 0.846 2.3E-05 0.050 None 1.000 5 0 2017 2019
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 877 0.358 0.885 2.9E-02 0.150 None 1.000 5 0 2010 2020
Entrez Id: 440275
Gene Symbol: EIF2AK4
EIF2AK4
Q9P2K8 eukaryotic translation initiation factor 2 alpha kinase 4 89 0.603 0.577 1.2E-15 0.440 strong 1.000 5 0 2015 2019
Entrez Id: 2658
Gene Symbol: GDF2
GDF2
Q9UK05 growth differentiation factor 2 Signaling 152 0.529 0.731 2.5E-03 0.140 None 1.000 4 0 2015 2020
Entrez Id: 8862
Gene Symbol: APLN
APLN
Q9ULZ1 apelin 226 0.497 0.769 0.46 0.040 None 1.000 4 0 2013 2019
Entrez Id: 2305
Gene Symbol: FOXM1
FOXM1
Q08050 forkhead box M1 323 0.441 0.769 7.4E-04 0.040 None 1.000 4 0 2018 2020
Entrez Id: 50507
Gene Symbol: NOX4
NOX4
Q9NPH5 NADPH oxidase 4 Enzyme 260 0.471 0.885 5.8E-20 0.040 None 1.000 4 0 2014 2019
Entrez Id: 1666
Gene Symbol: DECR1
DECR1
Q16698 2,4-dienoyl-CoA reductase 1 Enzyme 399 0.426 0.885 4.5E-14 0.040 None 1.000 4 0 2016 2018
Entrez Id: 1909
Gene Symbol: EDNRA
EDNRA
P25101 endothelin receptor type A G-protein coupled receptor 427 0.426 0.885 0.99 0.040 None 1.000 4 0 2012 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.040 None 1.000 4 0 2017 2019
Entrez Id: 9518
Gene Symbol: GDF15
GDF15
Q99988 growth differentiation factor 15 Signaling 389 0.429 0.808 3.0E-07 0.040 None 1.000 4 0 2011 2020
Entrez Id: 5740
Gene Symbol: PTGIS
PTGIS
Q16647 prostaglandin I2 synthase 70 0.617 0.654 1.2E-09 0.040 None 1.000 4 0 2004 2014
Entrez Id: 3082
Gene Symbol: HGF
HGF
P14210 hepatocyte growth factor Enzyme 671 0.374 0.885 1.00 0.040 None 1.000 4 0 2004 2018
Entrez Id: 187
Gene Symbol: APLNR
APLNR
P35414 apelin receptor G-protein coupled receptor 94 0.588 0.692 0.79 0.040 None 1.000 4 0 2017 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.040 None 1.000 4 0 2015 2019
Entrez Id: 5739
Gene Symbol: PTGIR
PTGIR
P43119 prostaglandin I2 receptor G-protein coupled receptor 27 0.711 0.423 8.9E-04 0.040 None 1.000 4 0 2017 2019
Entrez Id: 4093
Gene Symbol: SMAD9
SMAD9
O15198 SMAD family member 9 Transcription factor 43 0.666 0.308 6.4E-05 0.420 None 0.667 3 0 2013 2015