Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.010 None 1.000 1 0 2014 2014
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.010 None 1.000 1 0 2011 2011
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.010 None 1.000 1 0 2015 2015
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.010 None 1.000 1 0 2019 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.020 None 0.500 2 0 2006 2008
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.010 None 1.000 1 0 2008 2008
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		P35222 catenin beta 1 1368 0.303 0.885 1.00 0.010 None 1.000 1 0 2011 2011
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.010 None 1.000 1 0 2011 2011
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.030 None 1.000 3 0 2007 2008
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.040 None 1.000 4 1 2007 2016
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1 		Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 1034 0.322 0.923 4.5E-04 0.010 None 1.000 1 0 2019 2019
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.020 None 1.000 2 0 2008 2018
Entrez Id: 3952
Gene Symbol: LEP
LEP 		P41159 leptin 931 0.349 0.846 0.46 0.010 None 1.000 1 0 2019 2019
Entrez Id: 4582
Gene Symbol: MUC1
MUC1 		P15941 mucin 1, cell surface associated 594 0.384 0.885 1.9E-02 0.030 None 1.000 3 0 2010 2019
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4 		Q13485 SMAD family member 4 Transcription factor 575 0.401 0.808 1.00 0.010 None 1.000 1 0 2011 2011
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		P43246 mutS homolog 2 Nucleic acid binding 490 0.406 0.808 0.90 0.010 None 1.000 1 0 2009 2009
Entrez Id: 2778
Gene Symbol: GNAS
GNAS 		O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 536 0.420 0.885 0.68 0.050 None 1.000 5 1 2013 2019
Entrez Id: 1080
Gene Symbol: CFTR
CFTR 		P13569 CF transmembrane conductance regulator Ion channel 476 0.424 0.885 2.2E-58 0.010 None 1.000 1 0 2017 2017
Entrez Id: 29072
Gene Symbol: SETD2
SETD2 		Q9BYW2 SET domain containing 2, histone lysine methyltransferase Epigenetic regulator 447 0.424 0.846 1.00 0.010 None 1.000 1 0 2019 2019
Entrez Id: 10631
Gene Symbol: POSTN
POSTN 		Q15063 periostin Signaling 378 0.428 0.885 1.1E-09 0.010 None 1.000 1 0 2008 2008
Entrez Id: 9518
Gene Symbol: GDF15
GDF15 		Q99988 growth differentiation factor 15 Signaling 389 0.429 0.808 3.0E-07 0.010 None 1.000 1 0 2019 2019
Entrez Id: 6935
Gene Symbol: ZEB1
ZEB1 		P37275 zinc finger E-box binding homeobox 1 Transcription factor 310 0.442 0.808 0.97 0.010 None 1.000 1 0 2018 2018
Entrez Id: 6597
Gene Symbol: SMARCA4
SMARCA4 		P51532 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 Epigenetic regulator 347 0.450 0.885 1.00 0.020 None 1.000 2 0 2012 2014
Entrez Id: 361
Gene Symbol: AQP4
AQP4 		P55087 aquaporin 4 Ion channel 311 0.456 0.885 2.3E-03 0.010 None 1.000 1 0 2019 2019
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		P52701 mutS homolog 6 Nucleic acid binding 296 0.462 0.731 3.7E-05 0.010 None 1.000 1 0 2009 2009