Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 143686
Gene Symbol: SESN3
SESN3
P58005 sestrin 3 Enzyme 26 0.705 0.423 0.68 0.010 None < 0.001 1 0 2020 2020
Entrez Id: 4922
Gene Symbol: NTS
NTS
P30990 neurotensin 184 0.517 0.769 3.9E-05 0.010 None < 0.001 1 0 2018 2018
Entrez Id: 9518
Gene Symbol: GDF15
GDF15
Q99988 growth differentiation factor 15 Signaling 389 0.429 0.808 3.0E-07 0.010 None < 0.001 1 0 2018 2018
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 1044 0.327 0.923 0.98 0.030 None 0.667 3 0 2018 2019
Entrez Id: 5919
Gene Symbol: RARRES2
RARRES2
Q99969 retinoic acid receptor responder 2 180 0.519 0.731 2.7E-05 0.030 None 0.667 3 0 2013 2018
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
P05181 cytochrome P450 family 2 subfamily E member 1 306 0.459 0.885 8.1E-09 0.350 None 0.833 6 0 2003 2016
Entrez Id: 80339
Gene Symbol: PNPLA3
PNPLA3
Q9NST1 patatin like phospholipase domain containing 3 Enzyme 132 0.556 0.692 5.7E-08 0.500 None 1.000 22 3 2008 2020
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
Q16236 nuclear factor, erythroid 2 like 2 Enzyme 823 0.357 0.885 3.6E-03 0.400 None 1.000 11 0 2012 2020
Entrez Id: 2551
Gene Symbol: GABPA
GABPA
Q06546 GA binding protein transcription factor subunit alpha Transcription factor 632 0.379 0.885 1.00 0.100 None 1.000 10 0 2012 2020
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.100 None 1.000 10 0 2001 2018
Entrez Id: 2875
Gene Symbol: GPT
GPT
P24298 glutamic--pyruvic transaminase Enzyme 511 0.403 0.923 3.6E-19 0.100 None 1.000 10 0 2007 2019
Entrez Id: 5465
Gene Symbol: PPARA
PPARA
Q07869 peroxisome proliferator activated receptor alpha Nuclear receptor 408 0.432 0.885 3.0E-02 0.390 None 1.000 9 1 2005 2019
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
Q15848 adiponectin, C1Q and collagen domain containing 679 0.376 0.885 4.6E-09 0.380 None 1.000 9 1 2003 2017
Entrez Id: 3077
Gene Symbol: HFE
HFE
Q30201 homeostatic iron regulator 415 0.436 0.846 2.6E-08 0.090 None 1.000 9 2 1999 2010
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3
Q96P20 NLR family pyrin domain containing 3 805 0.361 0.962 8.1E-04 0.070 None 1.000 7 0 2017 2020
Entrez Id: 4217
Gene Symbol: MAP3K5
MAP3K5
Q99683 mitogen-activated protein kinase kinase kinase 5 Kinase 170 0.513 0.808 0.52 0.070 None 1.000 7 0 2018 2020
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
O00206 toll like receptor 4 1174 0.321 0.962 4.6E-09 0.060 None 1.000 6 0 2014 2019
Entrez Id: 4547
Gene Symbol: MTTP
MTTP
P55157 microsomal triglyceride transfer protein Transporter 209 0.505 0.846 1.0E-05 0.060 None 1.000 6 0 2004 2011
Entrez Id: 6524
Gene Symbol: SLC5A2
SLC5A2
P31639 solute carrier family 5 member 2 Transporter 214 0.499 0.769 4.9E-14 0.060 None 1.000 6 0 2018 2020
Entrez Id: 9213
Gene Symbol: XPR1
XPR1
Q9UBH6 xenotropic and polytropic retrovirus receptor 1 Transporter 217 0.488 0.731 1.00 0.050 None 1.000 5 0 2017 2020
Entrez Id: 3875
Gene Symbol: KRT18
KRT18
P05783 keratin 18 151 0.530 0.692 0.73 0.050 None 1.000 5 0 2017 2019
Entrez Id: 26291
Gene Symbol: FGF21
FGF21
Q9NSA1 fibroblast growth factor 21 Signaling 236 0.485 0.769 2.9E-02 0.330 None 1.000 5 0 2010 2019
Entrez Id: 3949
Gene Symbol: LDLR
LDLR
P01130 low density lipoprotein receptor 336 0.449 0.885 9.8E-24 0.320 None 1.000 5 0 2010 2020
Entrez Id: 3952
Gene Symbol: LEP
LEP
P41159 leptin 931 0.349 0.846 0.46 0.340 None 1.000 5 0 2006 2017
Entrez Id: 948
Gene Symbol: CD36
CD36
P16671 CD36 molecule Receptor 351 0.446 0.846 1.1E-60 0.050 None 1.000 5 0 2010 2018