Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.100 None 1.000 42 0 2007 2020
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3
Q96P20 NLR family pyrin domain containing 3 805 0.361 0.962 8.1E-04 0.100 None 1.000 31 1 2002 2020
Entrez Id: 4210
Gene Symbol: MEFV
MEFV
O15553 MEFV innate immuity regulator, pyrin 410 0.440 0.885 1.0E-14 0.100 None 1.000 24 0 2002 2020
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
P01583 interleukin 1 alpha 1002 0.333 0.962 1.6E-04 0.100 None 1.000 23 0 2007 2020
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.100 None 1.000 12 0 2006 2019
Entrez Id: 64127
Gene Symbol: NOD2
NOD2
Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 434 0.423 0.923 2.0E-30 0.070 None 1.000 7 0 2003 2019
Entrez Id: 7132
Gene Symbol: TNFRSF1A
TNFRSF1A
P19438 TNF receptor superfamily member 1A 487 0.409 0.923 0.99 0.070 None 1.000 7 1 2006 2019
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
P18510 interleukin 1 receptor antagonist 701 0.373 0.923 3.1E-02 0.050 None 1.000 5 0 2008 2017
Entrez Id: 9051
Gene Symbol: PSTPIP1
PSTPIP1
O43586 proline-serine-threonine phosphatase interacting protein 1 Cellular structure 54 0.650 0.577 2.5E-06 0.040 None 1.000 4 0 2009 2017
Entrez Id: 340061
Gene Symbol: STING1
STING1
Q86WV6 stimulator of interferon response cGAMP interactor 1 159 0.522 0.769 1.2E-03 0.040 None 1.000 4 2 2016 2019
Entrez Id: 834
Gene Symbol: CASP1
CASP1
P29466 caspase 1 Enzyme 444 0.413 0.885 3.5E-05 0.040 None 1.000 4 0 2011 2017
Entrez Id: 91662
Gene Symbol: NLRP12
NLRP12
P59046 NLR family pyrin domain containing 12 95 0.569 0.846 3.6E-28 0.040 None 1.000 4 0 2011 2019
Entrez Id: 7128
Gene Symbol: TNFAIP3
TNFAIP3
P21580 TNF alpha induced protein 3 Enzyme 212 0.481 0.808 1.00 0.040 None 1.000 4 0 2016 2020
Entrez Id: 58484
Gene Symbol: NLRC4
NLRC4
Q9NPP4 NLR family CARD domain containing 4 145 0.556 0.769 9.9E-12 0.040 None 1.000 4 2 2014 2019
Entrez Id: 1822
Gene Symbol: ATN1
ATN1
P54259 atrophin 1 499 0.409 0.885 1.00 0.030 None 1.000 3 0 2012 2020
Entrez Id: 22861
Gene Symbol: NLRP1
NLRP1
Q9C000 NLR family pyrin domain containing 1 200 0.502 0.769 5.0E-19 0.030 None 1.000 3 0 2007 2018
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1
P19838 nuclear factor kappa B subunit 1 Transcription factor 551 0.396 0.923 1.00 0.030 None 1.000 3 0 2017 2018
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
Q16552 interleukin 17A 1074 0.324 0.923 4.3E-02 0.030 None 1.000 3 0 2017 2019
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
O00206 toll like receptor 4 1174 0.321 0.962 4.6E-09 0.020 None 1.000 2 2 2013 2018
Entrez Id: 3606
Gene Symbol: IL18
IL18
Q14116 interleukin 18 750 0.365 0.923 3.1E-02 0.020 None 1.000 2 0 2009 2019
Entrez Id: 4598
Gene Symbol: MVK
MVK
Q03426 mevalonate kinase Kinase 139 0.576 0.731 0.17 0.020 None 1.000 2 0 2016 2019
Entrez Id: 22900
Gene Symbol: CARD8
CARD8
Q9Y2G2 caspase recruitment domain family member 8 78 0.590 0.731 1.8E-06 0.020 None 1.000 2 0 2009 2017
Entrez Id: 8737
Gene Symbol: RIPK1
RIPK1
Q13546 receptor interacting serine/threonine kinase 1 Kinase 250 0.479 0.769 7.9E-03 0.020 None 1.000 2 0 2020 2020
Entrez Id: 51816
Gene Symbol: ADA2
ADA2
Q9NZK5 adenosine deaminase 2 Enzyme 165 0.545 0.846 8.1E-08 0.020 None 1.000 2 0 2017 2019
Entrez Id: 29108
Gene Symbol: PYCARD
PYCARD
Q9ULZ3 PYD and CARD domain containing Enzyme 294 0.457 0.808 2.0E-04 0.020 None 1.000 2 0 2014 2017