Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2176
Gene Symbol: FANCC
FANCC 		Q00597 FA complementation group C 218 0.507 0.808 2.8E-13 0.200 None 1.000 63 4 1993 2019
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		P38398 BRCA1 DNA repair associated Enzyme 747 0.367 0.923 9.2E-29 0.200 None 1.000 42 4 2001 2020
Entrez Id: 55215
Gene Symbol: FANCI
FANCI 		Q9NVI1 FA complementation group I 147 0.543 0.731 8.9E-37 0.100 None 1.000 27 0 2007 2019
Entrez Id: 79728
Gene Symbol: PALB2
PALB2 		Q86YC2 partner and localizer of BRCA2 260 0.485 0.769 3.0E-19 0.100 None 1.000 23 0 2007 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.100 None 1.000 20 0 1994 2019
Entrez Id: 92822
Gene Symbol: ZNF276
ZNF276 		Q8N554 zinc finger protein 276 Transcription factor 8 0.861 0.192 7.9E-06 0.110 None 1.000 20 27 1997 2018
Entrez Id: 5888
Gene Symbol: RAD51
RAD51 		Q06609 RAD51 recombinase 363 0.447 0.846 2.7E-02 0.100 None 1.000 20 0 2002 2019
Entrez Id: 55120
Gene Symbol: FANCL
FANCL 		Q9NW38 FA complementation group L Enzyme 137 0.551 0.731 5.9E-23 0.100 None 1.000 19 1 2003 2020
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		O43502 RAD51 paralog C 162 0.533 0.692 6.2E-14 0.100 None 1.000 16 1 2010 2019
Entrez Id: 2188
Gene Symbol: FANCF
FANCF 		Q9NPI8 FA complementation group F 153 0.535 0.731 0.46 0.100 None 1.000 16 0 2001 2019
Entrez Id: 84464
Gene Symbol: SLX4
SLX4 		Q8IY92 SLX4 structure-specific endonuclease subunit 123 0.565 0.731 1.6E-22 0.100 None 1.000 12 0 2011 2016
Entrez Id: 472
Gene Symbol: ATM
ATM 		Q13315 ATM serine/threonine kinase Kinase 684 0.374 0.885 5.6E-47 0.100 None 1.000 11 0 2002 2017
Entrez Id: 79594
Gene Symbol: MUL1
MUL1 		Q969V5 mitochondrial E3 ubiquitin protein ligase 1 241 0.473 0.808 1.9E-06 0.100 None 1.000 10 0 2006 2019
Entrez Id: 158506
Gene Symbol: CBLL2
CBLL2 		Q8N7E2 Cbl proto-oncogene like 2 Enzyme 235 0.476 0.808 0.100 None 1.000 10 0 2006 2019
Entrez Id: 5071
Gene Symbol: PRKN
PRKN 		O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 409 0.431 0.846 6.9E-07 0.100 None 1.000 10 0 2006 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.100 None 1.000 10 0 1994 2014
Entrez Id: 947
Gene Symbol: CD34
CD34 		P28906 CD34 molecule 674 0.368 0.808 5.0E-06 0.090 None 1.000 9 0 1994 2018
Entrez Id: 641
Gene Symbol: BLM
BLM 		P54132 BLM RecQ like helicase 158 0.535 0.808 1.5E-15 0.090 None 1.000 9 0 2003 2019
Entrez Id: 2178
Gene Symbol: FANCE
FANCE 		Q9HB96 FA complementation group E 144 0.553 0.808 1.5E-06 0.080 None 1.000 8 0 1997 2017
Entrez Id: 29089
Gene Symbol: UBE2T
UBE2T 		Q9NPD8 ubiquitin conjugating enzyme E2 T 137 0.550 0.731 1.1E-05 0.080 None 1.000 8 0 2011 2019
Entrez Id: 545
Gene Symbol: ATR
ATR 		Q13535 ATR serine/threonine kinase Kinase 321 0.456 0.923 3.5E-09 0.070 None 1.000 7 0 2005 2015
Entrez Id: 1111
Gene Symbol: CHEK1
CHEK1 		O14757 checkpoint kinase 1 Kinase 195 0.492 0.808 3.1E-08 0.070 None 1.000 7 0 2009 2017
Entrez Id: 3458
Gene Symbol: IFNG
IFNG 		P01579 interferon gamma 1519 0.288 0.962 0.47 0.070 None 1.000 7 0 1997 2012
Entrez Id: 2184
Gene Symbol: FAH
FAH 		P16930 fumarylacetoacetate hydrolase 78 0.612 0.538 4.0E-17 0.070 None 1.000 7 0 1997 1999
Entrez Id: 1302
Gene Symbol: COL11A2
COL11A2 		P13942 collagen type XI alpha 2 chain 399 0.435 0.846 0.70 0.060 None 1.000 6 0 2003 2016