Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3 		Q96P20 NLR family pyrin domain containing 3 805 0.361 0.962 8.1E-04 0.400 strong 1.000 18 0 2004 2020
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.100 None 1.000 13 0 2010 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.100 None 1.000 12 0 2004 2019
Entrez Id: 7132
Gene Symbol: TNFRSF1A
TNFRSF1A 		P19438 TNF receptor superfamily member 1A 487 0.409 0.923 0.99 0.380 strong 1.000 9 0 2004 2015
Entrez Id: 3552
Gene Symbol: IL1A
IL1A 		P01583 interleukin 1 alpha 1002 0.333 0.962 1.6E-04 0.090 None 1.000 9 0 2010 2019
Entrez Id: 4598
Gene Symbol: MVK
MVK 		Q03426 mevalonate kinase Kinase 139 0.576 0.731 0.17 0.340 strong 1.000 5 0 2003 2019
Entrez Id: 64127
Gene Symbol: NOD2
NOD2 		Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 434 0.423 0.923 2.0E-30 0.330 strong 1.000 4 0 1985 2019
Entrez Id: 25939
Gene Symbol: SAMHD1
SAMHD1 		Q9Y3Z3 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 169 0.547 0.769 6.5E-13 0.320 strong 1.000 3 0 2010 2018
Entrez Id: 834
Gene Symbol: CASP1
CASP1 		P29466 caspase 1 Enzyme 444 0.413 0.885 3.5E-05 0.030 None 1.000 3 0 2005 2015
Entrez Id: 58484
Gene Symbol: NLRC4
NLRC4 		Q9NPP4 NLR family CARD domain containing 4 145 0.556 0.769 9.9E-12 0.320 strong 1.000 3 0 2017 2020
Entrez Id: 3606
Gene Symbol: IL18
IL18 		Q14116 interleukin 18 750 0.365 0.923 3.1E-02 0.030 None 1.000 3 0 2012 2018
Entrez Id: 22861
Gene Symbol: NLRP1
NLRP1 		Q9C000 NLR family pyrin domain containing 1 200 0.502 0.769 5.0E-19 0.320 moderate 1.000 3 0 2009 2018
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN 		P18510 interleukin 1 receptor antagonist 701 0.373 0.923 3.1E-02 0.310 strong 1.000 2 0 2009 2011
Entrez Id: 3569
Gene Symbol: IL6
IL6 		P05231 interleukin 6 2367 0.248 0.962 0.32 0.020 None 1.000 2 0 2011 2013
Entrez Id: 51752
Gene Symbol: ERAP1
ERAP1 		Q9NZ08 endoplasmic reticulum aminopeptidase 1 Enzyme 156 0.556 0.692 2.1E-26 0.020 None 1.000 2 0 2017 2019
Entrez Id: 55315
Gene Symbol: SLC29A3
SLC29A3 		Q9BZD2 solute carrier family 29 member 3 Transporter 123 0.578 0.769 1.3E-07 0.310 strong 1.000 2 0 2012 2013
Entrez Id: 103
Gene Symbol: ADAR
ADAR 		P55265 adenosine deaminase RNA specific Enzyme 256 0.501 0.808 2.6E-02 0.310 strong 1.000 2 0 2012 2018
Entrez Id: 5696
Gene Symbol: PSMB8
PSMB8 		P28062 proteasome 20S subunit beta 8 165 0.533 0.808 2.2E-02 0.310 strong 1.000 2 0 2011 2012
Entrez Id: 340061
Gene Symbol: STING1
STING1 		Q86WV6 stimulator of interferon response cGAMP interactor 1 159 0.522 0.769 1.2E-03 0.310 strong 1.000 2 0 2014 2019
Entrez Id: 11277
Gene Symbol: TREX1
TREX1 		Q9NSU2 three prime repair exonuclease 1 241 0.517 0.808 0.58 0.310 strong 1.000 2 0 2015 2018
Entrez Id: 64135
Gene Symbol: IFIH1
IFIH1 		Q9BYX4 interferon induced with helicase C domain 1 319 0.471 0.808 7.0E-44 0.300 strong 1.000 1 0 2017 2017
Entrez Id: 9219
Gene Symbol: MTA2
MTA2 		O94776 metastasis associated 1 family member 2 Nucleic acid binding 93 0.579 0.808 0.74 0.010 None 1.000 1 0 2019 2019
Entrez Id: 6288
Gene Symbol: SAA1
SAA1 		P0DJI8 serum amyloid A1 Transporter 188 0.513 0.808 1.5E-02 0.010 None 1.000 1 0 2009 2009
Entrez Id: 6098
Gene Symbol: ROS1
ROS1 		P08922 ROS proto-oncogene 1, receptor tyrosine kinase Kinase 356 0.439 0.885 1.6E-72 0.010 None 1.000 1 0 2011 2011
Entrez Id: 5336
Gene Symbol: PLCG2
PLCG2 		P16885 phospholipase C gamma 2 Enzyme 82 0.588 0.808 1.00 0.300 strong 1.000 1 0 2018 2018