Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.400 None 0.973 110 5 1992 2020
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.400 None 0.954 87 0 1989 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.400 None 1.000 18 0 2008 2020
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1083 0.322 0.885 1.00 0.400 None 1.000 14 0 2013 2020
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.360 None 1.000 6 0 1993 2019
Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3
P21860 erb-b2 receptor tyrosine kinase 3 Kinase 318 0.448 0.808 1.7E-15 0.360 None 1.000 6 0 1993 2019
Entrez Id: 79577
Gene Symbol: CDC73
CDC73
Q6P1J9 cell division cycle 73 144 0.543 0.615 1.00 0.310 None 1.000 1 0 2015 2015
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
P21802 fibroblast growth factor receptor 2 Kinase 731 0.380 0.808 1.00 0.300 None 0 0
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
P11362 fibroblast growth factor receptor 1 Kinase 816 0.362 0.885 1.00 0.300 None 0 0
Entrez Id: 1540
Gene Symbol: CYLD
CYLD
Q9NQC7 CYLD lysine 63 deubiquitinase Enzyme 211 0.498 0.846 1.00 0.300 None 0 0
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.100 None 0.974 39 1 1997 2020
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10
H3 histone pseudogene 10 769 0.350 0.846 0.100 None 1.000 22 0 1997 2020
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 1034 0.322 0.923 4.5E-04 0.100 None 1.000 21 0 2017 2019
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
P09488 glutathione S-transferase mu 1 627 0.380 0.923 2.1E-03 0.100 None 0.952 21 1 1998 2015
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1193 0.320 0.923 1.00 0.100 None 1.000 20 0 2000 2020
Entrez Id: 29126
Gene Symbol: CD274
CD274
Q9NZQ7 CD274 molecule Receptor 1011 0.324 0.923 1.9E-02 0.100 None 0.944 18 0 2017 2020
Entrez Id: 7515
Gene Symbol: XRCC1
XRCC1
P18887 X-ray repair cross complementing 1 410 0.421 0.923 6.3E-09 0.100 None 0.882 17 3 2002 2018
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
P04798 cytochrome P450 family 1 subfamily A member 1 Enzyme 379 0.436 0.846 1.1E-17 0.100 None 1.000 15 1 1998 2015
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.100 None 0.929 14 2 2000 2019
Entrez Id: 960
Gene Symbol: CD44
CD44
P16070 CD44 molecule (Indian blood group) 711 0.363 0.962 2.4E-07 0.100 None 1.000 14 0 2005 2019
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.100 None 0.857 14 1 1994 2016
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1101 0.320 0.885 1.4E-06 0.100 None 1.000 14 0 2013 2020
Entrez Id: 27306
Gene Symbol: HPGDS
HPGDS
O60760 hematopoietic prostaglandin D synthase 570 0.388 0.923 1.8E-06 0.100 None 1.000 14 0 1995 2014
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1119 0.319 0.885 1.00 0.100 None 1.000 14 0 2013 2020
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1
P30711 glutathione S-transferase theta 1 541 0.393 0.923 1.5E-04 0.100 None 0.929 14 0 1998 2015