Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4598
Gene Symbol: MVK
MVK 		Q03426 mevalonate kinase Kinase 139 0.576 0.731 0.17 0.100 None 1.000 13 3 1999 2019
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3 		Q96P20 NLR family pyrin domain containing 3 805 0.361 0.962 8.1E-04 0.100 None 1.000 11 0 2008 2020
Entrez Id: 7132
Gene Symbol: TNFRSF1A
TNFRSF1A 		P19438 TNF receptor superfamily member 1A 487 0.409 0.923 0.99 0.070 None 1.000 7 0 2001 2019
Entrez Id: 4210
Gene Symbol: MEFV
MEFV 		O15553 MEFV innate immuity regulator, pyrin 410 0.440 0.885 1.0E-14 0.070 None 1.000 7 3 2004 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.050 None 1.000 5 0 2001 2010
Entrez Id: 91662
Gene Symbol: NLRP12
NLRP12 		P59046 NLR family pyrin domain containing 12 95 0.569 0.846 3.6E-28 0.040 None 1.000 4 0 2008 2017
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.030 None 1.000 3 0 2007 2019
Entrez Id: 834
Gene Symbol: CASP1
CASP1 		P29466 caspase 1 Enzyme 444 0.413 0.885 3.5E-05 0.020 None 1.000 2 0 2013 2015
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN 		P18510 interleukin 1 receptor antagonist 701 0.373 0.923 3.1E-02 0.010 None 1.000 1 0 2008 2008
Entrez Id: 8824
Gene Symbol: CES2
CES2 		O00748 carboxylesterase 2 Enzyme 87 0.584 0.731 3.6E-16 0.010 None 1.000 1 0 2013 2013
Entrez Id: 8737
Gene Symbol: RIPK1
RIPK1 		Q13546 receptor interacting serine/threonine kinase 1 Kinase 250 0.479 0.769 7.9E-03 0.010 None 1.000 1 0 2020 2020
Entrez Id: 828
Gene Symbol: CAPS
CAPS 		Q13938 calcyphosine 50 0.638 0.731 1.7E-05 0.010 None 1.000 1 0 2018 2018
Entrez Id: 79792
Gene Symbol: GSDMD
GSDMD 		P57764 gasdermin D 50 0.641 0.692 1.1E-13 0.010 None 1.000 1 0 2019 2019
Entrez Id: 3552
Gene Symbol: IL1A
IL1A 		P01583 interleukin 1 alpha 1002 0.333 0.962 1.6E-04 0.010 None 1.000 1 0 2007 2007
Entrez Id: 64127
Gene Symbol: NOD2
NOD2 		Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 434 0.423 0.923 2.0E-30 0.010 None 1.000 1 0 2016 2016
Entrez Id: 9552
Gene Symbol: SPAG7
SPAG7 		O75391 sperm associated antigen 7 Nucleic acid binding 8 0.821 0.346 6.8E-04 0.010 None 1.000 1 0 2014 2014