Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
P00441 superoxide dismutase 1 Enzyme 689 0.379 0.962 0.18 0.050 None 1.000 5 1 2002 2010
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
P37840 synuclein alpha Transporter 449 0.427 0.885 0.88 0.040 None 1.000 4 2 2007 2016
Entrez Id: 120892
Gene Symbol: LRRK2
LRRK2
Q5S007 leucine rich repeat kinase 2 Kinase 231 0.510 0.808 2.6E-30 0.030 None 1.000 3 1 2011 2017
Entrez Id: 23435
Gene Symbol: TARDBP
TARDBP
Q13148 TAR DNA binding protein 245 0.493 0.808 0.99 0.020 None 1.000 2 0 2015 2019
Entrez Id: 1674
Gene Symbol: DES
DES
P17661 desmin 330 0.460 0.846 8.8E-03 0.020 None 1.000 2 0 2016 2017
Entrez Id: 5428
Gene Symbol: POLG
POLG
P54098 DNA polymerase gamma, catalytic subunit Enzyme 462 0.457 0.846 2.1E-09 0.020 None 1.000 2 2 2006 2014
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
Q9BXM7 PTEN induced kinase 1 Kinase 209 0.516 0.769 1.9E-10 0.020 None 1.000 2 0 2007 2011
Entrez Id: 9997
Gene Symbol: SCO2
SCO2
O43819 synthesis of cytochrome C oxidase 2 Enzyme 294 0.479 0.846 7.5E-07 0.020 None 1.000 2 0 2009 2018
Entrez Id: 23410
Gene Symbol: SIRT3
SIRT3
Q9NTG7 sirtuin 3 Epigenetic regulator 227 0.488 0.731 1.6E-04 0.020 None 1.000 2 0 2017 2017
Entrez Id: 400916
Gene Symbol: CHCHD10
CHCHD10
Q8WYQ3 coiled-coil-helix-coiled-coil-helix domain containing 10 112 0.623 0.462 5.4E-06 0.020 None 1.000 2 0 2017 2018
Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A
Q9UBK2 PPARG coactivator 1 alpha Transcription factor 350 0.453 0.885 1.00 0.020 None 1.000 2 0 2014 2018
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
P29474 nitric oxide synthase 3 706 0.378 0.885 6.7E-07 0.010 None 1.000 1 0 2015 2015
Entrez Id: 51164
Gene Symbol: DCTN4
DCTN4
Q9UJW0 dynactin subunit 4 253 0.472 0.846 0.73 0.010 None 1.000 1 0 2019 2019
Entrez Id: 4210
Gene Symbol: MEFV
MEFV
O15553 MEFV innate immuity regulator, pyrin 410 0.440 0.885 1.0E-14 0.010 None < 0.001 1 0 2013 2013
Entrez Id: 5598
Gene Symbol: MAPK7
MAPK7
Q13164 mitogen-activated protein kinase 7 Kinase 127 0.553 0.654 3.1E-03 0.010 None 1.000 1 0 2017 2017
Entrez Id: 55486
Gene Symbol: PARL
PARL
Q9H300 presenilin associated rhomboid like Enzyme 20 0.729 0.308 1.9E-04 0.010 None 1.000 1 0 2010 2010
Entrez Id: 4236
Gene Symbol: MFAP1
MFAP1
P55081 microfibril associated protein 1 Extracellular structure 357 0.431 0.846 0.80 0.010 None 1.000 1 0 2012 2012
Entrez Id: 4301
Gene Symbol: AFDN
AFDN
P55196 afadin, adherens junction formation factor Cellular structure 46 0.650 0.462 1.00 0.010 None 1.000 1 0 2017 2017
Entrez Id: 4485
Gene Symbol: MST1
MST1
P26927 macrophage stimulating 1 Enzyme 281 0.465 0.885 4.8E-19 0.010 None 1.000 1 0 2019 2019
Entrez Id: 5376
Gene Symbol: PMP22
PMP22
Q01453 peripheral myelin protein 22 Cellular structure 341 0.471 0.885 0.91 0.010 None 1.000 1 0 2014 2014
Entrez Id: 4550
Gene Symbol: RNR2
RNR2
Q8IVG9 l-rRNA 76 0.603 0.692 0.010 None 1.000 1 0 2006 2006
Entrez Id: 5339
Gene Symbol: PLEC
PLEC
Q15149 plectin Cellular structure 218 0.523 0.808 8.3E-12 0.010 None 1.000 1 0 2013 2013
Entrez Id: 472
Gene Symbol: ATM
ATM
Q13315 ATM serine/threonine kinase Kinase 684 0.374 0.885 5.6E-47 0.010 None 1.000 1 0 2012 2012
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
Q16236 nuclear factor, erythroid 2 like 2 Enzyme 823 0.357 0.885 3.6E-03 0.010 None 1.000 1 0 2019 2019
Entrez Id: 4854
Gene Symbol: NOTCH3
NOTCH3
Q9UM47 notch receptor 3 418 0.435 0.808 0.41 0.010 None 1.000 1 0 2004 2004