Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3 		Q96P20 NLR family pyrin domain containing 3 702 0.361 0.962 8.1E-04 0.020 None 1.000 2 0 1995 2019
Entrez Id: 1401
Gene Symbol: CRP
CRP 		P02741 C-reactive protein 1410 0.299 0.962 3.7E-03 0.010 None 1.000 1 0 2013 2013
Entrez Id: 2215
Gene Symbol: FCGR3B
FCGR3B 		O75015 Fc fragment of IgG receptor IIIb Cell adhesion 277 0.452 0.962 3.0E-07 0.010 None 1.000 1 0 2010 2010
Entrez Id: 3552
Gene Symbol: IL1A
IL1A 		P01583 interleukin 1 alpha 932 0.333 0.962 1.6E-04 0.010 None 1.000 1 0 2010 2010
Entrez Id: 7099
Gene Symbol: TLR4
TLR4 		O00206 toll like receptor 4 1030 0.321 0.962 4.6E-09 0.010 None 1.000 1 0 2017 2017
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		P23560 brain derived neurotrophic factor Signaling 852 0.345 0.923 0.66 0.100 None 0.984 61 0 1993 2019
Entrez Id: 4609
Gene Symbol: MYC
MYC 		P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 747 0.344 0.923 1.00 0.100 None 1.000 54 0 1985 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 1737 0.266 0.923 2.4E-05 0.100 None 0.980 51 0 2000 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1277 0.292 0.923 1.00 0.100 None 0.952 42 0 2002 2019
Entrez Id: 836
Gene Symbol: CASP3
CASP3 		P42574 caspase 3 Enzyme 722 0.351 0.923 0.10 0.100 None 0.974 38 1 2000 2019
Entrez Id: 841
Gene Symbol: CASP8
CASP8 		Q14790 caspase 8 Enzyme 389 0.404 0.923 3.7E-06 0.100 None 0.974 38 1 2000 2019
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1 		P28482 mitogen-activated protein kinase 1 Kinase 935 0.330 0.923 1.00 0.100 None 1.000 37 0 1997 2019
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A 		Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 953 0.327 0.923 0.98 0.100 None 1.000 27 0 2004 2019
Entrez Id: 4137
Gene Symbol: MAPT
MAPT 		P10636 microtubule associated protein tau 256 0.446 0.923 6.0E-03 0.100 None 1.000 22 2 1998 2019
Entrez Id: 5621
Gene Symbol: PRNP
PRNP 		F7VJQ1 P04156 prion protein 293 0.445 0.923 6.3E-04 0.100 None 1.000 17 3 1999 2017
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 983 0.305 0.923 0.26 0.100 None 1.000 17 0 2001 2019
Entrez Id: 4318
Gene Symbol: MMP9
MMP9 		P14780 matrix metallopeptidase 9 Enzyme 1160 0.305 0.923 1.9E-17 0.100 None 1.000 15 0 1999 2018
Entrez Id: 6774
Gene Symbol: STAT3
STAT3 		P40763 signal transducer and activator of transcription 3 Nucleic acid binding 999 0.320 0.923 1.00 0.100 None 1.000 15 0 1999 2019
Entrez Id: 3308
Gene Symbol: HSPA4
HSPA4 		P34932 heat shock protein family A (Hsp70) member 4 534 0.394 0.923 1.00 0.100 None 1.000 14 0 1999 2019
Entrez Id: 1398
Gene Symbol: CRK
CRK 		P46108 CRK proto-oncogene, adaptor protein 538 0.394 0.923 0.96 0.100 None 1.000 13 0 2000 2019
Entrez Id: 1432
Gene Symbol: MAPK14
MAPK14 		Q16539 mitogen-activated protein kinase 14 Kinase 594 0.379 0.923 0.37 0.100 None 1.000 13 0 2000 2019
Entrez Id: 7965
Gene Symbol: AIMP2
AIMP2 		Q13155 aminoacyl tRNA synthetase complex interacting multifunctional protein 2 529 0.393 0.923 8.0E-03 0.100 None 1.000 13 0 2000 2019
Entrez Id: 9402
Gene Symbol: GRAP2
GRAP2 		O75791 GRB2 related adaptor protein 2 537 0.394 0.923 1.5E-04 0.100 None 1.000 13 0 2000 2019
Entrez Id: 10598
Gene Symbol: AHSA1
AHSA1 		O95433 activator of HSP90 ATPase activity 1 526 0.396 0.923 1.00 0.100 None 1.000 13 0 2000 2019
Entrez Id: 25897
Gene Symbol: RNF19A
RNF19A 		Q9NV58 ring finger protein 19A, RBR E3 ubiquitin protein ligase Enzyme 523 0.397 0.923 2.5E-02 0.100 None 1.000 13 0 2000 2019