Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.010 None 1.000 1 0 2013 2013
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.030 None 0.667 3 0 2000 2012
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.010 None < 0.001 1 0 2001 2001
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.010 None < 0.001 1 0 2000 2000
Entrez Id: 4609
Gene Symbol: MYC
MYC
P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 821 0.344 0.923 1.00 0.010 None 1.000 1 0 2010 2010
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
P46531 notch receptor 1 693 0.369 0.885 1.00 0.010 None 1.000 1 0 2012 2012
Entrez Id: 2688
Gene Symbol: GH1
GH1
P01241 growth hormone 1 Signaling 686 0.373 0.923 3.0E-02 0.010 None 1.000 1 0 2010 2010
Entrez Id: 3342
Gene Symbol: HTC2
HTC2
hypertrichosis 2 (generalized, congenital) 511 0.392 0.808 0.010 None 1.000 1 0 2000 2000
Entrez Id: 952
Gene Symbol: CD38
CD38
P28907 CD38 molecule Enzyme 473 0.407 0.885 2.3E-06 0.010 None < 0.001 1 0 1998 1998
Entrez Id: 174
Gene Symbol: AFP
AFP
P02771 alpha fetoprotein Transporter 392 0.429 0.885 1.1E-11 0.090 None 1.000 9 0 1978 2013
Entrez Id: 335
Gene Symbol: APOA1
APOA1
P02647 apolipoprotein A1 416 0.429 0.885 5.5E-04 0.010 None 1.000 1 0 2009 2009
Entrez Id: 5047
Gene Symbol: PAEP
PAEP
P09466 progestagen associated endometrial protein Enzyme 397 0.430 0.846 3.1E-08 0.010 None 1.000 1 0 2009 2009
Entrez Id: 55636
Gene Symbol: CHD7
CHD7
Q9P2D1 chromodomain helicase DNA binding protein 7 419 0.441 0.846 1.00 0.010 None 1.000 1 0 1995 1995
Entrez Id: 604
Gene Symbol: BCL6
BCL6
P41182 BCL6 transcription repressor 309 0.444 0.808 0.96 0.020 None 0.500 2 0 2010 2013
Entrez Id: 56729
Gene Symbol: RETN
RETN
Q9HD89 resistin 302 0.454 0.808 3.7E-02 0.010 None 1.000 1 0 2019 2019
Entrez Id: 5228
Gene Symbol: PGF
PGF
P49763 placental growth factor Signaling 288 0.460 0.846 0.13 0.010 None 1.000 1 0 2014 2014
Entrez Id: 290
Gene Symbol: ANPEP
ANPEP
P15144 alanyl aminopeptidase, membrane Enzyme 280 0.462 0.769 3.7E-09 0.010 None 1.000 1 0 2002 2002
Entrez Id: 1630
Gene Symbol: DCC
DCC
P43146 DCC netrin 1 receptor 279 0.471 0.808 0.99 0.010 None 1.000 1 0 1998 1998
Entrez Id: 7012
Gene Symbol: TERC
TERC
telomerase RNA component 296 0.471 0.846 0.010 None 1.000 1 0 2012 2012
Entrez Id: 3492
Gene Symbol: IGH
IGH
immunoglobulin heavy locus 238 0.473 0.654 0.030 None 1.000 3 0 2010 2012
Entrez Id: 2690
Gene Symbol: GHR
GHR
P10912 growth hormone receptor Signaling 247 0.490 0.846 8.4E-05 0.010 None 1.000 1 0 2001 2001
Entrez Id: 330
Gene Symbol: BIRC3
BIRC3
Q13489 baculoviral IAP repeat containing 3 Enzyme modulator 209 0.491 0.769 6.6E-02 0.010 None 1.000 1 0 2011 2011
Entrez Id: 5055
Gene Symbol: SERPINB2
SERPINB2
P05120 serpin family B member 2 Enzyme modulator 183 0.502 0.808 6.4E-12 0.010 None 1.000 1 0 2009 2009
Entrez Id: 1081
Gene Symbol: CGA
CGA
P01215 glycoprotein hormones, alpha polypeptide 180 0.508 0.808 0.35 0.010 None 1.000 1 0 2000 2000
Entrez Id: 3502
Gene Symbol: IGHG3
IGHG3
P01860 immunoglobulin heavy constant gamma 3 (G3m marker) 161 0.513 0.769 0.010 None 1.000 1 0 2014 2014