Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 120892
Gene Symbol: LRRK2
LRRK2
Q5S007 leucine rich repeat kinase 2 Kinase 231 0.510 0.808 2.6E-30 0.100 None 0.971 102 8 2005 2020
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
P37840 synuclein alpha Transporter 449 0.427 0.885 0.88 0.100 None 0.941 68 5 1998 2020
Entrez Id: 5071
Gene Symbol: PRKN
PRKN
O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 409 0.431 0.846 6.9E-07 0.100 None 0.867 15 3 1999 2019
Entrez Id: 7345
Gene Symbol: UCHL1
UCHL1
P09936 ubiquitin C-terminal hydrolase L1 Enzyme 260 0.482 0.885 0.99 0.090 None 0.889 9 2 2001 2017
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
Q01959 solute carrier family 6 member 3 Transporter 373 0.453 0.885 1.00 0.040 None 1.000 4 2 1997 2019
Entrez Id: 51142
Gene Symbol: CHCHD2
CHCHD2
Q9Y6H1 coiled-coil-helix-coiled-coil-helix domain containing 2 57 0.638 0.538 1.7E-07 0.030 None 1.000 3 2 2015 2017
Entrez Id: 4521
Gene Symbol: NUDT1
NUDT1
P36639 nudix hydrolase 1 Enzyme 73 0.597 0.769 7.4E-12 0.020 None 0.500 2 2 2000 2008
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.020 None 1.000 2 2 2014 2015
Entrez Id: 1981
Gene Symbol: EIF4G1
EIF4G1
Q04637 eukaryotic translation initiation factor 4 gamma 1 Nucleic acid binding 139 0.553 0.808 1.00 0.010 None < 0.001 1 2 2013 2013
Entrez Id: 831
Gene Symbol: CAST
CAST
P20810 calpastatin 141 0.541 0.846 4.1E-12 0.010 None < 0.001 1 2 2013 2013
Entrez Id: 8224
Gene Symbol: SYN3
SYN3
O14994 synapsin III Cellular structure 38 0.686 0.462 1.9E-03 0.010 None 1.000 1 2 2014 2014
Entrez Id: 2629
Gene Symbol: GBA
GBA
P04062 glucosylceramidase beta 319 0.500 0.808 1.4E-06 0.090 None 0.889 9 1 2010 2019
Entrez Id: 1121
Gene Symbol: CHM
CHM
P24386 CHM Rab escort protein Enzyme 82 0.592 0.654 1.00 0.060 None 0.833 6 1 2003 2020
Entrez Id: 55737
Gene Symbol: VPS35
VPS35
Q96QK1 VPS35 retromer complex component Transporter 66 0.656 0.500 0.97 0.040 None 0.750 4 1 2013 2016
Entrez Id: 64127
Gene Symbol: NOD2
NOD2
Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 434 0.423 0.923 2.0E-30 0.020 None 1.000 2 1 2007 2013
Entrez Id: 84894
Gene Symbol: LINGO1
LINGO1
Q96FE5 leucine rich repeat and Ig domain containing 1 Receptor 44 0.682 0.385 0.99 0.020 None 1.000 2 1 2010 2010
Entrez Id: 9627
Gene Symbol: SNCAIP
SNCAIP
Q9Y6H5 synuclein alpha interacting protein 44 0.691 0.423 3.3E-04 0.020 None 1.000 2 1 2002 2017
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
P10636 microtubule associated protein tau 469 0.446 0.923 6.0E-03 0.020 None 1.000 2 1 2009 2016
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
P04798 cytochrome P450 family 1 subfamily A member 1 Enzyme 379 0.436 0.846 1.1E-17 0.010 None 1.000 1 1 2014 2014
Entrez Id: 3122
Gene Symbol: HLA-DRA
HLA-DRA
P01903 major histocompatibility complex, class II, DR alpha Immune response 92 0.581 0.769 0.52 0.010 None 1.000 1 1 2011 2011
Entrez Id: 6720
Gene Symbol: SREBF1
SREBF1
P36956 sterol regulatory element binding transcription factor 1 159 0.518 0.808 1.5E-02 0.010 None 1.000 1 1 2018 2018
Entrez Id: 161357
Gene Symbol: MDGA2
MDGA2
Q7Z553 MAM domain containing glycosylphosphatidylinositol anchor 2 24 0.760 0.308 0.66 0.010 None 1.000 1 1 2016 2016
Entrez Id: 219402
Gene Symbol: MTIF3
MTIF3
Q9H2K0 mitochondrial translational initiation factor 3 Nucleic acid binding 9 0.890 0.115 3.9E-07 0.010 None 1.000 1 1 2007 2007
Entrez Id: 7054
Gene Symbol: TH
TH
P07101 tyrosine hydroxylase 321 0.462 0.885 1.7E-06 0.010 None 1.000 1 1 1994 1994
Entrez Id: 9037
Gene Symbol: SEMA5A
SEMA5A
Q13591 semaphorin 5A 85 0.610 0.731 1.5E-05 0.010 None 1.000 1 1 2006 2006