Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 120892
Gene Symbol: LRRK2
LRRK2
Q5S007 leucine rich repeat kinase 2 Kinase 231 0.510 0.808 2.6E-30 0.100 None 0.971 102 8 2005 2020
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
P37840 synuclein alpha Transporter 449 0.427 0.885 0.88 0.100 None 0.941 68 5 1998 2020
Entrez Id: 5071
Gene Symbol: PRKN
PRKN
O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 409 0.431 0.846 6.9E-07 0.100 None 0.867 15 3 1999 2019
Entrez Id: 2629
Gene Symbol: GBA
GBA
P04062 glucosylceramidase beta 319 0.500 0.808 1.4E-06 0.090 None 0.889 9 1 2010 2019
Entrez Id: 7345
Gene Symbol: UCHL1
UCHL1
P09936 ubiquitin C-terminal hydrolase L1 Enzyme 260 0.482 0.885 0.99 0.090 None 0.889 9 2 2001 2017
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
Q9BXM7 PTEN induced kinase 1 Kinase 209 0.516 0.769 1.9E-10 0.070 None 1.000 7 0 2006 2018
Entrez Id: 1312
Gene Symbol: COMT
COMT
P21964 catechol-O-methyltransferase Enzyme 622 0.400 0.923 1.1E-06 0.060 None 0.833 6 0 2002 2014
Entrez Id: 1121
Gene Symbol: CHM
CHM
P24386 CHM Rab escort protein Enzyme 82 0.592 0.654 1.00 0.060 None 0.833 6 1 2003 2020
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 1049 0.338 0.962 1.9E-03 0.050 None 0.800 5 0 1997 2015
Entrez Id: 4129
Gene Symbol: MAOB
MAOB
P27338 monoamine oxidase B 152 0.533 0.808 1.00 0.040 None 1.000 4 0 2004 2012
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
Q01959 solute carrier family 6 member 3 Transporter 373 0.453 0.885 1.00 0.040 None 1.000 4 2 1997 2019
Entrez Id: 55737
Gene Symbol: VPS35
VPS35
Q96QK1 VPS35 retromer complex component Transporter 66 0.656 0.500 0.97 0.040 None 0.750 4 1 2013 2016
Entrez Id: 51142
Gene Symbol: CHCHD2
CHCHD2
Q9Y6H1 coiled-coil-helix-coiled-coil-helix domain containing 2 57 0.638 0.538 1.7E-07 0.030 None 1.000 3 2 2015 2017
Entrez Id: 3586
Gene Symbol: IL10
IL10
P22301 interleukin 10 1679 0.281 0.923 5.9E-03 0.030 None 0.333 3 0 2007 2012
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.030 None 1.000 3 0 2001 2018
Entrez Id: 100359403
Gene Symbol: PARK16
PARK16
Parkinson disease 16 (susceptibility) 5 0.861 0.077 0.030 None 1.000 3 0 2015 2016
Entrez Id: 627
Gene Symbol: BDNF
BDNF
P23560 brain derived neurotrophic factor Signaling 992 0.345 0.923 0.66 0.030 None 1.000 3 0 2007 2020
Entrez Id: 56922
Gene Symbol: MCCC1
MCCC1
Q96RQ3 methylcrotonoyl-CoA carboxylase 1 Enzyme 42 0.700 0.308 4.0E-12 0.020 None 1.000 2 0 2013 2016
Entrez Id: 54209
Gene Symbol: TREM2
TREM2
Q9NZC2 triggering receptor expressed on myeloid cells 2 239 0.519 0.769 3.3E-09 0.020 None 1.000 2 0 2016 2020
Entrez Id: 64127
Gene Symbol: NOD2
NOD2
Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 434 0.423 0.923 2.0E-30 0.020 None 1.000 2 1 2007 2013
Entrez Id: 26058
Gene Symbol: GIGYF2
GIGYF2
Q6Y7W6 GRB10 interacting GYF protein 2 54 0.711 0.269 1.00 0.020 None 1.000 2 0 2009 2010
Entrez Id: 6620
Gene Symbol: SNCB
SNCB
Q16143 synuclein beta Transporter 60 0.619 0.577 6.8E-02 0.020 None 0.500 2 0 2010 2010
Entrez Id: 6623
Gene Symbol: SNCG
SNCG
O76070 synuclein gamma Transporter 122 0.550 0.615 8.5E-04 0.020 None 0.500 2 0 2010 2010
Entrez Id: 2717
Gene Symbol: GLA
GLA
P06280 galactosidase alpha 190 0.537 0.769 1.00 0.020 None 1.000 2 0 2011 2020
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
P14416 dopamine receptor D2 G-protein coupled receptor 437 0.436 0.846 0.75 0.020 None 1.000 2 0 1997 2019