Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
P46531 notch receptor 1 693 0.369 0.885 1.00 0.600 limited 1.000 4 1 2005 2016
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
Q13485 SMAD family member 4 Transcription factor 575 0.401 0.808 1.00 0.500 limited 1.000 1 0 2019 2019
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
P37173 transforming growth factor beta receptor 2 Kinase 502 0.413 0.846 0.13 0.600 definitive 1.000 43 20 2003 2019
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
P84022 SMAD family member 3 Transcription factor 470 0.415 0.923 0.80 0.600 definitive 1.000 15 22 1999 2019
Entrez Id: 2006
Gene Symbol: ELN
ELN
P15502 elastin 545 0.415 0.885 2.1E-14 0.500 limited 1.000 1 0 2015 2015
Entrez Id: 2200
Gene Symbol: FBN1
FBN1
P35555 fibrillin 1 Calcium-binding protein 552 0.417 0.846 1.00 0.600 definitive 1.000 158 361 1973 2019
Entrez Id: 2316
Gene Symbol: FLNA
FLNA
P21333 filamin A 571 0.419 0.846 1.00 0.500 limited 1.000 7 0 2006 2016
Entrez Id: 182
Gene Symbol: JAG1
JAG1
P78504 jagged canonical Notch ligand 1 420 0.429 0.808 1.00 0.300 limited 0 0
Entrez Id: 1277
Gene Symbol: COL1A1
COL1A1
P02452 collagen type I alpha 1 chain 487 0.430 0.808 1.00 0.400 limited 0 1
Entrez Id: 7042
Gene Symbol: TGFB2
TGFB2
P61812 transforming growth factor beta 2 Signaling 389 0.433 0.885 1.00 0.600 definitive 1.000 3 0 2012 2014
Entrez Id: 2022
Gene Symbol: ENG
ENG
P17813 endoglin 371 0.446 0.846 1.00 0.300 limited 0 0
Entrez Id: 4015
Gene Symbol: LOX
LOX
P28300 lysyl oxidase 328 0.447 0.846 0.99 0.700 strong 1.000 6 2 1990 2019
Entrez Id: 80781
Gene Symbol: COL18A1
COL18A1
P39060 collagen type XVIII alpha 1 chain 323 0.449 0.808 1.7E-10 0.300 limited 0 0
Entrez Id: 7046
Gene Symbol: TGFBR1
TGFBR1
P36897 transforming growth factor beta receptor 1 Kinase 347 0.451 0.885 0.85 0.600 definitive 1.000 22 12 2005 2019
Entrez Id: 4087
Gene Symbol: SMAD2
SMAD2
Q15796 SMAD family member 2 Transcription factor 289 0.456 0.808 1.00 0.500 moderate 1.000 6 0 1996 2015
Entrez Id: 875
Gene Symbol: CBS
CBS
P0DN79 P35520 cystathionine beta-synthase Enzyme 295 0.465 0.885 3.1E-05 0.300 limited 0 0
Entrez Id: 9968
Gene Symbol: MED12
MED12
Q93074 mediator complex subunit 12 Transcription factor 340 0.476 0.769 1.00 0.300 limited 0 0
Entrez Id: 1281
Gene Symbol: COL3A1
COL3A1
P02461 collagen type III alpha 1 chain 301 0.477 0.808 1.00 0.600 definitive 1.000 10 4 1988 2015
Entrez Id: 633
Gene Symbol: BGN
BGN
P21810 biglycan 253 0.484 0.808 0.45 0.500 limited 1.000 2 0 2007 2017
Entrez Id: 1282
Gene Symbol: COL4A1
COL4A1
P02462 collagen type IV alpha 1 chain 277 0.484 0.731 1.00 0.300 limited 0 0
Entrez Id: 1278
Gene Symbol: COL1A2
COL1A2
P08123 collagen type I alpha 2 chain 271 0.486 0.846 1.00 0.300 limited 0 0
Entrez Id: 5310
Gene Symbol: PKD1
PKD1
P98161 polycystin 1, transient receptor potential channel interacting 217 0.493 0.769 1.00 0.300 limited 0 0
Entrez Id: 94
Gene Symbol: ACVRL1
ACVRL1
P37023 activin A receptor like type 1 Kinase 224 0.493 0.769 9.7E-04 0.300 limited 0 0
Entrez Id: 1301
Gene Symbol: COL11A1
COL11A1
P12107 collagen type XI alpha 1 chain 268 0.495 0.846 1.00 0.300 limited 0 0
Entrez Id: 1462
Gene Symbol: VCAN
VCAN
P13611 versican Extracellular structure 205 0.497 0.808 1.00 0.300 limited 0 0