Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		P38398 BRCA1 DNA repair associated Enzyme 747 0.367 0.923 9.2E-29 0.200 None 0.966 1199 24 1992 2020
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.500 None 0.967 276 8 1991 2020
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1 		P08183 ATP binding cassette subfamily B member 1 Transporter 933 0.344 0.885 1.3E-05 0.100 None 1.000 48 6 1989 2019
Entrez Id: 7421
Gene Symbol: VDR
VDR 		P11473 vitamin D receptor Nuclear receptor 852 0.352 0.885 1.7E-05 0.100 None 0.895 19 6 2007 2019
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		O96017 checkpoint kinase 2 Kinase 297 0.460 0.808 1.2E-24 0.200 None 0.750 12 6 2003 2019
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		P51587 BRCA2 DNA repair associated Nucleic acid binding 656 0.379 0.846 2.4E-25 0.200 None 0.944 605 5 1994 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.100 None 0.988 85 5 1999 2020
Entrez Id: 324
Gene Symbol: APC
APC 		P25054 APC regulator of WNT signaling pathway 703 0.373 0.962 1.00 0.080 None 1.000 8 5 1994 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.100 None 0.984 64 4 1995 2019
Entrez Id: 5241
Gene Symbol: PGR
PGR 		P06401 progesterone receptor Nuclear receptor 392 0.426 0.885 5.1E-02 0.100 None 0.931 29 4 1995 2019
Entrez Id: 2100
Gene Symbol: ESR2
ESR2 		Q92731 estrogen receptor 2 Nuclear receptor 528 0.400 0.923 4.5E-08 0.100 None 1.000 22 4 2004 2019
Entrez Id: 100124700
Gene Symbol: HOTAIR
HOTAIR 		HOX transcript antisense RNA 234 0.475 0.769 0.100 None 1.000 15 4 2014 2019
Entrez Id: 841
Gene Symbol: CASP8
CASP8 		Q14790 caspase 8 Enzyme 480 0.404 0.923 3.7E-06 0.070 None 1.000 7 4 2008 2019
Entrez Id: 8607
Gene Symbol: RUVBL1
RUVBL1 		Q9Y265 RuvB like AAA ATPase 1 44 0.647 0.500 1.00 0.020 None 1.000 2 4 2011 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		P15692 vascular endothelial growth factor A Signaling 1899 0.266 0.923 2.4E-05 0.100 None 0.973 113 3 1994 2019
Entrez Id: 4292
Gene Symbol: MLH1
MLH1 		P40692 mutL homolog 1 Nucleic acid binding 526 0.399 0.808 3.4E-05 0.100 None 0.920 25 3 1994 2019
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.100 None 0.833 12 3 2007 2017
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1 		P19838 nuclear factor kappa B subunit 1 Transcription factor 551 0.396 0.923 1.00 0.100 None 1.000 10 3 2006 2018
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2 		P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 499 0.420 0.846 7.1E-20 0.080 None 0.750 8 3 1997 2017
Entrez Id: 6928
Gene Symbol: HNF1B
HNF1B 		P35680 HNF1 homeobox B Nucleic acid binding 279 0.473 0.808 1.00 0.080 None 1.000 8 3 2003 2020
Entrez Id: 4968
Gene Symbol: OGG1
OGG1 		O15527 8-oxoguanine DNA glycosylase 313 0.453 0.808 3.9E-12 0.040 None 1.000 4 3 2005 2016
Entrez Id: 100750225
Gene Symbol: PCAT1
PCAT1 		prostate cancer associated transcript 1 90 0.575 0.615 0.040 None 1.000 4 3 2019 2020
Entrez Id: 93659
Gene Symbol: CGB5
CGB5 		P0DN86 chorionic gonadotropin subunit beta 5 83 0.579 0.654 2.5E-02 0.020 None 1.000 2 3 1997 2017
Entrez Id: 115761
Gene Symbol: ARL11
ARL11 		Q969Q4 ADP ribosylation factor like GTPase 11 35 0.670 0.423 5.3E-03 0.020 None 1.000 2 3 2006 2009
Entrez Id: 727677
Gene Symbol: CASC8
CASC8 		cancer susceptibility 8 35 0.670 0.462 0.010 None 1.000 1 3 2016 2016