Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 6608
Gene Symbol: SMO
SMO 		Q99835 smoothened, frizzled class receptor G-protein coupled receptor 215 0.489 0.731 4.3E-07 0.700 None 0.955 22 6 1998 2019
Entrez Id: 5921
Gene Symbol: RASA1
RASA1 		P20936 RAS p21 protein activator 1 Enzyme modulator 237 0.481 0.885 1.00 0.610 None 1.000 1 3 2001 2001
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1 		Q13635 patched 1 604 0.398 0.885 1.00 0.500 None 0.942 103 6 1994 2020
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.500 None 0.938 80 5 1992 2019
Entrez Id: 4157
Gene Symbol: MC1R
MC1R 		Q01726 melanocortin 1 receptor G-protein coupled receptor 183 0.524 0.808 8.1E-11 0.500 None 1.000 21 4 1999 2015
Entrez Id: 8314
Gene Symbol: BAP1
BAP1 		Q92560 BRCA1 associated protein 1 Enzyme 299 0.454 0.731 0.99 0.460 None 1.000 7 1 2015 2019
Entrez Id: 8643
Gene Symbol: PTCH2
PTCH2 		Q9Y6C5 patched 2 114 0.563 0.692 3.4E-16 0.460 None 1.000 6 0 1999 2018
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.450 None 1.000 6 0 2009 2019
Entrez Id: 51684
Gene Symbol: SUFU
SUFU 		Q9UMX1 SUFU negative regulator of hedgehog signaling 272 0.493 0.769 1.00 0.440 None 0.750 4 0 2005 2018
Entrez Id: 81037
Gene Symbol: CLPTM1L
CLPTM1L 		Q96KA5 CLPTM1 like Enzyme 110 0.551 0.654 4.4E-05 0.430 None 1.000 5 2 2009 2015
Entrez Id: 7507
Gene Symbol: XPA
XPA 		P23025 XPA, DNA damage recognition and repair factor Nucleic acid binding 209 0.520 0.846 7.9E-05 0.420 None 1.000 3 2 2007 2018
Entrez Id: 7299
Gene Symbol: TYR
TYR 		P14679 tyrosinase Enzyme 281 0.473 0.808 5.0E-32 0.420 None 1.000 2 1 2008 2011
Entrez Id: 51151
Gene Symbol: SLC45A2
SLC45A2 		Q9UMX9 solute carrier family 45 member 2 Transporter 75 0.626 0.538 1.7E-06 0.420 None 1.000 2 1 2009 2014
Entrez Id: 2736
Gene Symbol: GLI2
GLI2 		P10070 GLI family zinc finger 2 351 0.446 0.846 0.97 0.400 None 1.000 17 0 2000 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6 		P05231 interleukin 6 2367 0.248 0.962 0.32 0.390 None 0.900 10 1 2001 2019
Entrez Id: 3852
Gene Symbol: KRT5
KRT5 		P13647 keratin 5 203 0.512 0.731 0.64 0.350 None 1.000 6 1 2002 2019
Entrez Id: 7517
Gene Symbol: XRCC3
XRCC3 		O43542 X-ray repair cross complementing 3 184 0.505 0.769 1.9E-10 0.350 None 0.800 5 1 2004 2014
Entrez Id: 4613
Gene Symbol: MYCN
MYCN 		P04198 MYCN proto-oncogene, bHLH transcription factor Transcription factor 314 0.454 0.808 0.89 0.340 None 1.000 4 0 2006 2019
Entrez Id: 7015
Gene Symbol: TERT
TERT 		O14746 telomerase reverse transcriptase Enzyme 703 0.374 0.846 0.99 0.320 None 1.000 3 0 2009 2015
Entrez Id: 9113
Gene Symbol: LATS1
LATS1 		O95835 large tumor suppressor kinase 1 Kinase 99 0.563 0.731 1.00 0.320 None 1.000 2 0 2015 2016
Entrez Id: 434
Gene Symbol: ASIP
ASIP 		P42127 agouti signaling protein Signaling 89 0.584 0.692 1.6E-02 0.320 None 1.000 2 0 2008 2009
Entrez Id: 139741
Gene Symbol: ACTRT1
ACTRT1 		Q8TDG2 actin related protein T1 Cellular structure 26 0.711 0.308 3.7E-03 0.310 None 1.000 2 0 2017 2019
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.310 None 1.000 2 0 2016 2019
Entrez Id: 5784
Gene Symbol: PTPN14
PTPN14 		Q15678 protein tyrosine phosphatase non-receptor type 14 48 0.638 0.615 0.22 0.310 None 1.000 1 0 2016 2016
Entrez Id: 5537
Gene Symbol: PPP6C
PPP6C 		O00743 protein phosphatase 6 catalytic subunit 20 0.729 0.231 0.86 0.300 None 1.000 1 0 2016 2016