Gene: DLL4 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 54567
Gene Symbol: DLL4
DLL4 		0.100 GeneticVariation group CLINVAR Notch signaling in the brain: in good and bad times. 23570941 2013
Entrez Id: 54567
Gene Symbol: DLL4
DLL4 		0.100 GeneticVariation group CLINVAR Characterising and predicting haploinsufficiency in the human genome. 20976243 2010
Entrez Id: 54567
Gene Symbol: DLL4
DLL4 		0.100 GeneticVariation group CLINVAR Combination of Dll4/Notch and Ephrin-B2/EphB4 targeted therapy is highly effective in disrupting tumor angiogenesis. 21092311 2010
Entrez Id: 54567
Gene Symbol: DLL4
DLL4 		0.100 GeneticVariation group CLINVAR Chronic DLL4 blockade induces vascular neoplasms. 20147986 2010
Entrez Id: 54567
Gene Symbol: DLL4
DLL4 		0.100 GeneticVariation group CLINVAR Notch signaling controls liver development by regulating biliary differentiation. 19369401 2009
Entrez Id: 54567
Gene Symbol: DLL4
DLL4 		0.100 GeneticVariation group CLINVAR Inhibition of Dll4-mediated signaling induces proliferation of immature vessels and results in poor tissue perfusion. 17311993 2007
Entrez Id: 54567
Gene Symbol: DLL4
DLL4 		0.100 GeneticVariation group CLINVAR The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel branching. 17296941 2007
Entrez Id: 54567
Gene Symbol: DLL4
DLL4 		0.100 GeneticVariation group CLINVAR Notch signaling is essential for ventricular chamber development. 17336907 2007
Entrez Id: 54567
Gene Symbol: DLL4
DLL4 		0.100 GeneticVariation group CLINVAR A regulatory network involving Foxn4, Mash1 and delta-like 4/Notch1 generates V2a and V2b spinal interneurons from a common progenitor pool. 17728344 2007
Entrez Id: 54567
Gene Symbol: DLL4
DLL4 		0.100 GeneticVariation group CLINVAR NOTCH2 mutations cause Alagille syndrome, a heterogeneous disorder of the notch signaling pathway. 16773578 2006
Entrez Id: 54567
Gene Symbol: DLL4
DLL4 		0.100 GeneticVariation group CLINVAR Notch signaling, brain development, and human disease. 15817497 2005
Entrez Id: 54567
Gene Symbol: DLL4
DLL4 		0.100 GeneticVariation group CLINVAR Expression of Dll4 during mouse embryogenesis suggests multiple developmental roles. 15923152 2005
Entrez Id: 54567
Gene Symbol: DLL4
DLL4 		0.100 GeneticVariation group CLINVAR Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants. 15466160 2004
Entrez Id: 54567
Gene Symbol: DLL4
DLL4 		0.100 GeneticVariation group CLINVAR Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development. 15520367 2004
Entrez Id: 54567
Gene Symbol: DLL4
DLL4 		0.100 GeneticVariation group CLINVAR Dosage-sensitive requirement for mouse Dll4 in artery development. 15466159 2004
Entrez Id: 54567
Gene Symbol: DLL4
DLL4 		0.100 GeneticVariation group CLINVAR Regulation of Notch1 and Dll4 by vascular endothelial growth factor in arterial endothelial cells: implications for modulating arteriogenesis and angiogenesis. 12482957 2003
Entrez Id: 54567
Gene Symbol: DLL4
DLL4 		0.100 GeneticVariation group CLINVAR Angiogenesis-independent endothelial protection of liver: role of VEGFR-1. 12574630 2003
Entrez Id: 54567
Gene Symbol: DLL4
DLL4 		0.100 GeneticVariation group CLINVAR Notch signaling is required for arterial-venous differentiation during embryonic vascular development. 11585794 2001
Entrez Id: 54567
Gene Symbol: DLL4
DLL4 		0.100 GeneticVariation group CLINVAR Dll4, a novel Notch ligand expressed in arterial endothelium. 10837024 2000
Entrez Id: 54567
Gene Symbol: DLL4
DLL4 		0.100 GeneticVariation group CLINVAR Notch signaling: cell fate control and signal integration in development. 10221902 1999
Entrez Id: 54567
Gene Symbol: DLL4
DLL4 		0.100 GeneticVariation group CLINVAR Neurogenic genes and vertebrate neurogenesis. 8794055 1996
Entrez Id: 54567
Gene Symbol: DLL4
DLL4 		0.100 GeneticVariation group CLINVAR The intracellular deletions of Delta and Serrate define dominant negative forms of the Drosophila Notch ligands. 8756291 1996