Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3 		0.310 GeneticVariation disease BEFREE A dual luciferase reporter assay was performed to determine whether the SNP rs10754558 might be responsible for the altered NLRP3 gene expression in AV by disrupting the interaction between micro-RNA (miR)-4273 and NLRP3 mRNA. 29888470 2019
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3 		0.310 Biomarker disease CTD_human Pyoderma gangrenosum and its syndromic forms: evidence for a link with autoinflammation. 27106250 2016
Entrez Id: 4210
Gene Symbol: MEFV
MEFV 		0.300 Biomarker disease CTD_human Pyoderma gangrenosum and its syndromic forms: evidence for a link with autoinflammation. 27106250 2016
Entrez Id: 64127
Gene Symbol: NOD2
NOD2 		0.300 Biomarker disease CTD_human Pyoderma gangrenosum and its syndromic forms: evidence for a link with autoinflammation. 27106250 2016
Entrez Id: 9051
Gene Symbol: PSTPIP1
PSTPIP1 		0.300 Biomarker disease CTD_human Pyoderma gangrenosum and its syndromic forms: evidence for a link with autoinflammation. 27106250 2016
Entrez Id: 54984
Gene Symbol: PINX1
PINX1 		0.100 GeneticVariation disease GWASCAT Genome-wide meta-analysis implicates mediators of hair follicle development and morphogenesis in risk for severe acne. 30542056 2018
Entrez Id: 79783
Gene Symbol: SUGCT
SUGCT 		0.100 GeneticVariation disease GWASCAT Genome-wide meta-analysis implicates mediators of hair follicle development and morphogenesis in risk for severe acne. 30542056 2018
Entrez Id: 80326
Gene Symbol: WNT10A
WNT10A 		0.100 GeneticVariation disease GWASCAT Genome-wide meta-analysis implicates mediators of hair follicle development and morphogenesis in risk for severe acne. 30542056 2018
Entrez Id: 643723
Gene Symbol: LYPLAL1-DT
LYPLAL1-DT 		0.100 GeneticVariation disease GWASCAT Genome-wide meta-analysis implicates mediators of hair follicle development and morphogenesis in risk for severe acne. 30542056 2018
Entrez Id: 646023
Gene Symbol: ADORA2A-AS1
ADORA2A-AS1 		0.100 GeneticVariation disease GWASCAT Genome-wide meta-analysis implicates mediators of hair follicle development and morphogenesis in risk for severe acne. 30542056 2018
Entrez Id: 1936
Gene Symbol: EEF1D
EEF1D 		0.100 GeneticVariation disease GWASCAT Japanese GWAS identifies variants for bust-size, dysmenorrhea, and menstrual fever that are eQTLs for relevant protein-coding or long non-coding RNAs. 29855537 2018
Entrez Id: 10509
Gene Symbol: SEMA4B
SEMA4B 		0.100 GeneticVariation disease GWASCAT Genome-wide meta-analysis implicates mediators of hair follicle development and morphogenesis in risk for severe acne. 30542056 2018
Entrez Id: 399909
Gene Symbol: PCNX3
PCNX3 		0.100 GeneticVariation disease GWASCAT Genome-wide meta-analysis implicates mediators of hair follicle development and morphogenesis in risk for severe acne. 30542056 2018
Entrez Id: 79096
Gene Symbol: C11orf49
C11orf49 		0.100 GeneticVariation disease GWASCAT Two new susceptibility loci 1q24.2 and 11p11.2 confer risk to severe acne. 24399259 2014
Entrez Id: 646023
Gene Symbol: ADORA2A-AS1
ADORA2A-AS1 		0.100 GeneticVariation disease GWASCAT Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris. 24927181 2014
Entrez Id: 55732
Gene Symbol: C1orf112
C1orf112 		0.100 GeneticVariation disease GWASCAT Two new susceptibility loci 1q24.2 and 11p11.2 confer risk to severe acne. 24399259 2014
Entrez Id: 7324
Gene Symbol: UBE2E1
UBE2E1 		0.100 GeneticVariation disease GWASCAT Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris. 24927181 2014
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.060 GeneticVariation disease BEFREE This case-control study investigated the association of the TNF -308 G>A and -238 G>A SNPs with acne vulgaris in a high-risk Pakistani population. 26373312 2016
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.060 GeneticVariation disease BEFREE Carriage of the GAG haplotype of TNF is linked with borderline susceptibility to acne vulgaris. 24334867 2014
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.060 GeneticVariation disease BEFREE This meta-analysis suggests that the -308 G/A polymorphism in the TNF gene contributes to acne vulgaris risk, especially in Caucasian populations. 24498378 2014
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.060 GeneticVariation disease BEFREE Tumor necrosis factor-α -308 G/A and interleukin 10 -1082 A/G gene polymorphisms in patients with acne vulgaris. 22835835 2012
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.060 GeneticVariation disease BEFREE Genetic variants of the TNFα gene may affect the risk of acne vulgaris. 20386917 2011
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.060 GeneticVariation disease BEFREE Association study of tumor necrosis factor receptor type 2 M196R and toll-like receptor 2 Arg753Gln polymorphisms with acne vulgaris in a Chinese Han ethnic group. 20861605 2010
Entrez Id: 3552
Gene Symbol: IL1A
IL1A 		0.050 GeneticVariation disease BEFREE This study aimed to investigate the association between IL-1A (-889) gene polymorphism and acne vulgaris in a sample of patients. 29498183 2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		0.050 Biomarker disease BEFREE Is IL-1β Further Evidence for the Role of <i>Propionibacterium acnes</i> in Degenerative Disc Disease? Lessons From the Study of the Inflammatory Skin Condition Acne Vulgaris. 30155445 2018