Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
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0.070 | Biomarker | disease | BEFREE | In this report, however, the authors describe a rare case of a 61-year-old woman with hyperprolactinemia, hypothyroidism, and acromegaly (elevation of insulin-like growth factor-1 [IGF-1]) with elevated growth hormone-releasing hormone (GHRH) in whom an MRI demonstrated diffuse enlargement of the pituitary gland. | 27518527 | 2017 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | The objective of this study was to describe a multiple endocrine neoplasia type 1 (MEN1) family characterized by primary hyperparathyroidism, in association with acromegaly because of ectopic growth hormone-releasing hormone (GHRH) secretion by a pancreatic neuroendocrine tumor in a young man and with a bronchial carcinoid in his mother. | 23542451 | 2013 | ||||
|
0.070 | Biomarker | disease | BEFREE | The objective of the study is to examine whether GH secretion in acromegaly is dependent on endogenous GHRH. | 16537684 | 2006 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | The case of a 33-year-old-woman with Multiple Endocrine Neoplasia Type 1 (MEN1) syndrome and acromegaly due to ectopic growth hormone-releasing hormone (GHRH) secretion by a thymic carcinoid tumour is reported. | 12100081 | 2002 | ||||
|
0.070 | Biomarker | disease | BEFREE | GHRH observed in acromegalic and normal subjects, it is unlikely that subjects possessing the rarer form containing Thr in place of Ala at residue 57 are at increased risk of developing acromegaly. | 12220735 | 2002 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | Overexpression of the growth-hormone-releasing hormone gene in acromegaly-associated pituitary tumors. An event associated with neoplastic progression and aggressive behavior. | 9284826 | 1997 | ||||
|
0.070 | AlteredExpression | disease | BEFREE | Effects of antagonists of growth hormone-releasing hormone (GHRH) on GH and insulin-like growth factor I levels in transgenic mice overexpressing the human GHRH gene, an animal model of acromegaly. | 9348175 | 1997 |