| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.400 | GeneticVariation | group | BEFREE | Prospective study of cyclin D1 overexpression in Barrett's esophagus: association with increased risk of adenocarcinoma. | 10944553 | 2000 | ||||
|
0.400 | AlteredExpression | group | BEFREE | Moderately to poorly differentiated adenocarcinomas showed a higher incidence of nuclear cyclin D1 overexpression than papillary to well differentiated carcinomas. | 10680670 | 2000 | ||||
|
0.400 | Biomarker | group | BEFREE | Paired tumour and normal DNA samples from 26 oesophageal adenocarcinomas and 19 squamous cell carcinomas were analysed by Southern blotting with specific DNA probes for cyclin D1 and MDM-2, and for a control gene (alpha-lactalbumin). | 10419705 | 1999 | ||||
|
0.400 | Biomarker | group | BEFREE | The SIs of Ki-67 and cyclin D1 in poorly differentiated adenocarcinomas were significantly higher than in the other tumor types. | 10371338 | 1999 | ||||
|
0.400 | Biomarker | group | BEFREE | In addition, cyclin D1 amplification is associated with esophageal carcinoma of squamous cell type, being totally absent in adenocarcinomas (p < 0.01). | 9759649 | 1998 | ||||
|
0.400 | AlteredExpression | group | BEFREE | Absence of cyclin D1 expression may be a useful prognosticator for shortened survival in primary, resected NSCLCs with particular significance for adenocarcinomas. | 9815783 | 1997 | ||||
|
0.400 | AlteredExpression | group | BEFREE | These studies suggest that increased expression of cyclin D1 is an early event in the tumorigenic process of esophageal adenocarcinomas and that the increased expression of this gene might predispose the epithelium to malignant transformation. | 8781742 | 1996 | ||||
|
0.400 | AlteredExpression | group | BEFREE | We report here that overexpression of cyclin D1 resulted in abnormal mammary cell proliferation including the development of mammary adenocarcinomas. | 8208295 | 1994 | ||||
|
0.400 | GeneticVariation | group | BEFREE | We have recently reported the frequency amplification of the bcl-1 locus in squamous cell carcinomas of head and neck origin, and increased copy number also has been found in some breast adenocarcinomas. | 2170896 | 1990 |