Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4583
Gene Symbol: MUC2
MUC2
0.400 Biomarker group BEFREE Regarding the phenotypic classification based on the immunohistochemical expressions of CD10, MUC2 and MUC5AC, the incidence of unclassified type (CD10-, MUC2- and MUC5AC-) was significantly more frequent in the de novo (32%) than CIA (5%) type. 31282116 2019
Entrez Id: 4583
Gene Symbol: MUC2
MUC2
0.400 Biomarker group BEFREE High expression of MUC 1 was related to a significantly shorter overall survival, both in the whole series (p = 0.04), while adenocarcinomas positive for MUC 2 tended to have a worse overall survival (p = 0.07). 31076280 2019
Entrez Id: 4583
Gene Symbol: MUC2
MUC2
0.400 Biomarker group BEFREE The 0-IIa lesion was composed of a tubular structure positive for MUC2, and it was diagnosed as an intestinal phenotype of well differentiated adenocarcinoma. 28591047 2017
Entrez Id: 4583
Gene Symbol: MUC2
MUC2
0.400 Biomarker group BEFREE In the "specimens without polyps or adenocarcinoma" category, high (+) MUC2 positivity was more frequent in HIS than in control. 28188751 2017
Entrez Id: 4583
Gene Symbol: MUC2
MUC2
0.400 AlteredExpression group BEFREE Here, we sought to characterize the expression profile of SOX2 and CDX2 in the sequential alterations of the esophageal mucosa towards adenocarcinoma and compare it with the well-established gastric and intestinal mucin profiles (MUC5AC, MUC6, and MUC2). 27766003 2016
Entrez Id: 4583
Gene Symbol: MUC2
MUC2
0.400 Biomarker group BEFREE Mucinous balls surrounded by mesothelial cells and MUC2-positive adenocarcinoma cells are useful clues in the diagnosis of PMP.Diagn.Cytopathol.2016;44:628-631. 27079739 2016
Entrez Id: 4583
Gene Symbol: MUC2
MUC2
0.400 GeneticVariation group BEFREE The current study further showed that at the early stage (<3 months) the Muc2 knockout mice spontaneously developed chronic inflammation in colon and rectum, similar pathological features as human colitis; and at the late stage (>3 months) the mice exhibited colorectal cancer, including a unique phenotype of rectal prolapsed (rectal severe inflammation and adenocarcinoma). 24941171 2014
Entrez Id: 4583
Gene Symbol: MUC2
MUC2
0.400 AlteredExpression group BEFREE Cdx2, mucin (MUC) series (MUC2, MUC5AC and MUC6), p53 and E-cadherin expression in Barrett's esophagus and adenocarcinoma specimens were examined by immunostaining. 23382633 2013
Entrez Id: 4583
Gene Symbol: MUC2
MUC2
0.400 AlteredExpression group BEFREE On the other hand, in cases with adenocarcinoma, the expression of MUC2 was seen in 92% of cases, while TF antigen was observed in 84% and 60% of cases as detected by GOS and immunohistochemically respectively. 21381504 2011
Entrez Id: 4583
Gene Symbol: MUC2
MUC2
0.400 AlteredExpression group LHGDN Does HepPar-1 immunoexpression have a role in differential diagnosis of periampullary cancer? 18038313 2008
Entrez Id: 4583
Gene Symbol: MUC2
MUC2
0.400 AlteredExpression group BEFREE Compared with microsatellite-stable mucinous carcinoma, microsatellite-unstable mucinous carcinomas were significantly associated with a proximal location, intra- and peritumoral inflammatory cell infiltration, frequent MUC5AC expression, a low incidence of lymph node metastasis and absent hMLH1 protein expression, which is not different to medullary type poorly differentiated adenocarcinoma except for MUC2 expression and age-related occurrence. 17316416 2007
Entrez Id: 4583
Gene Symbol: MUC2
MUC2
0.400 AlteredExpression group BEFREE Sox2 was found to be transcribed in G and GI-mixed type adenocarcinomas in accordance with MUC5AC and MUC6 expression, while Cdx1 and Cdx2 were up-regulated in GI-mixed and I types along with the expression of MUC2 and villin. 15910596 2005
Entrez Id: 4583
Gene Symbol: MUC2
MUC2
0.400 AlteredExpression group BEFREE Pancreatic mucinous noncystic (colloid) carcinomas (MNCC) differ from the usual ductal adenocarcinomas in their mucin expression profile and share with many extrapancreatic mucinous carcinomas the expression of MUC2. 12808058 2003
Entrez Id: 4583
Gene Symbol: MUC2
MUC2
0.400 Biomarker group BEFREE In the present work we evaluated, by immunohistochemistry, the presence and the expression of PCNA, p53, HSP60, HSP10 and MUC-2 in a series of nodular hyperplasia, low- and high-grade prostatic intraepithelial lesions and adenocarcinomas. 12820390 2003
Entrez Id: 4583
Gene Symbol: MUC2
MUC2
0.400 Biomarker group CTD_human Short chain fatty acids and colon cancer. 12468628 2002
Entrez Id: 4583
Gene Symbol: MUC2
MUC2
0.400 Biomarker group BEFREE The latter shows a pattern similar to the conventional ductal adenocarcinomas with a loss of MUC2 and a gain of MUC1 and has a greater tendency to metastasize. 12210083 2002
Entrez Id: 4583
Gene Symbol: MUC2
MUC2
0.400 AlteredExpression group BEFREE In high grade dysplasia and adenocarcinoma there was downregulation of MUC2, MUC3, MUC5AC, and MUC6, but upregulation of MUC1 and MUC4 in half of the specimens examined. 11076872 2000
Entrez Id: 4583
Gene Symbol: MUC2
MUC2
0.400 Biomarker group BEFREE Racial differences in the prognostic usefulness of MUC1 and MUC2 in colorectal adenocarcinomas. 11051251 2000
Entrez Id: 4583
Gene Symbol: MUC2
MUC2
0.400 AlteredExpression group BEFREE All but 1 of the 10 metastatic colon adenocarcinomas expressed MUC2, whereas none expressed MUC5AC. 10872659 2000
Entrez Id: 4583
Gene Symbol: MUC2
MUC2
0.400 AlteredExpression group BEFREE By contrast, MUC2 was focally expressed in non-dysplastic as well as in dysplastic epithelia and more frequently in well-differentiated adenocarcinoma. 10398137 1999
Entrez Id: 4583
Gene Symbol: MUC2
MUC2
0.400 Biomarker group BEFREE A total of 40 breast carcinomas (22 of mucinous and 18 of ductal invasive type), 39 ovarian adenocarcinomas (16 mucinous, 23 serous), 47 colorectal carcinomas (25 mucinous and 22 non-mucinous), and 41 pancreatic adenocarcinomas (14 mucinous, 27 non-mucinous) were investigated by immunohistochemistry with the anti-MUC2 monoclonal antibody 4F1 and the expression pattern was ranked. 9306958 1997
Entrez Id: 4583
Gene Symbol: MUC2
MUC2
0.400 AlteredExpression group BEFREE Western blot analysis of the cell homogenate showed higher expression of MUC2 apomucin and mucin-associated carbohydrate antigens, such as T, Tn and sialyl Tn, with decreased sialyl Le(x) expression in C1a cells compared with HM3. 9291818 1997
Entrez Id: 4583
Gene Symbol: MUC2
MUC2
0.400 AlteredExpression group BEFREE The alterations of MUC2 expression detected by immunohistochemistry in adenocarcinomas were confirmed on mRNA level. 7927933 1994