| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.070 | AlteredExpression | group | BEFREE | CEACAM6 expression increased from columnar lined epithelium (CLE) to BE with a subsequent decrease to dysplasia and adenocarcinoma. | 28475729 | 2017 | ||||
|
0.070 | AlteredExpression | group | BEFREE | Using the Caco-2 human adenocarcinoma cell line, this study showed that the incubation of human cells with a polymeric formula (PF) resulted in a dose-dependent increase in the expression of CEACAM6, and that this effect was most noticeable on the cell surface. | 24326999 | 2014 | ||||
|
0.070 | AlteredExpression | group | BEFREE | Adenocarcinomas with elevated CEACAM6 expression were significantly associated with lymph node metastases and advanced stages. | 25299082 | 2014 | ||||
|
0.070 | Biomarker | group | BEFREE | In breast tumors, CEACAM6 was highest in papillary > infiltrating ductal > lobular > phyllodes; in pancreatic tumors, moderately-differentiated > well-differentiated > poorly-differentiated tumors; mucinous ovarian adenocarcinomas had almost 3-fold more CEACAM6 than serous ovarian adenocarcinomas; lung adenocarcinomas > squamous tumors; and liver metastases of colonic carcinoma > primary tumors = lymph nodes metastases > normal intestine. | 17201906 | 2007 | ||||
|
0.070 | Biomarker | group | LHGDN | CEACAM6 is an important determinant of pancreatic adenocarcinoma malignant cellular behavior and, together with its downstream targets, warrants further investigation as a therapeutic target in this disease. | 15208677 | 2004 | ||||
|
0.070 | AlteredExpression | group | LHGDN | CEACAM6 is a determinant of pancreatic adenocarcinoma cellular invasiveness. | 15316565 | 2004 | ||||
|
0.070 | Biomarker | group | BEFREE | CEACAM6 is an important determinant of pancreatic adenocarcinoma malignant cellular behavior and, together with its downstream targets, warrants further investigation as a therapeutic target in this disease. | 15208677 | 2004 | ||||
|
0.070 | Biomarker | group | BEFREE | NCA (nonspecific cross-reacting antigen), a glycoprotein found in normal lung and spleen, is immunologically related to carcinoembryonic antigen (CEA), which is found in over 95% of colon adenocarcinomas. | 2830274 | 1988 |